Results 61 to 70 of about 10,305 (194)

Neonatal foal death due to infection with equine arteritis virus in Belgium [PDF]

, 2009
This case report describes a small outbreak of neonatal foal death in Belgium due to infection with equine arteritis virus (EAV). The outbreak started with one foal suffering from acute dyspnea four days after birth.
Chiers, Koen, Ducatelle, Richard, Govaere, Jan, Gryspeerdt, Annick, Nauwynck, Hans, Van de Walle, Gerlinde, Vercauteren, Griet   +6 more
core  

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

The Paradox of Feline Coronavirus Pathogenesis: A Review

Advances in Virology, 2011
Feline coronavirus (FCoV) is an enveloped single-stranded RNA virus, of the family Coronaviridae and the order Nidovirales. FCoV is an important pathogen of wild and domestic cats and can cause a mild or apparently symptomless enteric infection ...
Luciana Wanderley Myrrha, Fernanda Miquelitto Figueira Silva, Ethel Fernandes de Oliveira Peternelli, Abelardo Silva Junior, Maurício Resende, Márcia Rogéria de Almeida   +5 more
doaj   +1 more source

Letalidad por SARS-COV-2 a nivel mundial

Repertorio de Medicina y Cirugía, 2021
Introducción: el nuevo coronavirus 2019 es un virus de ARN de sentido positivo no fraccionado que corresponde a la familia Coronaviridae-Nidovirales. Desde la aparición de la enfermedad por coronavirus 2019 (COVID-19) en diciembre 2019, la enfermedad se
Jorge Enrique Díaz Pinzón
doaj   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, Volume 13, Issue 11, 23 February 2026.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Vector competence of anthropophilic mosquitoes for a new mesonivirus in Senegal

Emerging Microbes and Infections, 2020
The mesoniviruses (MESOVs) belong to the newly described Mesoniviridae family (Order: Nidovirales). They have never been reported in Senegal until recently during a study in arbovirus emergence with the detection of a new species of MESOV named Dianke ...
Alioune Gaye, Moussa Moïse Diagne, El Hadji Ndiaye, Marie Henriette Dior Ndione, Martin Faye, Cheikh Talla, Gamou Fall, Yamar Ba, Diawo Diallo, Ibrahima Dia, Pascal Handschumacher, Ousmane Faye, Amadou Alpha Sall, Mawlouth Diallo   +13 more
doaj   +1 more source

Inhibition of HSP90 attenuates porcine reproductive and respiratory syndrome virus production in vitro [PDF]

, 2014
BACKGROUND: Porcine reproductive and respiratory syndrome virus (PRRSV) infection leads to substantial economic losses to the swine industry worldwide. However, no effective countermeasures exist to combat this virus infection so far.
Delin Mo, Jintao Gao, Liangliang Wang, Qianqian Ji, Shuqi Xiao, Xiaohong Liu, Xiaoyu Zhang, Yaosheng Chen, Yue Wang   +8 more
core   +1 more source

Complete Genome Sequence of Macrobrachium rosenbergii Golda Virus (MrGV) from China

Animals, 2021
In a meta-transcriptome study of the giant freshwater prawn Macrobrachium rosenbergii sampled in 2018 from a hatchery, we identified a variant of Macrobrachium rosenbergii golda virus (MrGV) in postlarvae without clinical signs.
Fanzeng Meng, Yiting Wang, Guohao Wang, Tao Hu, La Xu, Kathy F. J. Tang, Weifeng Shi, Fan Zhang, Xuan Dong, Jie Huang   +9 more
doaj   +1 more source

Coronaviruses Detected in Brazilian Wild Birds Reveal Close Evolutionary Relationships with Beta- and Deltacoronaviruses Isolated From Mammals [PDF]

, 2015
This study showed that the most of the coronaviruses (CoVs) detected in Brazilian wild birds clustered with the mouse hepatitis virus A59 strain, belonging to the BetaCoV group. Furthermore, CoV detected in two different bird species, Amazona vinacea and
Arns, Clarice W, Arns, Clarice W., Barnabé, Ana C. S., Carvalho, Ricardo Duraes de, Caserta, Leonardo C., Felippe, Paulo A. N., Ferreira, Helena L., Martini, Matheus C., Santos, Márcia B.   +8 more
core   +1 more source

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source