Results 71 to 80 of about 10,305 (194)

Identification of aNidoviralesOrf1a N7-guanine cap Methyltransferase signature-sequence as a genetic marker of large genomeTobaniviridae [PDF]

, 2019
AbstractMembers of theNidoviralesorder have (+)RNA genomes amongst the largest in size in the RNA virus world. Expression of their genes is promoted through reading of genomic RNA and mRNA transcripts by the ribosome of the infected cell. The 5’-end of these RNAs is supposedly protected by an RNA-cap structure (m7GpppNm) whose most synthesis steps ...
Ferron, François, Debat, Humberto Julio, Decroly, Etienne, Canard, Bruno   +3 more
openaire   +1 more source

Immunological Features of the Non-Structural Proteins of Porcine Reproductive and Respiratory Syndrome Virus [PDF]

, 2015
Porcine reproductive and respiratory syndrome virus (PRRSV) is currently one of the most important viruses affecting the swine industry worldwide. Despite the large number of papers published each year, the participation of non-structural proteins (nsps)
Burgara Estrella, Alexel, Hernández, Jesús, Mateu de Antonio, Enrique María, Rascón Castelo, Edgar   +3 more
core   +4 more sources

Remdesivir in COVID‐19: A Focus on Pediatric Cardiac Patients

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
The coronavirus disease 2019 (COVID‐19) pandemic has presented a significant global health challenge that necessitated the immediate search for various therapeutic modalities. Remdesivir, an antiviral drug inhibiting RNA‐dependent RNA polymerase (RdRp), was among the most heavily used drugs against COVID‐19.
Dima Bsat, Dalia Safi, Mariam Arabi, Mamunur Rahman Malik   +3 more
wiley   +1 more source

Subclinical infection of macaques and baboons with a baboon simarterivirus [PDF]

, 2018
Simarteriviruses (Arteriviridae: Simarterivirinae) are commonly found at high titers in the blood of African monkeys but do not cause overt disease in these hosts.
Bailey, Adam L, Baker, David A, Brasky, Kathy, Buechler, Connor R, Chavez, Deborah, Cornish, Joseph P, Guerra, Bernadette, Johnson, Reed F, Kuhn, Jens H, Lanford, Robert, Newman, Christina, O\u27Connor, David H, Semler, Matthew   +12 more
core   +2 more sources

Numb‐Associated Kinases‐Mediated AP2M1 Activation Facilitates Porcine Reproductive and Respiratory Syndrome Virus Entry

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine reproductive and respiratory syndrome virus (PRRSV) is a major pathogen that poses a considerable threat to the global swine industry, particularly with emerging variants that complicate control efforts. However, the host factors involved in PRRSV entry are not well understood.
Longxiang Zhang, Rui Li, Lingqiao You, Yan Jiang, Xinrong Wang, Junhai Zhu, Nan Yan, Yue Wang, Jianchao Wei   +8 more
wiley   +1 more source

Genetic and Respiratory Pathogenic Comparison of Two PRRSV‐2 Isolates Classified as Lineage Korean A and B

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine reproductive and respiratory syndrome virus (PRRSV) continues to cause substantial economic losses worldwide, and certain lineages circulate in specific countries. Lineage Korean A (LKA), B (LKB), and C (LKC) have been reported exclusively in Korea. However, studies on LKA and LKB have been limited to strains isolated before 2015. In this study,
Hyejin Na, Chanhee Chae, Nan-hua Chen
wiley   +1 more source

A case for a CUG-initiated coding sequence overlapping torovirus ORF1a and encoding a novel 30 kDa product

Virology Journal, 2009
The genus Torovirus (order Nidovirales) includes a number of species that infect livestock. These viruses have a linear positive-sense ssRNA genome of ~25-30 kb, encoding a large polyprotein that is expressed from the genomic RNA, and several additional ...
Atkins John F, Firth Andrew E
doaj   +1 more source

A Natural Recombinant NADC30‐Like PRRSV Strain in China: Intersection of CH‐1a, QYYZ, and JXA1 Lineages

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine reproductive and respiratory syndrome virus (PRRSV) remains a major threat to global swine production. In this study, a novel strain (PRRSV‐AH1) was isolated during a respiratory disease outbreak at a commercial swine operation in Anhui Province, China. Viral replication in MARC‐145 cells was confirmed by observing cytopathic effects (CPEs) and
Heng Zhang, Chengxin Zhang, Yingru Ma, Qin Zhao, Ximei Wang, Qing Pan, Yani Sun, Nan-hua Chen   +7 more
wiley   +1 more source

Candidates in Astroviruses, Seadornaviruses, Cytorhabdoviruses and Coronaviruses for +1 frame overlapping genes accessed by leaky scanning [PDF]

, 2010
Background Overlapping genes are common in RNA viruses where they serve as a mechanism to optimize the coding potential of compact genomes. However, annotation of overlapping genes can be difficult using conventional gene-finding software.
Andrew E Firth, John F Atkins, AE Firth, AE Firth, BYW Chung, AE Firth, AE Firth, E Balmori Melian, R Belshaw, B Jiang, MM Willcocks, C Touriol, SR Finkbeiner, HC Zhu, R Rivera, A Kapoor, SS Monroe, SA Sedman, M Kozak, TL Lewis, U Geigenmüller, H Attoui, H Attoui, H Attoui, F Mohd Jaafar, D Matsuda, H Attoui, T Wetzel, RG Dietzgen, F Heim, JN Barr, CP Joshi, IK Jordan, C Rancurel, AE Gorbalenya, AO Pasternak, SD Senanayake, PC Woo, BQ Dong, ML Powell, DK Chu, SF Altschul, MA Larkin, P Rice   +43 more
core   +2 more sources

A Narrative Review on the Recent Insights Into the Pathogenicity and Potential Role of Middle East Respiratory Syndrome Coronavirus (MERS‐CoV) in the Emergence of “Disease X”

Health Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aims Following the end of the COVID‐19 global emergency, concern has shifted to “Disease X,” a hypothetical, highly transmissible, and deadly pathogen, and Middle East Respiratory Syndrome Coronavirus (MERS‐CoV) is a prime candidate for this. This review explores its epidemiology, mutations, transmission, and potential to become
Zubaier Ahmed, Kazi Milenur Rahman Prattay, Sabrina Sharmin, Fatema‐Tuz‐Zohora, Asef Raj, Forhad Bin Faruk, Bagdad Ahmed, Humair Bin Md Omer, Anika Awal Omi, Fazle Rabbi, Nasiba Binte Bahar, Sumiya Sharmin Mou, Mehedi Islam, Eshaba Karim, Md. Elias Al‐Mamun   +14 more
wiley   +1 more source