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Novel Rodent Arterivirus Detected in the Brazilian Amazon [PDF]

open access: yesViruses, 2023
As part of a continuous effort to investigate the viral communities associated with wild mammals at the human–animal interface in an Amazonian metropolitan region, this study describes the detection of a novel rodent-borne arterivirus.
Thito Yan Bezerra da Paz   +2 more
exaly   +4 more sources

The neonatal Fc receptor (FcRn) is a pan-arterivirus receptor [PDF]

open access: yesNature Communications
Arteriviruses infect a variety of mammalian hosts, but the receptors used by these viruses to enter cells are poorly understood. We identified the neonatal Fc receptor (FcRn) as an important pro-viral host factor via comparative genome-wide CRISPR ...
Teressa Shaw   +2 more
exaly   +3 more sources

Novel Arterivirus Associated with Outbreak of Fatal Encephalitis in European Hedgehogs, England, 2019 [PDF]

open access: yesEmerging Infectious Diseases, 2021
In the fall of 2019, a fatal encephalitis outbreak led to the deaths of >200 European hedgehogs (Erinaceus europaeus) in England. We used next-generation sequencing to identify a novel arterivirus with a genome coding sequence of only 43% similarity to ...
Akbar Dastjerdi   +2 more
exaly   +4 more sources

Elucidating the enigmatic biology of arteriviruses through receptor discovery [PDF]

open access: yesJournal of Virology
Arteriviruses are diverse +ssRNA viruses (Nidovirales Order; Arteriviridae Family) that infect a variety of mammals. Arterivirus infections can manifest in a variety of ways, ranging from viral hemorrhagic fever to persistent sub-clinical infection.
Adam L. Bailey
doaj   +2 more sources

Wildlife nidoviruses: biology, epidemiology, and disease associations of selected nidoviruses of mammals and reptiles [PDF]

open access: yesmBio, 2023
Wildlife is the source of many emerging infectious diseases. Several viruses from the order Nidovirales have recently emerged in wildlife, sometimes with severe consequences for endangered species. The order Nidovirales is currently classified into eight
Andrew S. Flies   +7 more
doaj   +2 more sources

An intermolecular salt bridge linking substrate binding and P1 substrate specificity switch of arterivirus 3C-like proteases [PDF]

open access: yesComputational and Structural Biotechnology Journal, 2022
Equine arteritis virus (EAV) and porcine reproductive and respiratory syndrome virus (PRRSV) represent two members of the family Arteriviridae and pose a major threat to the equine- and swine-breeding industries throughout the world.
Qian Chen   +9 more
doaj   +2 more sources

Phylogenomic Characterization of Lopma Virus and Praja Virus, Two Novel Rodent-Borne Arteriviruses [PDF]

open access: yesViruses, 2021
Recent years have witnessed the discovery of several new viruses belonging to the family Arteriviridae, expanding the known diversity and host range of this group of complex RNA viruses.
Bert Vanmechelen   +7 more
doaj   +2 more sources

Conserved Antagonization of Type I Interferon Signaling by Arterivirus GP5 Proteins [PDF]

open access: yesViruses
Arteriviruses can establish persistent infections in animals such as equids, pigs, nonhuman primates, rodents, and possums. Some Arteriviruses can even cause overt and severe diseases such as Equine Arteritis in horses and Porcine Reproductive and ...
Rissar Siringo Ringo   +3 more
doaj   +2 more sources

An intra-family conserved high-order RNA structure within the M ORF is important for arterivirus subgenomic RNA accumulation and infectious virus production [PDF]

open access: yesJournal of Virology
Synthesis of subgenomic RNAs is a strategy commonly used by polycistronic positive-sense single-stranded RNA viruses to express 3′-proximal genes. Members of the order Nidovirales, including coronaviruses and arteriviruses, use a unique discontinuous ...
Pengcheng Shang   +6 more
doaj   +2 more sources

CD81 is a receptor for equine arteritis virus (family: Arteriviridae) [PDF]

open access: yesmBio
Arteriviruses are a family of single-stranded, positive-sense RNA (+ssRNA) viruses that infect diverse animal hosts. Many arteriviruses are macrophage-tropic, consistent with their utilization of the macrophage-specific molecule CD163 as a receptor ...
Sara M. Maloney   +10 more
doaj   +2 more sources

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