Equine arteritis virus (EAV) is a prototype member of the Arterivirus family, comprising important pathogens of domestic animals. Minor glycoproteins of Arteriviruses are responsible for virus entry and cellular tropism.
Anna Karolina Matczuk +2 more
doaj +1 more source
Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication [PDF]
All positive strand RNA viruses are known to replicate their genomes in close association with intracellular membranes. In case of the hepatitis C virus (HCV), a member of the family Flaviviridae, infected cells contain accumulations of vesicles forming ...
Antony, Claude +13 more
core +3 more sources
Arterivirus molecular biology and pathogenesis
Arteriviruses are positive-stranded RNA viruses that infect mammals. They can cause persistent or asymptomatic infections, but also acute disease associated with a respiratory syndrome, abortion or lethal haemorrhagic fever. During the past two decades, porcine reproductive and respiratory syndrome virus (PRRSV) and, to a lesser extent, equine ...
Snijder, E.J., Kikkert, M., Fang, Y.
openaire +3 more sources
Arteriviruses are enveloped positive-strand RNA viruses that assemble and egress using the host cell's exocytic pathway. In previous studies, we demonstrated that most arteriviruses use a unique -2 ribosomal frameshifting mechanism to produce a C ...
Rui Guo +7 more
doaj +1 more source
New insights on the role of paired membrane structures in coronavirus replication [PDF]
The replication of coronaviruses, as in other positive-strand RNA viruses, is closely tied to the formation of membrane-bound replicative organelles inside infected cells. The proteins responsible for rearranging cellular membranes to form the organelles
Al-Mulla +99 more
core +1 more source
A novel porcine reproductive and respiratory syndrome virus vector system that stably expresses enhanced green fluorescent protein as a separate transcription unit [PDF]
Here we report the rescue of a recombinant porcine reproductive and respiratory syndrome virus (PRRSV) carrying an enhanced green fluorescent protein (EGFP) reporter gene as a separate transcription unit.
Almazán, Fernando +17 more
core +3 more sources
MiR-125b reduces porcine reproductive and respiratory syndrome virus replication by negatively regulating the NF-κB pathway. [PDF]
Porcine reproductive and respiratory syndrome virus (PRRSV) is an Arterivirus that has been devastating the swine industry worldwide since the late 1980s.
Dang Wang +9 more
doaj +1 more source
Purification and electron cryomicroscopy of coronavirus particles. [PDF]
Intact, enveloped coronavirus particles vary widely in size and contour, and are thus refractory to study by traditional structural means such as X-ray crystallography. Electron microscopy (EM) overcomes some problems associated with particle variability
Adair, Brian D +3 more
core +1 more source
Toll-like Receptor 3 Activation Decreases Porcine Arterivirus Infection [PDF]
Porcine reproductive and respiratory syndrome virus (PRRSV) is an RNA virus that initiates infection in pulmonary alveolar macrophages (PAMs), elicits weak immune responses, and establishes a persistent infection. To understand the role of dsRNA intermediates in eliciting host immunity, we sought to determine if toll-like receptor-3 (TLR3), a well ...
Yongming, Sang +3 more
openaire +2 more sources
NSP2 gene variation of the North American genotype of the Thai PRRSV in central Thailand [PDF]
Porcine reproductive and respiratory syndrome virus (PRRSV) is a major swine pathogen causing economic losses in the swine industry almost worldwide.
Roongtham Kedkovid +3 more
core +2 more sources

