Results 61 to 70 of about 3,240 (195)

Equine Arteritis Virus Does Not Induce Interferon Production in Equine Endothelial Cells: Identification of Nonstructural Protein 1 as a Main Interferon Antagonist

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
The objective of this study was to investigate the effect of equine arteritis virus (EAV) on type I interferon (IFN) production. Equine endothelial cells (EECs) were infected with the virulent Bucyrus strain (VBS) of EAV and expression of IFN‐β was measured at mRNA and protein levels by quantitative real‐time RT‐PCR and IFN bioassay using vesicular ...
Yun Young Go, Yanhua Li, Zhenhai Chen, Mingyuan Han, Dongwan Yoo, Ying Fang, Udeni B. R. Balasuriya, Denis Archambault   +7 more
wiley   +1 more source

Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Nsp4 Cleaves VISA to Impair Antiviral Responses Mediated by RIG-I-like Receptors [PDF]

, 2016
Citation: Huang, C., Du, Y. P., Yu, Z. B., Zhang, Q., Liu, Y. H., Tang, J., . . . Feng, W. H. (2016). Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Nsp4 Cleaves VISA to Impair Antiviral Responses Mediated by RIG-I-like Receptors ...
Du, Y. P., Feng, W. H., Huang, C., Liu, Y. H., Shi, Jishu, Tang, J., Yu, Z. B., Zhang, Q.   +7 more
core   +2 more sources

The Effects of the Context‐Dependent Codon Usage Bias on the Structure of the nsp1α of Porcine Reproductive and Respiratory Syndrome Virus

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
The information about the crystal structure of porcine reproductive and respiratory syndrome virus (PRRSV) leader protease nsp1α is available to analyze the roles of tRNA abundance of pigs and codon usage of the nsp1α gene in the formation of this protease.
Yao-zhong Ding, Ya-nan You, Dong-jie Sun, Hao-tai Chen, Yong-lu Wang, Hui-yun Chang, Li Pan, Yu-zhen Fang, Zhong-wang Zhang, Peng Zhou, Jian-liang Lv, Xin-sheng Liu, Jun-jun Shao, Fu-rong Zhao, Tong Lin, Laszlo Stipkovits, Zygmunt Pejsak, Yong-guang Zhang, Jie Zhang, Hongwei Wang   +19 more
wiley   +1 more source

Isolation and Characterization of an Arterivirus Defective Interfering RNA Genome [PDF]

Journal of Virology, 2000
ABSTRACT Equine arteritis virus (EAV), the type member of the family Arteriviridae , is a single-stranded RNA virus with a positive-stranded genome of approximately 13 kb. EAV uses a discontinuous transcription mechanism to produce a nested set of six subgenomic mRNAs from which its structural ...
R, Molenkamp, B C, Rozier, S, Greve, W J, Spaan, E J, Snijder   +4 more
openaire   +2 more sources

Infection Load and Prevalence of Novel Viruses Identified from the Bank Vole Do Not Associate with Exposure to Environmental Radioactivity

Viruses, 2019
Bank voles (Myodes glareolus) are host to many zoonotic viruses. As bank voles inhabiting areas contaminated by radionuclides show signs of immunosuppression, resistance to apoptosis, and elevated DNA repair activity, we predicted an association between ...
Jenni Kesäniemi, Anton Lavrinienko, Eugene Tukalenko, Tapio Mappes, Phillip C. Watts, Jaana Jurvansuu   +5 more
doaj   +1 more source

Attenuation and Immunogenicity of a Live High Pathogenic PRRSV Vaccine Candidate with a 32‐Amino Acid Deletion in the nsp2 Protein

Journal of Immunology Research, Volume 2014, Issue 1, 2014., 2014
A porcine reproductive and respiratory syndrome virus (PRRSV) QY1 was serially passed on Marc‐145 cells. Virulence of different intermediate derivatives of QY1 (P5, P60, P80, and P100) were determined. The study found that QY1 had been gradually attenuated during the in vitro process.
Wenhui Lu, Baoli Sun, Jianyue Mo, Xiduo Zeng, Guanqun Zhang, Lianxiang Wang, Qingfeng Zhou, Ling Zhu, Zhili Li, Qingmei Xie, Yinzuo Bi, Jingyun Ma, Yong-Suk Jang   +12 more
wiley   +1 more source

Endogenous Antimicrobial‐Immunomodulatory Molecules: Networking Biomolecules of Innate Immunity

ChemBioChem, Volume 25, Issue 12, June 17, 2024.
A network of biomolecules (peptides, saccharides, lipids, nucleic acids, organic molecules, metal ions) endogenous to the human brain and exhibiting both antimicrobial and immunomodulatory activities has been identified. This network constitutes a previously uncatalogued and collectively underappreciated immuno‐active group of synergistic molecular ...
Donald F. Weaver
wiley   +1 more source

Prevalence and Risk Factors of Toxoplasma gondii in Fattening Pigs Farm from Yucatan, Mexico

BioMed Research International, Volume 2013, Issue 1, 2013., 2013
The objective of this study was to estimate the prevalence and identify risk factors associated with the presence of Toxoplasma gondii in pig‐fattening farms from Yucatan, Mexico. A cross‐sectional study was conducted with a two‐stage sampling. There were 429 pigs sampled from 39 farms randomly selected.
A. Ortega-Pacheco, K. Y. Acosta Viana, E. Guzmán-Marín, J. C. Segura-Correa, M. Álvarez-Fleites, M. Jiménez-Coello, María Sol Arias Vázquez   +6 more
wiley   +1 more source

Specific Detection of Two Divergent Simian Arteriviruses Using RNAscope In Situ Hybridization. [PDF]

PLoS ONE, 2016
Simian hemorrhagic fever (SHF) is an often lethal disease of Asian macaques. Simian hemorrhagic fever virus (SHFV) is one of at least three distinct simian arteriviruses that can cause SHF, but pathogenesis studies using modern methods have been scarce ...
Shu Qìng Yú, Yíngyún Caì, Cassandra Lyons, Reed F Johnson, Elena Postnikova, Steven Mazur, Joshua C Johnson, Sheli R Radoshitzky, Adam L Bailey, Michael Lauck, Tony L Goldberg, David H O'Connor, Peter B Jahrling, Thomas C Friedrich, Jens H Kuhn   +14 more
doaj   +1 more source

The role of porcine reproductive and respiratory syndrome (PRRS) virus structural and non-structural proteins in virus pathogenesis

, 2010
Porcine reproductive and respiratory syndrome (PRRS) is an economically devastating viral disease affecting the swine industry worldwide. The etiological agent, PRRS virus (PRRSV), possesses a RNA viral genome with nine open reading frames (ORFs).
Albina, Arrese, Carl A. Gagnon, Cavanagh, de Haan, de Vries, de Vries, Dea, den Boon, den Boon, Duan, Faaberg, Ferrin, Fitter, Gagnon, Hasegawa, Keffaber, Lee, Loula, Magar, Mardassi, Mardassi, McNabb, Meulenberg, Nedzad Music, Nelsen, Nelson, Pirzadeh, Plagemann, Plana Duran, Reitter, Roossinck, Seuberlich, Sincock, Snijder, Snijder, Suarez, Sur, Sur, van Dinten, van Dinten, van Marle, van Nieuwstadt, Vennema, Wassenaar, Wootton, Wootton   +46 more
core   +1 more source