Actinobacillus pleuropneumoniae Possesses an Antiviral Activity against Porcine Reproductive and Respiratory Syndrome Virus [PDF]
Pigs are often colonized by more than one bacterial and/or viral species during respiratory tract infections. This phenomenon is known as the porcine respiratory disease complex (PRDC). Actinobacillus pleuropneumoniae (App) and porcine reproductive and
Burciaga Nava, Jorge A. +6 more
core +7 more sources
Nonstructural proteins nsp2TF and nsp2N of porcine reproductive and respiratory syndrome virus (PRRSV) play important roles in suppressing host innate immune responses. [PDF]
Recently, we identified a unique -2/-1 ribosomal frameshift mechanism in PRRSV, which yields two truncated forms of nonstructural protein (nsp) 2 variants, nsp2TF and nsp2N.
Carrillo, C +9 more
core +1 more source
Cyclophilin Inhibitors Block Arterivirus Replication by Interfering with Viral RNA Synthesis [PDF]
ABSTRACT Virus replication strongly depends on cellular factors, in particular, on host proteins. Here we report that the replication of the arteriviruses equine arteritis virus (EAV) and porcine reproductive and respiratory syndrome virus (PRRSV) is strongly affected by low-micromolar concentrations of cyclosporine A (CsA), an ...
Wilde, A.H. de +7 more
openaire +3 more sources
Interferon (IFN) cytokines induce an autonomous antiviral state in cells of the infected site to restrict virus spreading and critically regulate overall antiviral response.
Damarius S. Fleming +5 more
doaj +1 more source
Characterization of the putative wobbly possum disease virus : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Virology at Massey University, Manawatū, New Zealand [PDF]
The objective of this PhD was to characterise a marsupial arterivirus, termed wobbly possum disease virus (WPDV), and to confirm aetiological involvement of the virus in the development of a neurological disease of the Australian brushtail possum ...
Giles, Julia Christine
core
Identification of a new cell line permissive to porcine reproductive and respiratory syndrome virus infection and replication which is phenotypically distinct from MARC-145 cell line [PDF]
Background Airborne transmitted pathogens, such as porcine reproductive and respiratory syndrome virus (PRRSV), need to interact with host cells of the respiratory tract in order to be able to enter and disseminate in the host organism.
Del Castillo, Jérôme +7 more
core +1 more source
Cryptoporus volvatus extract inhibits porcine reproductive and respiratory syndrome virus (PRRSV) in vitro and in vivo. [PDF]
Porcine reproductive and respiratory syndrome virus (PRRSV) is an important arterivirus that can cause significant losses in swine industry. At present, there are no adequate control strategies against PRRSV.
Li Gao +7 more
doaj +1 more source
Infection with nidoviruses like corona- and arteriviruses induces a reticulovesicular network of interconnected endoplasmic reticulum (ER)-derived double-membrane vesicles (DMVs) and other membrane structures.
Diede Oudshoorn +6 more
doaj +1 more source
Neonatal foal death due to infection with equine arteritis virus in Belgium [PDF]
This case report describes a small outbreak of neonatal foal death in Belgium due to infection with equine arteritis virus (EAV). The outbreak started with one foal suffering from acute dyspnea four days after birth.
Chiers, Koen +6 more
core
De Novo Initiation of RNA Synthesis by the Arterivirus RNA-Dependent RNA Polymerase [PDF]
ABSTRACT All plus-strand RNA viruses encode an RNA-dependent RNA polymerase (RdRp) that functions as the catalytic subunit of the viral replication/transcription complex, directing viral RNA synthesis in concert with other viral proteins and, sometimes, host proteins.
N. Beerens +6 more
openaire +3 more sources

