Results 91 to 100 of about 3,240 (195)

Recent advances in carbon quantum dots for virus detection, as well as inhibition and treatment of viral infection

Nano Convergence, 2022
In the last decade, carbon quantum dots (CQDs), as a novel class of carbon-based nanomaterials, have received increasing attention due to their distinct properties. CQDs are ultimately small nanoparticles with an average size below 10 nm, possessing high
Yuxiang Xue, Chenchen Liu, Gavin Andrews, Jinyan Wang, Yi Ge   +4 more
doaj   +1 more source

Isolation of Diverse Simian Arteriviruses Causing Hemorrhagic Disease

Emerging Infectious Diseases
Genetically diverse simian arteriviruses (simarteriviruses) naturally infect geographically and phylogenetically diverse monkeys, and cross-species transmission and emergence are of considerable concern.
Teressa M. Shaw, Samuel T. Dettle, Andres Mejia, Jennifer M. Hayes, Heather A. Simmons, Puja Basu, Jens H. Kuhn, Mitchell D. Ramuta, Cody J. Warren, Peter B. Jahrling, David H. O’Connor, Liupei Huang, Misbah Zaeem, Jiwon Seo, Igor I. Slukvin, Matthew E. Brown, Adam L. Bailey   +16 more
doaj   +1 more source

Unique epitopes recognized by monoclonal antibodies against HP-PRRSV: deep understanding of antigenic structure and virus-antibody interaction. [PDF]

PLoS ONE, 2014
Highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) is a member of the genus Arterivirus within the family Arteriviridae. N and GP3 proteins are the immunodominance regions of the PRRSV viral proteins.
Qian Wang, Jinmei Peng, Yan Sun, Jiazeng Chen, Tongqing An, Chaoliang Leng, Lin Li, Hongyuan Zhao, Xin Guo, Xinna Ge, Hanchun Yang, Zhijun Tian   +11 more
doaj   +1 more source

Early events in the generation of autophagosomes are required for the formation of membrane structures involved in hepatitis C virus genome replication [PDF]

, 2016
Hepatitis C virus (HCV) infection has been shown to induce autophagy but the mechanisms underpinning this process remain to be elucidated.
Bartlett, C, Harris, M, Mankouri, J, Mohl, B   +3 more
core   +1 more source

Arterivirus RNA-dependent RNA polymerase: Vital enzymatic activity remains elusive

Virology, 2016
All RNA viruses encode an RNA-dependent RNA polymerase (RdRp), which in arteriviruses is expressed as the C-terminal domain of nonstructural protein 9 (nsp9). Previously, potent primer-dependent RdRp activity has been demonstrated for the homologous polymerase subunit (nsp12) of the distantly related coronaviruses.
Lehmann, K.C., Gorbalenya, A.E., Snijder, E.J., Posthuma, C.C.   +3 more
openaire   +3 more sources

Heterodimerization of the Two Major Envelope Proteins Is Essential for Arterivirus Infectivity [PDF]

Journal of Virology, 2003
ABSTRACT The two major envelope proteins of arteriviruses, the membrane protein (M) and the major glycoprotein (GP 5 ), associate into a disulfide-linked heterodimer that is incorporated into the virion and has been assumed to be a prerequisite for virus assembly.
Eric J, Snijder, Jessika C, Dobbe, Willy J M, Spaan   +2 more
openaire   +2 more sources

MYH9 is an Essential Factor for Porcine Reproductive and Respiratory Syndrome Virus Infection [PDF]

, 2016
Porcine reproductive and respiratory syndrome (PRRS) caused by the PRRS virus (PRRSV) is an important swine disease worldwide. PRRSV has a limited tropism for certain cells, which may at least in part be attributed to the expression of the necessary ...
Du, Taofeng, Gao, Jiming, Goodfellow, Ian, Hiscox, Julian A, Huang, Baicheng, Liu, Hongliang, Liu, Ningning, Lv, Junhua, Mu, Yang, Nan, Yuchen, Sun, Yani, Syed, Shahid Faraz, Wang, Gang, Wang, Xiangpeng, Xiao, Shuqi, Xiao, Yihong, Zhang, Chong, Zhang, Gaiping, Zhao, Qin, Zhou, En-Min   +19 more
core   +1 more source

Cytokine profiles in pregnant gilts experimentally infected with porcine reproductive and respiratory syndrome virus and relationships with viral load and fetal outcome. [PDF]

, 2018
In spite of extensive research, immunologic control mechanisms against Porcine Reproductive and Respiratory Syndrome virus (PRRSv) remain poorly understood. Cytokine responses have been exhaustively studied in nursery pigs and show contradictory results.
ASHLEY, C., HARDING, J. C. S., LADINIG, A., LUNNEY, J. K., PLASTOW, G., SOUZA, C. J. H.   +5 more
core   +1 more source

Serological evidence for the presence of wobbly possum disease virus in Australia.

PLoS ONE, 2020
Wobbly possum disease virus (WPDV) is an arterivirus that was originally identified in common brushtail possums (Trichosurus vulpecula) in New Zealand, where it causes severe neurological disease.
Anita Tolpinrud, Simon M Firestone, Andrés Diaz-Méndez, Leanne Wicker, Stacey E Lynch, Magdalena Dunowska, Joanne M Devlin   +6 more
doaj   +1 more source

Impact of genotype 1 and 2 of porcine reproductive and respiratory syndrome viruses on interferon-α responses by plasmacytoid dendritic cells [PDF]

, 2013
Porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) infections are characterized by prolonged viremia and viral shedding consistent with incomplete immunity.
Baumann, Arnaud, Mateu de Antonio, Enrique María, Murtaugh, Michael P., Summerfield, Artur   +3 more
core   +3 more sources