Results 71 to 80 of about 3,240 (195)

Apoptosis in the lungs of pigs infected with porcine reproductive and respiratory syndrome virus and associations with the production of apoptogenic cytokines [PDF]

, 2003
International audienceApoptosis was studied in the lungs of pigs during an infection with a European strain of porcine reproductive and respiratory syndrome virus (PRRSV) and it was examined if cytokines were involved in the induction of apoptosis ...
Labarque, Geoffrey, Nauwynck, Hans, Pensaert, Maurice, Van Gucht, Steven, Van Reeth, Kristien   +4 more
core   +3 more sources

The Development of Unconventional Extrathymic Activated CD4+CD8+ T Cells in Chagas Disease

International Scholarly Research Notices, Volume 2013, Issue 1, 2013., 2013
The numbers of extrathymic CD4+CD8+ double‐positive (DP) T cells are augmented in various pathophysiological conditions, such as infectious diseases caused by intracellular pathogens, organs subjected to autoimmune attack and malignant tumors. The roles performed by extrathymic DP T cells are not clear, and it is not known how they are distributed in ...
Alexandre Morrot, Y.-H. Gan, H. Hisaeda, Y. Lai   +3 more
wiley   +1 more source

Interplay between Interferon-Mediated Innate Immunity and Porcine Reproductive and Respiratory Syndrome Virus

Viruses, 2012
Innate immunity is the first line of defense against viral infection, and in turn, viruses have evolved to evade host immune surveillance. As a result, viruses may persist in host and develop chronic infections. Type I interferons (IFN-α/β) are among the
Mingyuan Han, Chiyong Kim, Dongwan Yoo, Jay G. Calvert, Yan Sun   +4 more
doaj   +1 more source

A WUR SNP is associated with European Porcine Reproductive and Respiratory Virus Syndrome resistance and growth performance in pigs [PDF]

, 2016
Porcine reproductive and respiratory syndrome (PRRS) causes decreased reproductive performance and respiratory problems in pigs. The goals of the current study were 1) to examine whether individual variation applies to infection with PRRSV European ...
Abella Falcó, Glòria, Armengol Gelonch, Ramon, Estany Illa, Joan, Fraile Sauce, Lorenzo José, Moradell, Luís, Nogareda, Carmina, Novell, Elena, Pena i Subirà, Ramona Natacha, Tarancón, Vicens, Vidal, Albert   +9 more
core   +2 more sources

Applications of the Phytomedicine Echinacea purpurea (Purple Coneflower) in Infectious Diseases

BioMed Research International, Volume 2012, Issue 1, 2012., 2012
Extracts of Echinacea purpurea (EP, purple coneflower) have been used traditionally in North America for the treatment of various types of infections and wounds, and they have become very popular herbal medicines globally. Recent studies have revealed that certain standardized preparations contain potent and selective antiviral and antimicrobial ...
James B. Hudson, Munekazu Iinuma
wiley   +1 more source

Efficient −2 frameshifting by mammalian ribosomes to synthesize an additional arterivirus protein [PDF]

Proceedings of the National Academy of Sciences, 2012
Programmed −1 ribosomal frameshifting (−1 PRF) is a gene-expression mechanism used to express many viral and some cellular genes. In contrast, efficient natural utilization of −2 PRF has not been demonstrated previously in eukaryotic systems.
Fang, Y., Treffers, E.E., Li, Y.H., Tas, A., Sun, Z., Meer, Y. van der, Ru, A.H. de, Veelen, P.A. van, Atkins, J.F., Snijder, E.J., Firth, A.E.   +10 more
openaire   +3 more sources

The Interaction between Nidovirales and Autophagy Components

Viruses, 2017
Autophagy is a conserved intracellular catabolic pathway that allows cells to maintain homeostasis through the degradation of deleterious components via specialized double-membrane vesicles called autophagosomes.
Yingying Cong, Pauline Verlhac, Fulvio Reggiori   +2 more
doaj   +1 more source

The Infection Properties of Trionyx sinensis Hemorrhagic Syndrome Virus and the Antiviral Effect of Curcumin In Vivo

Animals, 2023
Trionyx sinensis hemorrhagic syndrome virus (TSHSV) is an aquatic arterivirus causing a high mortality rate for T. sinensis (Chinese soft-shelled turtle), but the detailed infection properties of TSHSV are unclear, and no effective treatment is available.
Jinbiao Jiao, Jiayun Yao, Feng Lin, Xuemei Yuan, Lei Huang, Jing Chen, Xianqi Peng, Haiqi Zhang, Shengqi Su   +8 more
doaj   +1 more source

Autophagy: New Questions from Recent Answers

International Scholarly Research Notices, Volume 2012, Issue 1, 2012., 2012
Macroautophagy (hereafter autophagy) is currently one of the areas of medical life sciences attracting a great interest because of its pathological implications and therapy potentials. The discovery of the autophagy-related genes (ATGs) has been the key event in this research field because their study has led to the acquisition of new knowledge about ...
Fulvio Reggiori, T. Hellwig-Bürgel, A. J. Molenaar, A. Montecucco   +3 more
wiley   +1 more source

Porcine reproductive and respiratory syndrome virus infection triggers autophagy via ER stress-induced calcium signaling to facilitate virus replication.

PLoS Pathogens, 2023
Calcium (Ca2+), a ubiquitous second messenger, plays a crucial role in many cellular functions. Viruses often hijack Ca2+ signaling to facilitate viral processes such as entry, replication, assembly, and egress.
Feifei Diao, Chenlong Jiang, Yangyang Sun, Yanni Gao, Juan Bai, Hans Nauwynck, Xianwei Wang, Yuanqi Yang, Ping Jiang, Xing Liu   +9 more
doaj   +1 more source