Results 51 to 60 of about 3,240 (195)

Proteolytic Processing of the Arterivirus Replicase [PDF]

, 1995
Arteriviruses are enveloped positive-stranded RNA viruses which belong to the so-called ‘coronaviruslike superfamily’1,2,3,4. At present, the arterivirus group is comprised of equine arteritis virus (EAV, the prototype of the group), lactate dehydrogenase-elevating virus (LDV), porcine reproductive and respiratory syndrome virus (PRRSV, also known as ...
E, Snijder, A L, Wassenaar, J A, Den Boon, W J, Spaan   +3 more
openaire   +2 more sources

Transcriptome Analysis Reveals Dynamic Gene Expression Profiles in Porcine Alveolar Macrophages in Response to the Chinese Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus

BioMed Research International, Volume 2018, Issue 1, 2018., 2018
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most economically important swine pathogens and causes reproductive failure in sows and respiratory disease in growing pigs. PRRSV mainly infects porcine alveolar macrophages (PAMs), leading to the subversion of innate and adaptive immunity of pigs.
Nanfang Zeng, Cong Wang, Siyu Liu, Qi Miao, Lei Zhou, Xinna Ge, Jun Han, Xin Guo, Hanchun Yang, Yanjin Zhang   +9 more
wiley   +1 more source

Arterivirus Nsp1 modulates the accumulation of minus-strand templates to control the relative abundance of viral mRNAs. [PDF]

PLoS Pathogens, 2010
The gene expression of plus-strand RNA viruses with a polycistronic genome depends on translation and replication of the genomic mRNA, as well as synthesis of subgenomic (sg) mRNAs.
Danny D Nedialkova, Alexander E Gorbalenya, Eric J Snijder   +2 more
doaj   +1 more source

Severe acute respiratory syndrome coronavirus nonstructural proteins 3, 4, and 6 induce double-membrane vesicles [PDF]

, 2013
Coronaviruses (CoV), like other positive-stranded RNA viruses, redirect and rearrange host cell membranes for use as part of the viral genome replication and transcription machinery.
Baliji, Barretto, Beachboard, Centers for Disease Control and Prevention, Chan, Clementz, Cornillez-Ty, Cottam, de Groot, den Boon, den Boon, Drosten, Gadlage, Giansanti, Gosert, Hagemeijer, Hagemeijer, Hagemeijer, Harcourt, Imbert, Kanjanahaluethai, Kanjanahaluethai, Knoops, Ksiazek, Miller, Netherton, Neuman, Oostra, Oostra, Pasternak, Pedersen, Perlman, Posthuma, Poutanen, Prentice, Prentice, Reggiori, Salonen, Sawicki, Schmidt, Snijder, Snijder, Snijder, Sparks, Stertz, Suhy, Ulasli, Ulferts, van den Worm, Zaki, Ziebuhr   +50 more
core   +1 more source

Expression of the Heterotrimeric GP2/GP3/GP4 Spike of an Arterivirus in Mammalian Cells

Viruses, 2022
Equine arteritis virus (EAV), an enveloped positive-strand RNA virus, is an important pathogen of horses and the prototype member of the Arteiviridae family.
Anna Karolina Matczuk, Minze Zhang, Michael Veit, Maciej Ugorski   +3 more
doaj   +1 more source

Zoonotic potential of simian arteriviruses [PDF]

, 2015
Wild nonhuman primates are immediate sources and long-term reservoirs of human pathogens. However, ethical and technical challenges have hampered the identification of novel blood-borne pathogens in these animals.
Apetrei, Cristian, Bailey, Adam L, Freimer, Nelson B, Friedrich, Thomas C, Goldberg, Tony L, Jasinska, Anna J, Jolly, Clifford J, Kuhn, Jens H, Lauck, Michael, Marx, Preston A, O\u27Connor, David H, Phillips-Conroy, Jane E, Rogers, Jeffrey, Sibley, Samuel D   +13 more
core   +2 more sources

Structure and Genetic Analysis of the Arterivirus Nonstructural Protein 7α [PDF]

Journal of Virology, 2011
ABSTRACT Arterivirus replicase polyproteins are cleaved into at least 13 mature nonstructural proteins (nsps), and in particular the nsp5-to-nsp8 region is subject to a complex processing cascade. The function of the largest subunit from this region, nsp7, which is further cleaved into nsp7α and nsp7β, is unknown.
Manolaridis, I., Gaudin, C., Posthuma, C.C., Zevenhoven-Dobbe, J.C., Imbert, I., Canard, B., Kelly, G., Tucker, P.A., Conte, M.R., Snijder, E.J.   +9 more
openaire   +4 more sources

Porcine Reproductive and Respiratory Syndrome Virus: Origin Hypothesis

Emerging Infectious Diseases, 2003
Porcine reproductive and respiratory syndrome is a serious swine disease that appeared suddenly in the midwestern United States and central Europe approximately 14 years ago; the disease has now spread worldwide. In North America and Europe, the syndrome
Peter G.W. Plagemann
doaj   +1 more source

The complex co-translational processing of glycoprotein GP5 of type 1 porcine reproductive and respiratory syndrome virus [PDF]

, 2017
GP5 and M, the major membrane proteins of porcine reproductive and respiratory syndrome virus (PRRSV), are the driving force for virus budding and a target for antibodies.
Kaufer, Susanne, Krause, Eberhard, Nauwynck, Hans, Neumann, Sara A, Peibst, Bernadett, Thaa, Bastian, Veit, Michael   +6 more
core   +2 more sources

Comparison of Host Immune Responses to Homologous and Heterologous Type II Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Challenge in Vaccinated and Unvaccinated Pigs

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
Porcine reproductive and respiratory syndrome (PRRS) is a high‐consequence animal disease with current vaccines providing limited protection from infection due to the high degree of genetic variation of field PRRS virus. Therefore, understanding host immune responses elicited by different PRRSV strains will facilitate the development of more effective ...
X. Li, A. Galliher-Beckley, L. Pappan, B. Trible, M. Kerrigan, A. Beck, R. Hesse, F. Blecha, J. C. Nietfeld, R. R. Rowland, J. Shi, Denis Archambault   +11 more
wiley   +1 more source