Results 21 to 30 of about 3,240 (195)
The biological functions of PRRSV nonstructural protein NSP2 in viral infection and replication and its role in host regulatory mechanisms [PDF]
Frontiers in Veterinary SciencePorcine reproductive and respiratory syndrome virus (PRRSV) is a single-stranded, positive-sense arterivirus that causes reproductive and respiratory disorders in sows.
Zhenzhen Zheng +4 more
doaj +2 more sources
The full-length nsp2 replicase contributes to viral assembly in highly pathogenic PRRSV-2 [PDF]
Journal of VirologyPorcine reproductive and respiratory syndrome viruses (PRRSVs) are significant pathogens that affect the global swine industry. Its virions consist of a central core composed of nucleocapsid (N) protein, surrounded by multiple distinct viral envelope ...
Yuan-Zhe Bai +12 more
doaj +2 more sources
Mediators of Inflammation, 2014 Porcine reproductive and respiratory syndrome virus (PRRSV) is an Arterivirus that has been devastating the swine industry worldwide since the late 1980s. Previous studies have reported that PRRSV infection induced the production of IL-1β.
Jing Bi +9 more
doaj +2 more sources
Development of GFP-expressing infectious clones for PRRSV using TAR cloning for antiviral drug screening [PDF]
npj VirusesPorcine reproductive and respiratory syndrome virus (PRRSV), an Arteriviridae family enveloped RNA virus, is a major swine pathogen. Using yeast transformation-associated recombination (TAR) cloning, we efficiently generated infectious PRRSV and GFP ...
Minze Zhang +3 more
doaj +2 more sources
Viruses, 2012 Regulatory T cells (T<sub>regs</sub>) are a subset of T cells that are responsible for maintaining peripheral immune tolerance and homeostasis.
Tanya LeRoith
exaly +3 more sources
eLife, 2022 The efficiency with which ribosomes shift reading frames when decoding viral RNA may change over the course of an infection.
Martina M Yordanova, Pavel V Baranov
doaj +1 more source
Nutraceuticals and COVID‐19: A mechanistic approach toward attenuating the disease complications
Journal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022 Abstract Nutraceuticals have emerged as potential compounds to attenuate the COVID‐19 complications. Precisely, these food additives strengthen the overall COVID treatment and enhance the immunity of a person. Such compounds have been used at a large scale, in almost every household due to their better affordability and easy access.
Keshav Raj Paudel +19 more
wiley +1 more source
Advanced NanoBiomed Research, Volume 2, Issue 10, October 2022., 2022 Heparan sulfate analogue (sodium 3‐mercaptopropane sulfonate, MPS) modified MXene nanocomposites (Ti3C2‐Au‐MPS) are successfully synthesized, which can strongly inhibit porcine reproductive and respiratory syndrome virus (PRRSV) and severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pseudovirus.
Ting Tong +3 more
wiley +1 more source
Recent insights into the structure and function of coronavirus ribonucleases
FEBS Open Bio, Volume 12, Issue 9, Page 1567-1583, September 2022., 2022 Coronaviruses encode two ribonucleases: Nsp14, an exonuclease, and Nsp15, an endonuclease. This review covers the latest structures of SARS‐CoV‐2 Nsp14 and Nsp15 and discusses insights into nuclease functions and progress towards therapeutic inhibitors. The viral particle was generated using BioRender.
Meredith N. Frazier +4 more
wiley +1 more source
Escaping the Lion’s Den: redirecting autophagy for unconventional release and spread of viruses
The FEBS Journal, Volume 288, Issue 13, Page 3913-3927, July 2021., 2021 RNA virus progenies undergo secretion and spread via multiple pathways. We highlight recent evidence on the autophagosome‐derived unconventional route. The inner membrane of these organelles can either disintegrate to release free virions or stay intact to release populations of virions in membrane‐bound forms, which are then internalized into ...
Qi Wen Teo +2 more
wiley +1 more source