Recent Progress in Studies of Arterivirus- and Coronavirus-Host Interactions [PDF]
Viruses, 2012 Animal coronaviruses, such as infectious bronchitis virus (IBV), and arteriviruses, such as porcine reproductive and respiratory syndrome virus (PRRSV), are able to manifest highly contagious infections in their specific native hosts, thereby arising in ...
Ding Xiang Liu +2 more
exaly +5 more sources
Suppression of TRIM19 by arterivirus nonstructural protein 1 promotes viral replication [PDF]
Virus ResearchTripartite motif (TRIM)-containing proteins are a family of regulatory proteins that can participate in the induction of antiviral cytokines and antagonize viral replication. Promyelocytic leukemia (PML) protein is known as TRIM19 and is a major scaffold
Chia-Ming Su +5 more
doaj +4 more sources
Calcium-mediated mitochondrial fission and mitophagy drive glycolysis to facilitate arterivirus proliferation. [PDF]
PLoS PathogensMitochondria, recognized as the "powerhouse" of cells, play a vital role in generating cellular energy through dynamic processes such as fission and fusion.
Zhe Sun +10 more
doaj +4 more sources
Animal Arterivirus Infections [PDF]
BioMed Research International, 2014 BioMed Research International, Volume 2014, Issue 1, 2014.
Denis Archambault +4 more
wiley +3 more sources
The SHFV nsp2 and nucleocapsid proteins recruit G3BP1 to sites of viral replication, but stress granules are not induced by the infection [PDF]
Journal of VirologyStress granules (SGs) are dynamic, cytoplasmic foci that form in response to environmental stresses, including viral infections, and function to restore cellular homeostasis by regulating mRNA translation, storage, and decay.
Ayisha A. Lavender +6 more
doaj +2 more sources
Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis. [PDF]
PLoS Pathogens, 2023 Deubiquitination of cellular substrates by viral proteases is a mechanism used to interfere with host cellular signaling processes, shared between members of the coronavirus- and arterivirus families.
Ben A Bailey-Elkin +9 more
doaj +2 more sources
Identification and characterization of two putative novel genera of arteriviruses in shrews and rats [PDF]
Frontiers in MicrobiologyIntroductionCertain arteriviruses causing severe diseases in domestic animals, such as porcine respiratory and reproductive syndrome viruses, could originate through viral spillover, and simian arteriviruses pose threats to public health through viral ...
Xiu Wang +7 more
doaj +2 more sources
Clinical Characterization of Host Response to Simian Hemorrhagic Fever Virus Infection in Permissive and Refractory Hosts: A Model for Determining Mechanisms of VHF Pathogenesis [PDF]
Viruses, 2019 Simian hemorrhagic fever virus (SHFV) causes a fulminant and typically lethal viral hemorrhagic fever (VHF) in macaques (Cercopithecinae: Macaca spp.) but causes subclinical infections in patas monkeys (Cercopithecinae: Erythrocebus patas).
Joseph P. Cornish +18 more
doaj +3 more sources
Comparative analysis of newly identified rodent arteriviruses and porcine reproductive and respiratory syndrome virus to characterize their evolutionary relationships [PDF]
Frontiers in Veterinary Science, 2023 Porcine reproductive and respiratory syndrome virus (PRRSV) has caused huge economic losses for the global pig industry, but its origins and evolution remain a mystery.
Zhuang-Yan Zhao +6 more
doaj +2 more sources
Ineffectual immunity in a resurrected mouse model of persistent viremia [PDF]
Journal of VirologyViruses that establish persistent (i.e., chronic) infections have evolved sophisticated strategies to avoid clearance by the host immune system. This is particularly true for viruses that infect immunocompetent mammals and sustain high infectious burdens
Kylie Nennig +3 more
doaj +2 more sources