Results 141 to 150 of about 40,278 (255)

Angina pectoris induced by sublingual nifedipine

, 1999
This report describes the case of a 44-year-old man with angina pectoris caused by sublingual nifedipine. He developed chest pain after receiving 5mg sublingual nifedipine for treatment of hypertensive encephalopathy, and his electrocardiogram showed ...
Ishibashi, Yutaka, Shimada, Toshio, Asanuma, Toshihiko, Sano, Kazuya, Murakami, Yo, Katoh, Harumi, Takahashi, Nobuyuki   +6 more
core   +1 more source

Brain Penetrant Calcium Channel Blockers Were Not Associated With Reduced Alcohol Consumption: Converging Results From Two Large Independent Cohort Studies Using Electronic Health Records

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.
ABSTRACT Purpose Alcohol use disorder (AUD) remains a major public health problem, with few effective treatments. L‐type calcium channel blockers (LTCCBs) have genetic and preclinical support as potential treatments for AUD. Methods We evaluated whether brain penetrant (BP)‐LTCCBs are associated with reduced alcohol consumption in two preregistered ...
Christopher T. Rentsch, Vanessa A. Palzes, Mingjian Shi, Michael R. Setzer, Samantha G. Malone, Andrea H. Kline‐Simon, Emma L. Winterlind, Lorenzo Leggio, Vincent Lo Re III, David A. Fiellin, John Tazare, Mehdi Farokhnia, Stacy Sterling, Henry R. Kranzler, Joshua C. Gray   +14 more
wiley   +1 more source

The Use of Intravenous Clonidine in Postoperative Pain Management: A Scoping Review

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background Clonidine, an alpha‐2 receptor agonist, has been explored as a potential analgesic in postoperative pain management, but its efficacy and safety profile remain unclear. The aim of this scoping review was to present the evidence on the use of intravenous clonidine in postoperative pain management.
Tórálvur Mohr, Emma Atsuko Tsuchiya, Mette Krag, Bitten Dybdal, Johan Heiberg   +4 more
wiley   +1 more source

Rapid recurrence of pulmonary hypertension following cessation of nifedipine.

, 2012
In a young woman with primary pulmonary hypertension, treatment with low-dose nifedipine resulted in resolution of symptoms and of tricuspid regurgitation.
Gallagher, M M, Hart, C M, Vaughan, C J, Fennell, W H   +3 more
core  

The Binding of Fibroblast Growth Factor 23 (FGF23) to FGF Receptor‐αKlotho Complex Increases Sinoatrial Electrical Activity

Acta Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim This study aims to investigate whether the Fibroblast Growth Factor 23 (FGF23) modulates the electrical activity of sinoatrial (SAN) cells. The canonical function of FGF23 is to regulate body phosphorus and calcium homeostasis by activating the FGF1 receptors (FGFR1)/α‐Klotho complex in the kidney and parathyroid glands.
Giorgia Bertoli, Patrizia Benzoni, Serena Canzolino, David Molla, Raffaella Milanesi, Chiara Piantoni, Makoto Kuro‐o, Carmen Delgado, Gema Ruiz‐Hurtado, Mirko Baruscotti, Annalisa Bucchi   +10 more
wiley   +1 more source

Framework for headache management in pediatric patients with stroke and cerebrovascular lesions: A narrative review

Headache: The Journal of Head and Face Pain, Volume 66, Issue 9, Page 2138-2155, October 2026.
Abstract Objective To present a practical, evidence‐based framework for the management of headache disorders in pediatric patients with prior stroke or underlying cerebral vascular lesions, with particular attention to safety and efficacy of pharmacologic and non‐pharmacologic therapies.
Allison C. Hyland, Samuel J. Belfer, Christine K. Fox, Samantha L. Irwin, Rachel Vassar, Ann Oh, Sruthi Ilangovan, Amy A. Gelfand   +7 more
wiley   +1 more source

Identification and Validation of Biomarkers Associated With Mitochondrial Dynamics in Preeclampsia

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 10, October 2026.
ABSTRACT Aim Despite studies highlighting mitochondrial dynamics in preeclampsia (PE), the regulatory mechanisms of mitochondrial dynamics‐related genes (MD‐RGs) in PE remain unclear. This study aims to explore these mechanisms. Methods PE‐related datasets (GSE10588 and GSE98224) and 23 MD‐RGs were used.
Xueying Liu, Mei Liu, Chuanyan Chen, Xiaoyan Gao, Zhenru Xu, Wenxiao Gao, Haining Qi, Qi Li, Jianhong Xing   +8 more
wiley   +1 more source

Comparative effectiveness of amlodipine versus nifedipine prescribed at discharge in patients with ischemic stroke or transient ischemic attack: A nationwide 5-year follow-up registry study. [PDF]

PLoS Med
Li X, Xia X, Gao M, Xu Q, Zhang Y, Jing J, Zhai Y, Meng X, Wang A.   +8 more
europepmc   +1 more source

Determining properties of human‐induced pluripotent stem cell‐derived cardiomyocytes using spatially resolved electromechanical metrics

The Journal of Physiology, Volume 604, Issue 19, Page 8069-8099, 1 October 2026.
Abstract figure legend In this study, we use human‐induced pluripotent stem cell‐derived cardiomyocyte (hiPSC‐CM) experiments and computational modelling to identify the mechanism of action of drug compounds. In the hiPSC‐CM experiments, optical measurements of cell collections are recorded in the baseline case and after drug exposure.
Karoline Horgmo Jæger, Verena Charwat, Kevin E. Healy, Samuel Wall, Aslak Tveito   +4 more
wiley   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, Volume 604, Issue 19, Page 8141-8166, 1 October 2026.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source