Results 131 to 140 of about 40,278 (255)
The effects of nifedipine on myocardial blood flow and contraction during ischemia in the dog.
Nifedipine has been proposed as an agent to preserve viability and function of ischemic myocardium. We studied 23 open-chest dogs that underwent carotid-to-left anterior coronary artery perfusion with flow probe and perfusion pressure monitoring. Segment
W S Weintraub +5 more
core +1 more source
Background/Objectives: This study focused on developing an organic solvent-free formulation of phytantriol-based cubosomes for nifedipine delivery.
Lorena Almeida Lima +4 more
doaj +1 more source
Hemodynamic and humoral interactions between captopril and nifedipine.
Nine patients with uncomplicated essential hypertension received, according to a randomized sequence, captopril (25 mg three times daily), nifedipine (10 mg three times daily), and both drugs for 1 week, with each treatment period separated by a 1-week ...
Pisani R +6 more
core
Nifedipine-induced Hyperglycaemia in an Infant: Case Report.
This case report describes reversible hyperglycaemia in a severely ill six-month old Saudi boy treated with nifedipine for hypertension. Hyperglycaemia became manifest on the second day of treatment with nifedipine and was not dose-related.
Daama, Saad Al +13 more
core +1 more source
Aim Many women take medications during pregnancy. However, the risk to the fetus from most medications is uncertain. Congenital anomalies are one of the leading causes of infant death and contribute to long‐term disability. Signal detection methods can be used to systematically identify possible medication–anomaly associations that require further ...
Hannah Johnson +22 more
wiley +1 more source
Pharmacokinetics of nifedipine in humans
Nifedipine is a dihydropyridine calcium antagonist which is widely used in the treatment of hypertension and ischaemic heart disease. After oral administration, nifedipine undergoes extensive first-pass metabolism and shows wide interindividual ...
Ahsan, Chowdhury Hafizul
core
ABSTRACT A young, physically active patient with no cardiac symptoms presented with abdominal pain and was found, through incidental findings of elevated BNP, cardiomegaly, and new ECG changes, to have severe HFrEF with a left ventricular apical thrombus. Early cardiac evaluation changed management and led to complete thrombus resolution.
Maryam Othman Alarfaj +6 more
wiley +1 more source
Small Molecule Therapeutic Approaches With a Greater Focus on Hearing Loss: A Review
ABSTRACT Background and Aims Hearing loss (HL) is one of the most common sensory impairments worldwide and has substantial effects on quality of life and daily functioning. Although cochlear implants and hearing aids have markedly improved the management of hearing impairment, these devices do not directly address the underlying pathogenic mechanisms ...
Maryam Naghinejad +5 more
wiley +1 more source
ABSTRACT Background and Aim Drug–drug interactions (DDIs) occur when the pharmacological effect of one medication is altered by the concurrent administration of another, potentially leading to reduced therapeutic efficacy or increased risk of adverse effects.
Brenda Koech, Ermias Terefe
wiley +1 more source
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source

