Results 161 to 170 of about 66,702 (306)
Prediction of favourable responses to long term vasodilator treatment of pulmonary hypertension by short term administration of epoprostenol (prostacyclin) or nifedipine. [PDF]
A. Rozkovec +5 more
openalex +1 more source
ABSTRACT The P‐STS human ileal enteroendocrine tumor cell line responds with an increase in intracellular calcium and serotonin secretion to acetylcholine and histamine. Here we show that the cells react similarly to the protease‐activated receptor 2 (PAR2) agonists trypsin and SLIGRL‐NH2 peptide.
Beatrix Pfanzagl, Erika Jensen‐Jarolim
wiley +1 more source
The mechanism of action of calcium antagonists on arrhythmias in early myocardial ischaemia: studies with nifedipine and DHM9 [PDF]
Michael J. Curtis, Michael Walker
openalex +1 more source
ABSTRACT Aim To elucidate the molecular mechanism of cold sensing by visceral sensory endings, a side‐by‐side characterization of cold‐sensitive (CS) neurons in adult mouse trigeminal (TG) and vagal ganglia (VG) was performed. Methods A combination of physiological, pharmacological, molecular, and genetic tools was employed on trigeminal and vagal ...
Katharina Gers‐Barlag +4 more
wiley +1 more source
Background and Purpose Hydrogen sulphide (H2S) is synthesised endogenously through cystathionine β‐synthase (CBS), cystathionine γ‐lyase (CSE) and 3‐mercaptopyruvate sulfurtransferase (3‐MST). Although exogenous H2S is known to produce vasodilatation, the vascular effect of H2S produced through 3‐MST is unknown. In this study, we demonstrate the effect
Maha Almaheize +7 more
wiley +1 more source
Drug‐induced gingival overgrowth involves dysregulation of intracellular collagen degradation. The mechanisms that are involved in the regulation of lysosomal collagenolytic activity are poorly understood. Here, we focus on how cathepsins, Rabs, and V‐ATPases regulate intracellular collagen degradation and, in particular, the vesicular trafficking and ...
Wing Hei Wong +3 more
wiley +1 more source

