Results 161 to 170 of about 67,449 (286)
Alzheimer's &Dementia, Volume 21, Issue S5, December 2025.Abstract Background We previously identified Sildenafil (a phosphodiesterase type 5 (PDE5) inhibitor) as a candidate drug in Alzheimer’s Disease (AD) using an in silico network medicine approach. However, the clinically meaningful effect size and mechanism‐of‐action of sildenafil in AD treatment is still unclear.
Yichen Li +4 more
wiley +1 more source
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.Involvement of Ca2+ channels in boldine‐induced vascular relaxation. ABSTRACT The regulation of vascular tone plays a fundamental role in blood pressure homeostasis and still represents a significant challenge in clinical practice. Boldine, a naturally occurring alkaloid from Peumus boldus, has emerged as a compound of interest due to its therapeutic ...
Martina Odebrecht Cavichiolo +3 more
wiley +1 more source
Pakistan Armed Forces Medical Journal, 2018 Objective: To compare the outcome of oral Nifedipine & intravenous Labetalol in severe pregnancy induced hypertension in terms of time taken to achieve the target blood pressure. Study Design: Randomized controlled trial.
Riffat Sarwar +3 more
doaj
Are propranolol and nifedipine synergistic in angina pectoris? [letter] [PDF]
, 1982 BC Campbell
openalex +1 more source
Thai Journal of Obstetrics and Gynaecology, 2009 Objective: To compare the efficacy, success rate, maternal and fetal complications of progesterone and nifedipine administration as a tocolytic agent to women with threatened preterm labour. Study Design : A randomized controlled trial.
Saifon Chawanpaiboon +4 more
doaj
CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.The combined ACD use and elevated NfL levels jointly increased the risk of incident dementia. Older adults with both high ACDs exposure and high NfL levels exhibited a significantly higher risk of dementia compared to low‐burden counterparts. ABSTRACT Aims Anticholinergic drugs (ACDs) and the neurodegeneration biomarker neurofilament light chain (NfL ...
Danyi Chi +6 more
wiley +1 more source
Health Science Reports, Volume 8, Issue 12, December 2025.ABSTRACT Background and Aims Preterm premature rupture of membranes (PPROM), a complication in approximately 4.5% of pregnancies, is a leading cause of preterm birth and significant perinatal morbidity. A substantial body of evidence implicates vaginal dysbiosis a departure from a healthy, Lactobacillus‐dominant microbiome in the pathogenesis of PPROM.
Maryam Alikamali +4 more
wiley +1 more source
Long-acting nifedipine in the management of the hypertensive patient
Vascular Health and Risk Management, 2008 Morgan E Snider1, Donald S Nuzum2, Angie Veverka21Virginia Commonwealth University Health Systems Richmond, VA USA; 2Wingate University School of Pharmacy Wingate, NC USAAbstract: Hypertension is a global condition affecting billions worldwide.
Morgan E Snider +2 more
doaj
Ca2+ Channel β Subunits Did Not Contribute to the Low Affinity of Cav1.3 to Nifedipine
, 2011 Mina Ochiai +5 more
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