Results 161 to 170 of about 66,702 (306)

Protease‐Activated Receptor 2 Activation Provokes an Increase in Intracellular Calcium and Serotonin Secretion in a Human Enteroendocrine Cell Line

open access: yesCell Biochemistry and Function, Volume 43, Issue 11, November 2025.
ABSTRACT The P‐STS human ileal enteroendocrine tumor cell line responds with an increase in intracellular calcium and serotonin secretion to acetylcholine and histamine. Here we show that the cells react similarly to the protease‐activated receptor 2 (PAR2) agonists trypsin and SLIGRL‐NH2 peptide.
Beatrix Pfanzagl, Erika Jensen‐Jarolim
wiley   +1 more source

Nifedipin [PDF]

open access: yes, 2020
openaire   +1 more source

Transduction Mechanisms for Cold Temperature in Mouse Trigeminal and Vagal Ganglion Neurons Innervating Different Peripheral Organs

open access: yesActa Physiologica, Volume 241, Issue 11, November 2025.
ABSTRACT Aim To elucidate the molecular mechanism of cold sensing by visceral sensory endings, a side‐by‐side characterization of cold‐sensitive (CS) neurons in adult mouse trigeminal (TG) and vagal ganglia (VG) was performed. Methods A combination of physiological, pharmacological, molecular, and genetic tools was employed on trigeminal and vagal ...
Katharina Gers‐Barlag   +4 more
wiley   +1 more source

Effect of 3‐mercaptopyruvate sulfurtransferase (3‐MST) inhibitors on contractile responses in porcine coronary artery

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 22, Page 5453-5468, November 2025.
Background and Purpose Hydrogen sulphide (H2S) is synthesised endogenously through cystathionine β‐synthase (CBS), cystathionine γ‐lyase (CSE) and 3‐mercaptopyruvate sulfurtransferase (3‐MST). Although exogenous H2S is known to produce vasodilatation, the vascular effect of H2S produced through 3‐MST is unknown. In this study, we demonstrate the effect
Maha Almaheize   +7 more
wiley   +1 more source

High Altitude Pulmonary Edema [PDF]

open access: yes, 2020
Charnigo, Aubri, Yee, Jennifer
core  

New Mechanisms for Regulation of Intracellular Collagen Degradation in Fibrotic Lesions of Periodontal Tissues

open access: yesThe FASEB Journal, Volume 39, Issue 20, 31 October 2025.
Drug‐induced gingival overgrowth involves dysregulation of intracellular collagen degradation. The mechanisms that are involved in the regulation of lysosomal collagenolytic activity are poorly understood. Here, we focus on how cathepsins, Rabs, and V‐ATPases regulate intracellular collagen degradation and, in particular, the vesicular trafficking and ...
Wing Hei Wong   +3 more
wiley   +1 more source

Nifedipine in cardiac operations

open access: bronze, 1982
M Nijsen-Karelse   +2 more
openalex   +1 more source

Home - About - Disclaimer - Privacy