Results 31 to 40 of about 27,204 (207)

Case‐malformed signal detection and prioritisation using EUROmediCAT data for pharmacovigilance in pregnancy

British Journal of Clinical Pharmacology, EarlyView.
Aim Many women take medications during pregnancy. However, the risk to the fetus from most medications is uncertain. Congenital anomalies are one of the leading causes of infant death and contribute to long‐term disability. Signal detection methods can be used to systematically identify possible medication–anomaly associations that require further ...
Hannah Johnson, Helen Dolk, Maria Loane, Christine Damase‐Michel, Joanne Given, Hedvig Nordeng, Jorieke E. H. Bergman, Iain Carey, Elly Den Hond, Ester Garne, Florence Rouget, Lea Bruneau, Isabelle Monier, Anke Rissmann, Mary O'Mahony, Miriam Gatt, Renée Lutke, Joanna Sichitiu, Elisa Ballardini, Alessio Coi, Clara Cavero Carbonell, David Tucker, Joan Morris   +22 more
wiley   +1 more source

Nifedipine Alone or Combined with Sildenafil Citrate for Management of Threatened Preterm Labour [PDF]

Al-Azhar International Medical Journal
Background: Preterm labor (PTL) is defined as the delivery of a baby after twenty weeks of gestation and prior to the completion of thirty-seven weeks of gestation.Aim: To determine whether the tocolytic effect of nifedipine in combination with ...
doaj   +1 more source

SUSTAINED-RELEASE FORMULATIONS FOR NIFEDIPINE

Zagazig Journal of Pharmaceutical Sciences, 1993
Three formulae of nifedipine sustained release granules were tried, each containing 10% of the drug. The former one was composed of nifedipine, lactose and PVP 40000, and prepared adopting moist granulation technique. In the second formula, the drug, PEG
Mohamed Fetouh
doaj   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Nifedipine and indomethacin in preventing preterm labor under 32 gestational weeks

Gülhane Tıp Dergisi, 2022
Aims:This study compared nifedipine and indomethacin treatments, commonly used tocolytic agents, in terms of efficacy and maternal side effects.Methods:This retrospective study included pregnant women spontaneous preterm labor between 24 and 32 weeks of ...
Gülşah Dağdeviren, Münevver Aksoy, Özge Yücel Çelik, Ayşe Keleş, Şevki Çelen, Ali Turhan Çağlar   +5 more
doaj   +1 more source

Cost‐effectiveness of a randomized controlled trial comparing low‐dose aspirin to placebo for the prevention of recurrent preterm birth

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 399-407, April 2025.
Abstract To assess the cost‐effectiveness of low‐dose aspirin compared to placebo for the prevention of recurrent preterm birth from a healthcare perspective. This was a cost‐effectiveness analysis alongside a multicenter, randomized, double‐blinded, placebo‐controlled trial.
Anadeijda J. E. M. C. Landman, Hana M. Broulikova, Laura Visser, Tobias A. J. Nijman, Marieke A. C. Hemels, Karin C. Vollebregt, Elisabeth M. A. Boormans, Henk A. Bremer, Esther Tuinman, Josje Langenveld, Flip van der Made, Robbert J. P. Rijnders, Huib A. A. M. van Vliet, Liv M. Freeman, Roel de Heus, Judith Blaauw, Ineke Krabbendam, Rafli van de Laar, Marieke F. G. Verberg, Hubertina C. J. Scheepers, Ben W. Mol, Christianne J. M. de Groot, Martijn A. Oudijk, Judith E. Bosmans, Marjon A. de Boer   +24 more
wiley   +1 more source

Oral nifedipine may be a preferential option for treating acute severe hypertension during pregnancy: a meta-analysis

Hypertension in Pregnancy, 2023
Aim To compare oral nifedipine and intravenous labetalol in the treatment of acute severe hypertension in pregnancy (SHP). Methods The primary outcomes were the required time to achieve target blood pressure (RTATBP), systolic blood pressure (SBP) and ...
Minghui Ou, Futao Zhang, Shichao Cui, Shibo Zhao, Yan Yu   +4 more
doaj   +1 more source

Network meta‐analysis of tocolytics in preterm labor: Establishing an evidence‐based treatment hierarchy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background The choice of tocolytic drugs is one of the most debated aspects of preterm birth management. Objective This network meta‐analysis aimed to establish an evidence‐based hierarchy for tocolytics used in preterm labor by evaluating their efficacy in delaying delivery, safety, and neonatal outcomes.
Barbara Gardella, Chiara Cassani, Vittoria Morteo, Alessandra Marmiroli, Mattia Dominoni, Arsenio Spinillo   +5 more
wiley   +1 more source

Deterioration of preexisting myoclonus following nifedipine use in parkinsonian syndrome: A case report

eNeurologicalSci
L-type calcium channel antagonists are uncommon causes of myoclonus, and the underlying mechanism remains unclear. Here, we report a case of parkinsonian syndrome with deterioration of preexisting myoclonus after nifedipine use.
Gohei Yamada, Takanari Toyoda, Eiichi Katada, Noriyuki Matsukawa   +3 more
doaj   +1 more source

Impact of Magnesium Sulfate versus Nifedipine on Fetal Umbilical Artery Doppler Parameters in Preterm Labor: A Randomized Clinical Study [PDF]

Al-Azhar International Medical Journal, 2000
Background: Preterm birth, is birth prior to thirty-seven weeks of gestation. Aim: To compare the effects of magnesium sulfate & nifedipine on doppler parameters of the embryonic umbilical artery during preterm labor.
Hossam EL-Kattatny, Sileem Sileem, Aamal Youssef   +2 more
doaj   +1 more source