Results 41 to 50 of about 40,278 (255)

Efficacy and Safety of Nifedipine as a Tocolytic Agent in Preterm Labor

Journal of Pharmacy and Bioallied Sciences
Objectives: To study the success or failure of pregnancy with nifedipine and the side effects of nifedipine. Materials and Methods: A prospective observational cohort study was conducted on 138 pregnant women between 28 and 34 weeks of gestation ...
Neelam Nalini, Anika Kujur, Bijeta Singh, Kshitij Aviraj Singh   +3 more
doaj   +1 more source

Nifedipine-Induced Changes in the Electrohysterogram of Preterm Contractions: Feasibility in Clinical Practice

Obstetrics and Gynecology International, 2010
Objective. Evaluating changes in the power spectral density (PSD) peak frequency of the electrohysterogram (EHG) caused by nifedipine in women with preterm contractions. Methods.
Maartje P. G. C. Vinken, C. Rabotti, M. Mischi, J. O. E. H. van Laar, S. G. Oei   +4 more
doaj   +1 more source

Nifedipine: Differential pulse polarography and photodecomposition [PDF]

, 1989
A method for the differential-pulse polarographic determination of nifedipine has been developed, based on the electrochemistry of the aromatic nitro group in the drug.
Squella Serrano, Juan, Núñez Vergara, Luis, L.J. Nuñez-Vergara, J.A. Squella, S. Perna, E. Barnafi, Barnafi, E., Perna, S.   +7 more
core   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Nifedipine Alone or Combined with Sildenafil Citrate for Management of Threatened Preterm Labour [PDF]

Al-Azhar International Medical Journal
Background: Preterm labor (PTL) is defined as the delivery of a baby after twenty weeks of gestation and prior to the completion of thirty-seven weeks of gestation.Aim: To determine whether the tocolytic effect of nifedipine in combination with ...
doaj   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

British Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić, Marta Kučan Štiglić, Ana Jelaković, Bojan Jelaković, Dinko Vitezić   +4 more
wiley   +1 more source

Nifedipine and indomethacin in preventing preterm labor under 32 gestational weeks

Gülhane Tıp Dergisi, 2022
Aims:This study compared nifedipine and indomethacin treatments, commonly used tocolytic agents, in terms of efficacy and maternal side effects.Methods:This retrospective study included pregnant women spontaneous preterm labor between 24 and 32 weeks of ...
Gülşah Dağdeviren, Münevver Aksoy, Özge Yücel Çelik, Ayşe Keleş, Şevki Çelen, Ali Turhan Çağlar   +5 more
doaj   +1 more source

Metabolic Stress Shifts the Function of KCa3.1 Channels in Pancreatic Beta Cells From a Regulator of Membrane Potential to a Proapoptotic Factor [PDF]

Arch Pharm (Weinheim)
KATP and KCa3.1 channels are the main components of the regulatory K+ current “Kslow” of pancreatic beta cells. In a diabetogenic environment, the KCa3.1 component of Kslow decreases, and the channel is dysregulated. A targeted pharmacological approach reveals that KCa3.1 channels are functional in mitochondria.
Hense J, Beuke L, Kick C, Wünsch B, Düfer M.   +4 more
europepmc   +2 more sources

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source