Results 61 to 70 of about 40,278 (255)
Zagazig Journal of Pharmaceutical Sciences, 1993 The effects of a single dose of nifedipine (5 mg/Kg, 1.P.) alone, Cimetidine (25 mg/Kg, I.P. for 7 days) alone or their combination on the arterial blood presure, heart rate, the calculated double product, and electrocardiogram (ECG) in anaesthetized ...
Hassan El-Fayoumi +2 more
doaj +1 more source
Counteraction of nifedipine-induced hyperglycaemia by metformin
, 1990 Nifedipine-induced hyperglycaemia in rats was counteracted by concurrent administration of metformin (500 mg/kg p.o.). However, glibenclamide (5 mg/kg p.o.) did not change the hyperglycaemic effect of nifedipine.
Abu-Jayyab AR, el-Denshary ES
core +1 more source
International Journal of Reproductive BioMedicine, 2019 Background Preterm labor (PTL) is a serious emergency wherein robust management is imperative for achieving improved outcome. Objective To evaluate the efficacy and safety of nifedipine alone vs nifedipine with vaginal ...
Bushra Ashraf
doaj +1 more source
Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and improves muscle function in dystrophic mdx mice. [PDF]
PLoS ONE, 2013 Duchenne Muscular Dystrophy (DMD) is a recessive X-linked genetic disease, caused by mutations in the gene encoding dystrophin. DMD is characterized in humans and in mdx mice by a severe and progressive destruction of muscle fibers, inflammation ...
Francisco Altamirano +6 more
doaj +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract For six decades, pregnant women have been routinely excluded from pharmaceutical clinical trials, a practice rooted in a protectionist ethic that emerged after the thalidomide tragedy. This narrative review examines whether that exclusion remains ethically justifiable, drawing on the obstetric, pharmacological, and bioethical literature ...
Camila Kruger Cabar +1 more
wiley +1 more source
Frontiers in Endocrinology, 2019 Aging is associated with the development of various chronic diseases, in which both cardiovascular disorders and osteoarthritis are dominant. Currently, there is no effective treatment for osteoarthritis, whereas hypertension is often treated with L-type
Ilona Uzieliene +11 more
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Nifedipine: 30 years of clinical experience [PDF]
, 2005 The article contains information on main pharmacological properties of nifedipine, its indications, specific features of various medicinal forms. The present experience of long-term nifedipine treatment is analyzed, according to its influence on clinical
S. Yu. Martsevich
core
Phytotherapy Research, EarlyView.Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng +6 more
wiley +1 more source
Drug Delivery, 2018 Nifedipine is completely absorbed by the gastrointestinal tract and its pharmacokinetics and metabolism may be influenced by microorganisms. If gut microbes are involved in the metabolism of nifedipine, plateau hypoxia may regulate the bioavailability ...
Juanhong Zhang +5 more
doaj +1 more source
Рациональная фармакотерапия в кардиологии, 2015 Aim. To compare information value of antihypertensive effect equability parameters for two drug formulations of nifedipine: long-acting one (nifedipine-XL) and short-acting one (nifedipine-sa).Material and methods. 147 patients with arterial hypertension
V. M. Gorbunov +2 more
doaj +1 more source