Results 61 to 70 of about 55,899 (242)
Safety of nifedipine GITS in stable angina: The ACTION trial [PDF]
, 2006 Aim: We describe the safety profile of nifedipine GITS as assessed from adverse events reported in the ACTION trial in which 7,665 patients with stable, symptomatic coronary artery disease were randomly assigned nifedipine GITS or placebo and followed ...
Brouwer, S. (Sophie) de +5 more
core +3 more sources
Therapeutic role of nifedipine in threatened preterm labor: Current evidence and future perspectives
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Preterm birth occurs in approximately 10% of all pregnancies, and is not only the leading cause of neonatal mortality but also a major contributor to short‐ and long‐term morbidities due to immaturity. Preterm birth has also been linked to an increased risk of maternal cardiovascular and cerebrovascular diseases, making it a critical concern ...
Hikaru Imatake +4 more
wiley +1 more source
Nifedipine promotes the proliferation and migration of breast cancer cells.
PLoS ONE, 2014 Nifedipine is widely used as a calcium channel blocker (CCB) to treat angina and hypertension,but it is controversial with respect the risk of stimulation of cancers. In this study, we demonstrated that nifedipine promoted the proliferation and migration
Dong-Qing Guo +3 more
doaj +1 more source
Рациональная фармакотерапия в кардиологии, 2015 Aim. To compare information value of antihypertensive effect equability parameters for two drug formulations of nifedipine: long-acting one (nifedipine-XL) and short-acting one (nifedipine-sa).Material and methods. 147 patients with arterial hypertension
V. M. Gorbunov +2 more
doaj +1 more source
The prion protein constitutively controls neuronal store-operated ca2+ entry through Fyn Kinase [PDF]
, 2015 The prion protein (PrPC) is a cell surface glycoprotein mainly expressed in neurons, whose misfolded isoforms generate the prion responsible for incurable neurodegenerative disorders.
Agnese eDe Mario +8 more
core +4 more sources
Vascular Calcification: Mechanisms, Models, and Therapies
iNew Medicine, EarlyView.ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
Journal of Nepal Medical Association, 2017 Introduction: Anal fissure is an ischemic ulcer caused by combination of spasm of internal anal sphincter and poor blood supply to the posterior midline of anal canal.
Suman Kumar Shrestha +3 more
doaj +1 more source
Contribution of baicalin on the plasma protein binding displacement and CYP3A activity inhibition to the pharmacokinetic changes of nifedipine in rats in vivo and in vitro. [PDF]
PLoS ONE, 2014 Baicalin purified from the root of Radix scutellariae is widely used in clinical practices. This study aimed to evaluate the effect of baicalin on the pharmacokinetics of nifedipine, a CYP3A probe substrate, in rats in vivo and in vitro. In a randomised,
Zhen-Yu Cheng +5 more
doaj +1 more source
Physical properties and solubility studies of Nifedipine-PEG 1450/HPMCAS-HF solid dispersions [PDF]
, 2018 Low-order high-energy nifedipine (NIF) solid dispersions (SDs) were generated by melt solvent amorphization with polyethylene glycol (PEG) 1450 and hypromellose acetate succinate (HPMCAS-HF) to increase NIF solubility while achieving acceptable physical ...
Chougule, Mahavir B. +6 more
core +1 more source
Drug treatment of hypertension: focus on vascular health [PDF]
, 2016 Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C. +2 more
core +1 more source