Results 71 to 80 of about 56,309 (261)

Therapeutic role of nifedipine in threatened preterm labor: Current evidence and future perspectives

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Preterm birth occurs in approximately 10% of all pregnancies, and is not only the leading cause of neonatal mortality but also a major contributor to short‐ and long‐term morbidities due to immaturity. Preterm birth has also been linked to an increased risk of maternal cardiovascular and cerebrovascular diseases, making it a critical concern ...
Hikaru Imatake   +4 more
wiley   +1 more source

Effectiveness of 0.2% Glyceryl trinitrate and 0.5% Nifedipine in the Treatment of Chronic Anal Fissure

open access: yesJournal of Nepal Medical Association, 2017
Introduction: Anal fissure is an ischemic ulcer caused by combination of spasm of internal anal sphincter and poor blood supply to the posterior midline of anal canal.
Suman Kumar Shrestha   +3 more
doaj   +1 more source

Safety of nifedipine GITS in stable angina: The ACTION trial [PDF]

open access: yes, 2006
Aim: We describe the safety profile of nifedipine GITS as assessed from adverse events reported in the ACTION trial in which 7,665 patients with stable, symptomatic coronary artery disease were randomly assigned nifedipine GITS or placebo and followed ...
Brouwer, S. (Sophie) de   +5 more
core   +3 more sources

Vascular Calcification: Mechanisms, Models, and Therapies

open access: yesiNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu   +5 more
wiley   +1 more source

Plateau hypoxia attenuates the metabolic activity of intestinal flora to enhance the bioavailability of nifedipine

open access: yesDrug Delivery, 2018
Nifedipine is completely absorbed by the gastrointestinal tract and its pharmacokinetics and metabolism may be influenced by microorganisms. If gut microbes are involved in the metabolism of nifedipine, plateau hypoxia may regulate the bioavailability ...
Juanhong Zhang   +5 more
doaj   +1 more source

eNOS-dependent antisenscence effect of a calcium channel blocker in human endothelial cells. [PDF]

open access: yesPLoS ONE, 2014
Senescence of vascular endothelial cells is an important contributor to the pathogenesis of age-associated vascular disorders such as atherosclerosis. We investigated the effects of antihypertensive agents on high glucose-induced cellular senescence in ...
Toshio Hayashi   +6 more
doaj   +1 more source

Kidney function in the very elderly with hypertension: data from the hypertension in the very elderly (HYVET) trial.

open access: yes, 2013
BACKGROUND: numerous reports have linked impaired kidney function to a higher risk of cardiovascular events and mortality. There are relatively few data relating to kidney function in the very elderly. METHODS: the Hypertension in the Very Elderly Trial (
Beckett, Nigel   +10 more
core   +1 more source

Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system. [PDF]

open access: yes, 2017
Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery.
Gimzewski, James K   +7 more
core   +2 more sources

Prenatal exposure to antihypertensive medication: A systematic review of neurodevelopmental and educational outcomes

open access: yesJCPP Advances, EarlyView.
This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf   +5 more
wiley   +1 more source

TREATMENT OF GINGIVAL HYPERPLASIA INDUCED BY NIFEDIPINE

open access: yesJournal of Dentistry Indonesia, 2015
The use of Nifedipine as cardiovascular therapy is proven to be the cause of gingival hyperplasia. The objective of this present case is to report the gingival hyperplasia induced by nifedipine, and the best management suggested.
Mitayani Restuning Kusumarini   +1 more
doaj   +1 more source

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