Results 51 to 60 of about 40,278 (255)

SUSTAINED-RELEASE FORMULATIONS FOR NIFEDIPINE

Zagazig Journal of Pharmaceutical Sciences, 1993
Three formulae of nifedipine sustained release granules were tried, each containing 10% of the drug. The former one was composed of nifedipine, lactose and PVP 40000, and prepared adopting moist granulation technique. In the second formula, the drug, PEG
Mohamed Fetouh
doaj   +1 more source

Nifedipine in Scleroderma Ulcerations [PDF]

, 1984
Cutaneous ulcerations may be due to a variety of causes, including vasculitis. infections, arterial insufficiency, and microvascular damage. The net effect is diminished blood flow to the skin.
John J. Voorhees, Callen, Jeffrey P., Jeffrey P. Callen, Wong, Reynold C., Thomas Y. Woo, Voorhees, John J., Woo, Thomas Y., Campbell, Janis P., Reynold C. Wong, Goldearb, Michael T., Janis P. Campbell, Michael T. Goldearb   +11 more
core   +1 more source

Unbound Intrinsic Formation Clearance of 6β‐Hydroxycortisol Is a Useful Biomarker of CYP3A4 Activity during Pregnancy

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnancy results in multiple physiological changes that impact drug disposition. For example, hepatic CYP3A activity and renal transporter‐mediated clearance increase in late pregnancy, but the time course of these changes across pregnancy is not known.
Aurora K Authement, Mary F Hebert, Emily E Fay, Nina Isoherranen   +3 more
wiley   +1 more source

Deterioration of preexisting myoclonus following nifedipine use in parkinsonian syndrome: A case report

eNeurologicalSci
L-type calcium channel antagonists are uncommon causes of myoclonus, and the underlying mechanism remains unclear. Here, we report a case of parkinsonian syndrome with deterioration of preexisting myoclonus after nifedipine use.
Gohei Yamada, Takanari Toyoda, Eiichi Katada, Noriyuki Matsukawa   +3 more
doaj   +1 more source

Impact of Magnesium Sulfate versus Nifedipine on Fetal Umbilical Artery Doppler Parameters in Preterm Labor: A Randomized Clinical Study [PDF]

Al-Azhar International Medical Journal, 2000
Background: Preterm birth, is birth prior to thirty-seven weeks of gestation. Aim: To compare the effects of magnesium sulfate & nifedipine on doppler parameters of the embryonic umbilical artery during preterm labor.
Hossam EL-Kattatny, Sileem Sileem, Aamal Youssef   +2 more
doaj   +1 more source

Nifedipine interactions in hypertensive patients

, 1990
Nifedipine interactions in hypertensive patients have been evaluated, taking into account both the possibility that the inhibition of prostaglandin (PG) synthesis induced by non-steroidal antiinflammatory drugs (NSAIDs) can reduce the antihypertensive ...
Salvetti A, Abdel Haq B, Giovannetti R., MAGAGNA, ARMANDO, Lenzi M   +4 more
core   +1 more source

Dual effect of nifedipine on pregnant human myometrium contractility: Implication of TRPC1

, 2022
Nifedipine, an L‐type voltage‐gated Ca(2+) channel (L‐VGCC) blocker, is one of the most used tocolytics to treat preterm labor. In clinical practice, nifedipine efficiently decreases uterine contractions, but its efficacy is limited over time, and ...
Konig, Stéphane, Yart, Lucile Adeline, Begoña Martinez de Tejada, Lucile Yart, Yart, Lucile, Frieden, Maud, Martinez de Tejada, Begoña, Martinez De Tejada Weber, Begona, Stéphane Konig, Cohen, Marie-Benoîte, Maud Frieden, Cohen, Marie, Marie Cohen   +12 more
core   +1 more source

Cost‐effectiveness of a randomized controlled trial comparing low‐dose aspirin to placebo for the prevention of recurrent preterm birth

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 399-407, April 2025.
Abstract To assess the cost‐effectiveness of low‐dose aspirin compared to placebo for the prevention of recurrent preterm birth from a healthcare perspective. This was a cost‐effectiveness analysis alongside a multicenter, randomized, double‐blinded, placebo‐controlled trial.
Anadeijda J. E. M. C. Landman, Hana M. Broulikova, Laura Visser, Tobias A. J. Nijman, Marieke A. C. Hemels, Karin C. Vollebregt, Elisabeth M. A. Boormans, Henk A. Bremer, Esther Tuinman, Josje Langenveld, Flip van der Made, Robbert J. P. Rijnders, Huib A. A. M. van Vliet, Liv M. Freeman, Roel de Heus, Judith Blaauw, Ineke Krabbendam, Rafli van de Laar, Marieke F. G. Verberg, Hubertina C. J. Scheepers, Ben W. Mol, Christianne J. M. de Groot, Martijn A. Oudijk, Judith E. Bosmans, Marjon A. de Boer   +24 more
wiley   +1 more source

Oral nifedipine may be a preferential option for treating acute severe hypertension during pregnancy: a meta-analysis

Hypertension in Pregnancy, 2023
Aim To compare oral nifedipine and intravenous labetalol in the treatment of acute severe hypertension in pregnancy (SHP). Methods The primary outcomes were the required time to achieve target blood pressure (RTATBP), systolic blood pressure (SBP) and ...
Minghui Ou, Futao Zhang, Shichao Cui, Shibo Zhao, Yan Yu   +4 more
doaj   +1 more source

Network meta‐analysis of tocolytics in preterm labor: Establishing an evidence‐based treatment hierarchy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background The choice of tocolytic drugs is one of the most debated aspects of preterm birth management. Objective This network meta‐analysis aimed to establish an evidence‐based hierarchy for tocolytics used in preterm labor by evaluating their efficacy in delaying delivery, safety, and neonatal outcomes.
Barbara Gardella, Chiara Cassani, Vittoria Morteo, Alessandra Marmiroli, Mattia Dominoni, Arsenio Spinillo   +5 more
wiley   +1 more source