Results 81 to 90 of about 56,309 (261)

Contribution of baicalin on the plasma protein binding displacement and CYP3A activity inhibition to the pharmacokinetic changes of nifedipine in rats in vivo and in vitro. [PDF]

open access: yesPLoS ONE, 2014
Baicalin purified from the root of Radix scutellariae is widely used in clinical practices. This study aimed to evaluate the effect of baicalin on the pharmacokinetics of nifedipine, a CYP3A probe substrate, in rats in vivo and in vitro. In a randomised,
Zhen-Yu Cheng   +5 more
doaj   +1 more source

Gene Expression in Experimental Aortic Coarctation and Repair: Candidate Genes for Therapeutic Intervention? [PDF]

open access: yes, 2015
Coarctation of the aorta (CoA) is a constriction of the proximal descending thoracic aorta and is one of the most common congenital cardiovascular defects.
Bozdag, Serdar   +5 more
core   +3 more sources

Revisiting the Association Between Calcium Channel Blockers and Parkinson's Disease in the E3N Cohort

open access: yesMovement Disorders, EarlyView.
Abstract Background Previous studies on calcium channel blockers (CCBs) and Parkinson's disease (PD) risk reached conflicting conclusions. Objectives We examined the relationship between CCBs and PD in the E3N cohort of French women followed for 15 years (2004–2018), while taking into account the potential for reverse causation.
Emilie Moutard   +9 more
wiley   +1 more source

Modulation of a sustained calcium current by intracellular pH in horizontal cells of fish retina. [PDF]

open access: yes, 1993
A sustained high voltage-activated (HVA), nifedipine- and cadmium-sensitive calcium current and a sustained calcium action potential (AP) were recorded from horizontal cells isolated from catfish retina.
Copenhagen, DR, Dixon, DB, Takahashi, K
core  

The mechanisms of calcium homeostasis and signalling in the lens [PDF]

open access: yes, 2008
Excessive Ca2+ can be detrimental to cells and raised levels of Ca2+ in human lenses with cortical cataract have been found to play a major role in the opacification process.
Rhodes, JD, Sanderson, J
core   +1 more source

Interventions and Perinatal Outcomes Associated With Recipient Twin Cardiomyopathy in the Setting of Twin‐To‐Twin Transfusion Syndrome: A Systematic Review

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To determine (1) Whether the presence and severity of recipient twin cardiomyopathy in the setting of twin‐to‐twin transfusion syndrome are associated with worse perinatal outcomes when compared to recipient twins without evidence of cardiomyopathy and (2) The optimal management strategy to reduce the likelihood of adverse perinatal ...
Briana Tolbert   +7 more
wiley   +1 more source

Prenatal and Perinatal Outcomes in Fetuses With Macrocystic Congenital Pulmonary Airway Malformations: Thoracoamniotic Shunting Versus Expectant Management

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective Describe prenatal imaging characteristics, perinatal and postnatal outcomes in fetuses with isolated macrocystic congenital pulmonary airway malformations (CPAM) undergoing thoracoamniotic shunting (TAS) and expectant management. Methods Retrospective cohort study of 123 fetuses with isolated macrocystic CPAM managed at the Ontario ...
Laurence Sophie Carmant   +9 more
wiley   +1 more source

Medication prescription patterns in cancer rehabilitation physiatry outpatients: A multicenter retrospective study

open access: yesPM&R, EarlyView.
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen   +7 more
wiley   +1 more source

The Upregulation of α2δ-1 Subunit Modulates Activity-Dependent Ca2+ Signals in Sensory Neurons. [PDF]

open access: yes, 2015
As auxiliary subunits of voltage-gated Ca(2+) channels, the α2δ proteins modulate membrane trafficking of the channels and their localization to specific presynaptic sites.
Cassidy, JS   +3 more
core   +1 more source

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria

open access: yesAllergy, EarlyView.
ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
T. Zuberbier   +221 more
wiley   +1 more source

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