Results 81 to 90 of about 55,899 (242)
Allergy, EarlyView.ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
T. Zuberbier +221 more
wiley +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source
Slowly cycling Rho kinase-dependent actomyosin cross-bridge slippage explains intrinsic high compliance of detrusor smooth muscle [PDF]
, 2017 Biological soft tissues are viscoelastic because they display timeindependent pseudoelasticity and time-dependent viscosity. However, there is evidence that the bladder may also display plasticity, defined as an increase in strain that is unrecoverable ...
Hurley, Tanner +6 more
core +2 more sources
A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals
British Journal of Pharmacology, EarlyView.Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig +7 more
wiley +1 more source
The mechanisms of calcium homeostasis and signalling in the lens [PDF]
, 2008 Excessive Ca2+ can be detrimental to cells and raised levels of Ca2+ in human lenses with cortical cataract have been found to play a major role in the opacification process.
Rhodes, JD, Sanderson, J
core +1 more source
Lactate Accelerates Early Angiogenesis and Bone Regeneration Through Macrophage M1 Polarisation
Cell Proliferation, EarlyView.During the early stage of bone defect healing, lactate accumulates and contributes to increasing NOD1 expression by stabilising HIF1α that in turn triggers a calcium influx, which ultimately polarises macrophages towards the M1 phenotype and accelerates vascularisation of endothelial cells.
Lulu Liu +10 more
wiley +1 more source
PharmaceuticalsInsulin resistance, induced by high fructose consumption, affects cognitive function negatively. Nifedipine may be suggested for neurological disorders.
Nancy M. Abdel-Kareem +6 more
doaj +1 more source
Diabetic Medicine, EarlyView.Abstract Introduction Type 2 diabetes is a complex condition with a multifactorial pathogenesis. The pathogenesis is considered to be polygenic due to complex interactions between genetic/epigenetic and environmental factors. The aim of this study is to determine the genetic, environmental and lifestyle factors associated with the development of type 2
Sunny Chinenye +18 more
wiley +1 more source
Cellular Physiology and Biochemistry, 2016 Background/Aims: By inducing severe endothelial impairment, hypertension and diabetes are two leading causes of morbidity and mortality. Hypertensive patients with concomitant diabetes must take both antihypertensive and hypoglycaemic medications, for ...
Li-Ping Wang +6 more
doaj +1 more source
EVALUATION OF THE EFFECTS OF THREE NOVEL CALCIUM CHANNEL BLOCKERS ON BLOOD PRESSURE, CARDIAC CONTRACTILITY AND HEART RATE IN RABBIT [PDF]
Calcium channel blockers are an important group of drugs that have been used in the treatment of cardiovascular disorders, especially hypertensive states.
اسمعيلي, فرزانه +4 more
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