Results 211 to 220 of about 2,430,619 (291)

Incorporation of the National Institute of Health (NIH) sex as a biological variable policy by R01 grant awardees. [PDF]

Commun Med (Lond)
Warden JH, Parangalan M, Welty LJ, Woitowich NC.   +3 more
europepmc   +1 more source

MXene Wrapped Magnetic Mesocrystals for Durable Redox Catalytic Cancer Therapy and Responsive MRI

Advanced Functional Materials, EarlyView.
Conformal wrapping of ultrathin Ti3C2Tx MXene nanosheets on Fe3O4 mesocrystals creates topology‐stabilized Schottky junctions that direct photoinduced electron transfer under NIR irradiation. The unique architecture sustains Fenton catalysis, promotes continuous hydroxyl radical production, and provides photo‐responsive MRI contrast.
Min Jun Ko, Seongchan Kim, Jun‐Hyeok Han, Sanghee Lee, Minji Ahn, Hong En Fu, Young Jun Jang, Yoo Sang Jeon, Weiguo Li, Young Keun Kim, Dong‐Hyun Kim   +10 more
wiley   +1 more source

Correction to: STING agonists drive recruitment and intrinsic type I interferon responses in monocytic lineage cells for optimal anti-tumor immunity. [PDF]

J Immunol
europepmc   +1 more source

Perivascular space, brain functional connectivity and sleep: a healthy aging population study. [PDF]

NPJ Biol Timing Sleep
Shih NC, Contreras JA, Mack WJ, Choupan J.   +3 more
europepmc   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

Antisense Oligonucleotides Directed Against a Human Endogenous Retrovirus for Treatment of Amyotrophic Lateral Sclerosis

Neurotherapeutics
Kevon Sampson, M.S., Wenxue Li, Ph.D., Myoung Hwa Lee, Ph.D., Lisa Henderson, Ph.D., Avindra Nath, M.D.   +4 more
doaj   +1 more source

Dynamic monitoring of antibody drug conjugates targeting TROP2 or HER2 in breast cancer using circulating tumor cells. [PDF]

Proc Natl Acad Sci U S A
Mishra A, Abelman RO, Cunneely Q, Putaturo V, Deshpande AA, Bell R, Seider EM, Xu KH, Shan M, Kelly J, Huang SB, Rieur O, Knape J, Gopinathan KA, Kikkeri K, Edd JF, Walsh J, Dai CS, Ellisen LW, Ting DT, Nieman L, Toner M, Bardia A, Haber DA, Maheswaran S.   +24 more
europepmc   +1 more source

Shape Memory Microneedle to Prevent Risks of Reproductive Hormone Therapy by Switching Sustained to Burst Release Under a Single Transdermal Insertion

Advanced Functional Materials, EarlyView.
A shape‐memory microneedle system enables reproductive hormone therapy through a single transdermal insertion. The X‐shaped device sustains follicle‐stimulating hormone release for three days, and mild heating restores the O shape to trigger burst human chorionic gonadotropin release.
Sungwoo Cho, Hyunjae Kim, Seung Eun Yu, Sangmin Lee, Ji Youn Lee, Mi‐Lan Kang, Kang Suk Lee, Young Sik Choi, Hak‐Joon Sung   +8 more
wiley   +1 more source

Surgical Advance Care Planning: Initial Validation of Patient Portal Messages for a Multisite Randomized Controlled Trial. [PDF]

Jt Comm J Qual Patient Saf
Welton L, Sudore RL, Botsford C, O'Brien S, Carmichael JC, Melton GB, Wick E.   +6 more
europepmc   +1 more source