Results 221 to 230 of about 2,430,619 (291)

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

HARMONIZATION MITIGATES DIFFUSION MRI SCANNER EFFECTS IN INFANCY: INSIGHTS FROM THE HEALTHY BRAIN AND CHILD DEVELOPMENT (HBCD) STUDY. [PDF]

Proc IEEE Int Symp Biomed Imaging
McMaster EM, Rudravaram G, Kim ME, Schwartz TM, Scholten C, Yoon J, Saunders AM, Hucke ATS, Ramadass K, Harriott EM, Meisler SL, Vandekar SN, Newton A, Smith SA, Sengupta S, Humphreys KL, Osmundson S, Moyer D, Cutting LE, Landman BA.   +19 more
europepmc   +1 more source

A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair

Advanced Healthcare Materials, EarlyView.
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret, Ryan M. Friedman, Gautham Nair, Stephanie L. Fung, Dana D. Ragbirsingh, John Germiller, Riccardo Gottardi   +6 more
wiley   +1 more source

COPD stage progression and regression: a multistate transition analysis of the COPDGene cohort. [PDF]

Am J Respir Crit Care Med
Sánchez-Romero LM, Brouwer AF, Meza R, Levy DT, Torres-Alvarez R, Han MK.   +5 more
europepmc   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Assessing the Utility, Content Validity, and Reliability of the Adverse Event Unit for Gene Therapy Clinical Trials

Neurotherapeutics
Radha Patel, B.A., Michael Hehir, M.D., Meghan McAnally, M.D., Mark Conaway, Abigail Potticary, B.A.Sc., Carsten Bönnemann, M.D., Matthew J. Gooden, M.S., Sandra B. Martin, M.S., Lauren Reoma, M.D.   +8 more
doaj   +1 more source

Transcutaneous auricular vagus nerve stimulation for moderate to severe chronic prostatitis/chronic pelvic pain syndrome (TASC-P) in China: study protocol for a randomised controlled trial. [PDF]

BMJ Open
Wei X, Cui J, Zang Z, Pang R, Qi L, Wang Y, Wang HB, Wu Y, Qin Z, Wu J.   +9 more
europepmc   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Trends in discharge to hospice after critical illness among US Medicare beneficiaries, 2011-2023. [PDF]

Ann Am Thorac Soc
Law AC, Bosch NA, Song Y, Tale AP, Nelson J, Wadhera RK, Barnato AE, Walkey AJ.   +7 more
europepmc   +1 more source