Mycobacterium tuberculosis bacillus induces pyroptosis in human lung fibroblasts [PDF]
We previously reported that live, but not dead, virulent Mycobacterium tuberculosis (Mtb) H37Rv bacilli induce cell death in human lung fibroblast cell lines, MRC-5, MRC-9, and TIG-1.
Asami, Yukihiro +11 more
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Role of MIR-29B-1 and MIR-29A in endocrine-resistant breast cancer. [PDF]
, 2017 Therapies targeting estrogen receptor α (ERα) including selective estrogen receptor modulators (SERMs), e.g., tamoxifen (TAM); selective estrogen receptor downregulators (SERDs), e.g., fulvestrant (ICI 182,780); and aromatase inhibitors (AI), e.g ...
Muluhngwi, Penn
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Gene Expression and Discovery During Lens Regeneration in Mouse: Regulation of Epithelial to Mesenchymal Transition and Lens Differentiation [PDF]
, 2006 Purpose: It has been shown that after extracapsular lens removal by anterior capsulotomy in the mouse, the lens can be regenerated. However, as the capsular bag is filled with fibers, epithelial to mesenchymal transition (EMT), an event which is common ...
Call, Mindy Kay +4 more
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Determining the impact of the R249S mutation on Tp53 gene on cell survivability during AFB1 exposure [PDF]
, 2022 Hepatocellular Carcinoma (HCC) is one of the most frequent and malignant cancers worldwide and is found to be endemic in the same geographically areas as high exposure with Aflatoxin B1 (AFB1).
Fonnes, Helene
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Molecular mechanisms of cell death:recommendations of the Nomenclature Committee on Cell Death 2018 [PDF]
, 2018 Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives.
Aaronson, Stuart A. +168 more
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Type 2 Bovine Viral Diarrhea Virus N\u3csup\u3epro\u3c/sup\u3e Suppresses Type I Interferon Pathway Signaling in Bovine Cells and Augments Bovine Respiratory Syncytial Virus Replication [PDF]
, 2018 Bovine viral diarrhea virus (BVDV) and bovine respiratory syncytial virus (BRSV) infections contribute to the bovine respiratory disease complex (BRDC), which is a multi-factorial disorder involving co-infections of viruses and bacteria including ...
Alkheraif, Abdulrahman Abdulaziz A.
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Knowledge Discovery in Databases of Proteomics by Systems Modeling in Translational Research on Pancreatic Cancer [PDF]
BACKGROUND: Knowledge discovery in databases (KDD) can contribute to translational research, also known as translational medicine, by bridging the gap between METHODS: This framework includes the data collection of a composition model (various research ...
Aarvik, Anne +16 more
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The molecular mechanisms of peptidyl-prolyl cis/trans isomerase Pin1 and its relevance to kidney disease [PDF]
Pin1 is a member of the peptidyl-prolyl cis/trans isomerase subfamily and is widely expressed in various cell types and tissues. Alterations in Pin1 expression levels play pivotal roles in both physiological processes and multiple pathological conditions,
Fang Wang +10 more
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Roscovitine Inhibits Endotoxin-Induced Lung Inflammation in Mice Lacking Peptidylprolyl Cis/Trans Isomerase, NIMA-Interacting 1 (PIN1) [PDF]
Pulmonary and Critical Care Medicine, 2016 Benjamin W Newell +3 more
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Investigation of Novel Functions for DNA Damage Response and Repair Proteins in Escherichia coli and Humans [PDF]
, 2016 Endogenous and exogenous agents that can damage DNA are a constant threat to genome stability in all living cells. In response, cells have evolved an array of mechanisms to repair DNA damage or to eliminate the cells damaged beyond repair.
Hilton, Benjamin A
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