Results 41 to 50 of about 3,881 (179)

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

open access: yesAdvanced Science, Volume 13, Issue 43, 3 August 2026.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander   +14 more
wiley   +1 more source

ENHANCEMENT OF ANTIBACTERIAL ACTIVITY OF TETRACYCLINE HYDROCHLORIDE BY NIOSOMAL ENCAPSULATION

open access: yesZagazig Journal of Pharmaceutical Sciences, 2005
Topical use of antibiotics is currently a widely accepted effective and safe treatment for topical infections. One potential strategy for improving topical administration of drugs is to encapsulate the drug in a colloidal carrier.
Omaima Sammour   +3 more
doaj   +1 more source

Advancing gambogic acid for translational oncology: Redox–proteostasis collapse, multidrug resistance reversal, nanodelivery and biomarker‐guided development

open access: yesClinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Gambogic acid exerts anticancer effects through reactive oxygen species‐mediated apoptosis, suppression of nuclear factor kappa B and phosphatidylinositol‐3‐kinase–protein kinase B signalling, multidrug resistance modulation and tumour microenvironment effects.
Uttam Singh Baghel   +14 more
wiley   +1 more source

Assessment of Different Niosome Formulations for Optogenetic Applications: Morphological and Electrophysiological Effects

open access: yesPharmaceutics, 2023
Gene therapy and optogenetics are becoming promising tools for treating several nervous system pathologies. Currently, most of these approaches use viral vectors to transport the genetic material inside the cells, but viruses present some potential risks,
José David Celdrán   +11 more
doaj   +1 more source

Folic Acid-Decorated pH-Responsive Nanoniosomes With Enhanced Endocytosis for Breast Cancer Therapy: In Vitro Studies

open access: yesFrontiers in Pharmacology, 2022
Breast cancer is the most common invasive cancer in women and the second leading cause of cancer death in women after lung cancer. The purpose of this study is a targeted delivery toward in vitro (on MCF7 and 4T1 breast cancer cell lines) through ...
Tahereh Rezaei   +14 more
doaj   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 27, 17 July 2026.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha   +9 more
wiley   +1 more source

Application of Box-Behnken Design in the Preparation, Optimization, and In-Vivo Pharmacokinetic Evaluation of Oral Tadalafil-Loaded Niosomal Film

open access: yesPharmaceutics, 2023
Benign prostatic hyperplasia (BPH) affects about 90% of men whose ages are over 65. Tadalafil, a selective PDE-5 inhibitor, was approved by FDA for BPH, however, its poor aqueous solubility and bioavailability are considered major drawbacks.
Kawthar K. Abla   +3 more
doaj   +1 more source

Apple Pomace Pectin for Gastroprotective Nutraceutical Delivery: Structure–Function Relationships and Nano/Microencapsulation Strategies for Gastric Ulcer Management

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
Apple pomace pectin is explored as a sustainable and multifunctional biomaterial for gastric ulcer management. Its unique structural features confer mucoadhesive, anti‐inflammatory, antioxidant, and anti‐Helicobacter pylori activities while enabling nano/microencapsulation of therapeutic agents.
Akash Dhiman   +6 more
wiley   +1 more source

A COMPREHENSIVE REVIEW ON NIOSOMES

open access: yesJournal of Biomedical and Pharmaceutical Research, 2020
Niosomes are a bilayered non-toxic, non-immunogenic nanoparticular delivery system; it is being used for drug delivery. Owing to its cost-effectiveness and easy manufacturing processing, niosomes are gaining popularity as a coveted drug carrier. Main constituents of a niosomes are cholesterol and a non-ionic surfactant, although several additives like ...
null Preeti Budhlakoti   +2 more
openaire   +2 more sources

Self‐Assembling Cationic Lipopeptides for the Construction of Functional Vesicular Gene‐Delivery Systems

open access: yesSmall, Volume 22, Issue 42, 27 July 2026.
Cationic lipopeptides self‐assemble into stable, cell‐like vesicles that merge peptide programmability with lipid self‐organization. These biocompatible compartments efficiently sequester and deliver nucleic acids, enabling high transfection efficiency with low‐toxicity in both HEK293T cells and mesenchymal stem cells (MSCs).
Federica A. Souto‐Trinei   +4 more
wiley   +1 more source

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