Results 61 to 70 of about 3,881 (179)

Innovative Drug Delivery Systems for the Treatment of Glaucoma

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu, Junzhi Li, Zhenlin Chen, Jinyu Zhang, Siqi Feng, Jiaying Huang, Yawen Chu, Xue Zhou, Wei Wang, Shangsi Chen   +9 more
wiley   +1 more source

Machine Learning‐Driven Predictive Modeling and Multi‐Objective Exploration of Oxaliplatin‐Loaded Nanocarriers for Enhanced Loading and Encapsulation Efficiency

Materials Genome Engineering Advances, Volume 4, Issue 2, June 2026.
Integrating ML and multi‐objective optimization enabled efficient, accurate design of nanocarriers with optimized loading and encapsulation efficiencies. ABSTRACT Oxaliplatin (OXA), a critical third‐generation platinum chemotherapeutic, is significantly limited by suboptimal loading capacity and encapsulation efficiency in nanoparticle‐based delivery ...
Abbas Rahdar, Maryam Shirzad, Sonia Fathi‐Karkan, M. Ali Aboudzadeh   +3 more
wiley   +1 more source

Smart Polymer‐Based Drug Delivery Systems for Managing Infective Conjunctivitis: Advances and Future Prospects

Nano Select, Volume 7, Issue 6, June 2026.
The introduction covers the background and significance of conjunctivitis. It continues with a review of etiology, epidemiology, and clinical manifestations. Diagnostic methods are described, followed by discussions on pathophysiology and classification. Current treatment strategies, preventive measures, and therapeutic challenges are analyzed.
Xia Linkang, Marwan Abdelmahmoud Abdelkarim Maki, Saad Tayyab, Sachin Thakur, Pankaj Kumar, Ritu Karwasra, Mahesh Harihar Behare, Nitin Sharma, Wan Hamirul Bahrin Wan Kamal, Oganeswary Kobi, Kushagra Khanna, Mogana Rajagopal   +11 more
wiley   +1 more source

Curcumin Nanoformulations for Dermatological Applications: From Nutraceuticals to Nanocarriers

Food Frontiers, Volume 7, Issue 3, May 2026.
Nanotechnology‐based delivery platforms enhance the cutaneous administration of curcumin. Loading free curcumin into polymeric micelles, metal‐based nanoparticles, nanogels/hydrogels, liposomes, polymeric nanoparticles, or nanoemulsions/nanocrystals helps address its low solubility, poor stability and limited skin permeation. As a result, these systems
Stephany Celeste Gutiérrez‐Ruiz, Alejandra Romero‐Montero, Hector Hernández‐Parra, Sheila I. Peña‐Corona, Héctor Adrián García‐Gasca, Katya Carbone, Fabio Gervasi, Shivaprasad Shetty Mangalpady, Rajesh Kaverikana, Mariia Shanaida, Volodymyr Shanaida, Daniela Calina, Javad Sharifi‐Rad, Gerardo Leyva‐Gómez   +13 more
wiley   +1 more source

Sustainable Applications of Thymol: Advances in Formulation Technologies, Drug Delivery Systems, and Food Preservation Strategies

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Thymol is a natural monoterpene with antimicrobial, antioxidant, anti‐inflammatory, and anticancer activities relevant to food and biomedical applications. Its poor solubility and instability can be improved through nanodelivery systems. Thymol also supports sustainable food preservation and active packaging, although further clinical validation and ...
Farhang Hameed Awlqadr, Mohammed N. Saeed, Ammar B. Altemimi, Syamand Ahmed Qadir, Aryan Mahmood Faraj, Othman Abdulrahman Mohammed, Tablo H. Salih, Rawaa H. Tlay, Tarek Gamal Abedelmaksoud   +8 more
wiley   +1 more source

Microfluidic manufacturing of different niosomes nanoparticles for curcumin encapsulation: Physical characteristics, encapsulation efficacy, and drug release

Beilstein Journal of Nanotechnology, 2019
Curcumin, a natural chemical compound found in Curcuma longa that has been used in antitumor and anti-inflammation applications, exhibits very limited water solubility and rapid in vivo degradation, which limits its clinical application.
Mohammad A. Obeid, Ibrahim Khadra, Abdullah Albaloushi, Margaret Mullin, Hanin Alyamani, Valerie A. Ferro   +5 more
doaj   +1 more source

Efficient PEGylated magnetic nanoniosomes for co-delivery of artemisinin and metformin: a new frontier in chemotherapeutic efficacy and cancer therapy

Scientific Reports
Two strategies were employed to modify the performance of the nano-niosome drug delivery system. Initially, the surface of the nano-niosomes underwent modification through the inclusion of polyethylene glycol, thereby altering its properties ...
Rasoul Shahbazi, Zohreh Mirjafary, Nosratollah Zarghami, Hamid Saeidian   +3 more
doaj   +1 more source

In vitro and in vivo investigation for optimization of niosomal ability for sustainment and bioavailability enhancement of diltiazem after nasal administration

Drug Delivery, 2017
Diltiazem hydrochloride (DTZ) is a calcium channel antagonist depicted by extensive first pass metabolism and low oral bioavailability. The aim of this work was to develop niosomes for potential nasal delivery of DTZ.
H. O. Ammar, M. Haider, M. Ibrahim, N. M. El Hoffy   +3 more
doaj   +1 more source

Formulation and Characterization of Drug Loaded Nonionic Surfactant Vesicles (Niosomes) for Oral Bioavailability Enhancement

The Scientific World Journal, 2014
Nonionic surfactant vesicles (niosomes) were formulated with an aim of enhancing the oral bioavailability of tenofovir disoproxil fumarate (TDF), an anti-HIV drug.
Sunil Kamboj, Vipin Saini, Suman Bala
doaj   +1 more source

Development of Vancomycin, a Glycopeptide Antibiotic, in a Suitable Nanoform for Oral Delivery

Molecules
Bacterial infections caused by resistant strains have emerged as one of the most significant life-threatening challenges. Developing alternatives to conventional antibiotic formulations is crucial to overcoming these challenges. Vancomycin HCl (VCM) is a
Ali A. Amer, Lewis Bingle, Cheng Shu Chaw, Amal Ali Elkordy   +3 more
doaj   +1 more source