Results 71 to 80 of about 15,834 (217)

A general framework for modeling pathogen transmission in co‐roosting host communities

Ecology, Volume 107, Issue 2, February 2026.
Abstract Cross‐species transmission of pathogens can be facilitated by frequent contact among wildlife. Cross‐species transmission is often driven by phylogenetic similarity between host species, but the role this plays when multiple host species co‐roost is unknown.
Molly C. Simonis, Daniel J. Becker
wiley   +1 more source

Structural Insights Into the Nuclear Import of Gallid Alphaherpesvirus 1 Large Tegument Protein

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
The study identifies and characterizes a bipartite nuclear localization signal within the GaAHV‐1 UL36 large tegument protein, revealing its structural interaction with importin α/β1 and confirming a conserved mechanism of nuclear import through biochemical, crystallographic, and mutational analyses.
Babu Kanti Nath, Crystall M. D. Swarbrick, Reuben Blades, Daryl Ariawan, Ole Tietz, Gualtiero Alvisi, Jade K. Forwood, Subir Sarker   +7 more
wiley   +1 more source

Accelerate the Highly Efficient Development of mRNA Vaccines Through Advanced Computational Methods

MedComm, Volume 7, Issue 2, February 2026.
This review explores the recent advancements in applying computational methods to optimize mRNA vaccines, with a primary focus on improvements in sequence design and delivery systems. ABSTRACT mRNA medicine is an emerging therapeutic approach that utilizes messenger RNA to synthesize functional proteins directly within target cells.
Ruichu Gu, Duanmiao Si, Dingwei Lei, Xiaoxue Xie, Yongge Li, Han Wen   +5 more
wiley   +1 more source

Inhibition of Henipavirus fusion and infection by heptad-derived peptides of the Nipah virus fusion glycoprotein

Virology Journal, 2005
Background The recent emergence of four new members of the paramyxovirus family has heightened the awareness of and re-energized research on new and emerging diseases.
Eaton Bryan T, Wang Lin-Fa, Crameri Gary, Mungall Bruce A, Bossart Katharine N, Broder Christopher C   +5 more
doaj   +1 more source

Identifying Early Target Cells of Nipah Virus Infection in Syrian Hamsters. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Nipah virus causes respiratory and neurologic disease with case fatality rates up to 100% in individual outbreaks. End stage lesions have been described in the respiratory and nervous systems, vasculature and often lymphoid organs in fatal ...
Laura Baseler, Dana P Scott, Greg Saturday, Eva Horne, Rebecca Rosenke, Tina Thomas, Kimberly Meade-White, Elaine Haddock, Heinz Feldmann, Emmie de Wit   +9 more
doaj   +1 more source

Virus Nipah

JURNAL BIOMEDIK (JBM), 2016
Abstract: Nipah virus caused outbreaks in Malaysia and Singapore in 2009 with a high mortality rates. It also erupted in Bangladesh, India, and the Philippines. Nipah virus infection varies from asymptomatic to severe manifestation with a mortality rate varies from 38% to 80%.
openaire   +3 more sources

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, Volume 26, Issue 2-3, Page 33-80, February 2026.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Tackling a global epidemic threat: Nipah surveillance in Bangladesh, 2006-2021.

PLoS Neglected Tropical Diseases, 2023
Human Nipah virus (NiV) infection is an epidemic-prone disease and since the first recognized outbreak in Bangladesh in 2001, human infections have been detected almost every year.
Syed Moinuddin Satter, Wasik Rahman Aquib, Sharmin Sultana, Ahmad Raihan Sharif, Arifa Nazneen, Muhammad Rashedul Alam, Ayesha Siddika, Fateha Akther Ema, Kamal Ibne Amin Chowdhury, Ahmed Nawsher Alam, Mahmudur Rahman, John D Klena, Mohammed Ziaur Rahman, Sayera Banu, Tahmina Shirin, Joel M Montgomery   +15 more
doaj   +1 more source

Public Health Threat of New, Reemerging, and Neglected Zoonoses in the Industrialized World [PDF]

, 2010
Microbiologic infections acquired from animals, known as zoonoses, pose a risk to public health. An estimated 60% of emerging human pathogens are zoonotic. Of these pathogens, >71% have wildlife origins.
Cutler, S.J., Fooks, A.R., Poel, W.H.M., van der   +2 more
core   +2 more sources

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source