Results 51 to 60 of about 3,504 (232)

Prenatal Evaluation of RNU4‐2 Variants in Fetuses With Central Nervous System Anomalies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Fetal central nervous system (CNS) anomalies are among the most common congenital malformations, yet the overall prenatal diagnostic yield of current genetic testing remains below 40%. Variants in RNU4‐2, a non‐coding gene encoding the U4 small nuclear RNA (snRNA), have recently been linked to a novel highly recurrent dominant ...
Yiyao Chen, Li Gao, Xu Han, Yunyun Cao, Lanlan Zhang, Yi Wu, Xinrong Zhao, Wenjing Hu, Ruiyu Ma, Renyi Hua, Niu Li, Yanlin Wang, Jian Wang, Shuyuan Li   +13 more
wiley   +1 more source

Investigation of intervertebral disc degeneration using multivariate FTIR spectroscopic imaging [PDF]

, 2016
Traditionally tissue samples are analysed using protein or enzyme specific stains on serial sections to build up a picture of the distribution of components contained within them.
Detiger, Suzanne E. L., Helder, Marco N., Le Maitre, Christine, Mader, Kerstin, Peeters, Mirte, Sammon, Chris, Smit, Theo H.   +6 more
core   +2 more sources

Evaluating the Impact of Cellulose Nanocrystals on the Performance of Polycarbonate Thin‐Film Nanocomposite Membranes for Treating Oily Wastewater

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT A new type of thin‐film nanocomposite (TFN) membrane was synthesized by incorporating cellulose nanocrystals (CNCs) into a polyvinyl alcohol (PVA) top layer on a polycarbonate (PC) substrate via dip‐coating. The synthesized TFC and TFN membranes (PC/PVA TFC and PC/PVA‐CNC TFN membranes) were evaluated using contact angle measurement, field ...
Habib Etemadi, Naser Ghasemian, Homayun Khezraqa, Solmaz Tozihi, Seyed Mehdi Sajjadi, Omid Ahmadi   +5 more
wiley   +1 more source

Design of Experiments‐Based Optimization of Recovered Carbon Black–Reinforced Isobutylene–Isoprene Rubber in Comparison With Conventional Carbon Black Systems

Journal of Applied Polymer Science, EarlyView.
Optimized potential of rCB via DOE: recovered carbon black from end‐of‐life tires was assessed as a full substitute for conventional carbon black in IIR composites. DOE and response surface methodology optimized rCB loading, plasticizer, and sulfur contents. Hardness showed linear trends, while rupture energy was nonlinear.
Vinícius Guedes Gobbi, Ester Costa de Almeida, Roberta Helena Mendonça, Marysilvia Ferreira da Costa   +3 more
wiley   +1 more source

Model Regresi Partial Least Squares (Pls) (Studi Kasus : Kinerja Satuan Kerja Sekretariat Daerah Kabupaten Tegal) [PDF]

, 2009
Metode regresi kuadrat terkecil parsial atau Partial Least Squares (PLS) adalah pemodelan ‘lunak' yang bebas asumsi sebaran. PLS dilakukan secara iteratif menggunakan algoritma NIPALS dan proses pendugaannya melibatkan variansi variabel Y dan variansi ...
Tahyudin, I. (Imam)
core  

A sparse PLS for variable selection when integrating omics data [PDF]

, 2008
Recent biotechnology advances allow for multiple types of omics data, such as transcriptomic, proteomic or metabolomic data sets to be integrated. The problem of feature selection has been addressed several times in the context of classification, but ...
Besse, Philippe, Lê Cao, Kim-Anh, Robert-Granié, Christèle, Rossouw, Debra   +3 more
core   +5 more sources

Climate Change Mitigation Takes the Lead: EU Taxonomy‐Aligned and Eligible Activities in Relation to Debt Financing

Business Strategy and the Environment, EarlyView.
ABSTRACT This study assesses the degree of alignment with and eligibility to the EU Taxonomy of non‐financial firms and investigates its relationship with their Cost of Debt (CoD). The empirical analysis is based on a sample of 306 non‐financial firms listed on the Stoxx Europe 600 Index across 15 European countries. Taxonomy‐related data were manually
Fabio Rizzato, Simona Fiandrino, Alberto Tonelli, Giorgia La Barbera   +3 more
wiley   +1 more source

Phase II Study of Radiotherapy and Temsirolimus versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma without MGMT Promoter Hypermethylation (EORTC 26082). [PDF]

, 2016
EORTC 26082 assessed the activity of temsirolimus in patients with newly diagnosed glioblastoma harboring an unmethylated O6 methylguanine-DNA-methyltransferase (MGMT) promoter.
Bady, P., Brandes, A.A., Campone, M., Frenel, J.S., Golfinopoulos, V., Gorlia, T., Hamou, M.F., Hegi, M.E., Homicsko, K., Hopkins, K., Kosch, M., Lhermitte, B., Marosi, C., Pesce, G., Platten, M., Ricard, D., Roth, P., Steuve, J., Stupp, R., Taphoorn, M.J., van den Bent, M.J., Villa, S., Weller, M., Weyerbrock, A., Wick, A., Wick, W.   +25 more
core   +2 more sources

Goal Displacement and Goal Conflicts in Circular Innovation Initiatives: Types and Mitigation Practices

Business Strategy and the Environment, EarlyView.
ABSTRACT Many firms set ambitious sustainability goals but these are frequently “displaced” by proxy goals that are easier to track and measure. However, the specific types of goal conflicts that follow from this displacement are poorly understood. We conducted a case study of circular innovation initiatives at a global MedTech company and identified ...
Wiebke Reim, Johan Frishammar, Debadrita Panda   +2 more
wiley   +1 more source

Development of a UV−Vis Spectroscopy Method Allied with Chemometrics for Simultaneous Analysis of Dexketoprofen Trometamol and Thiocolchicoside in Commercial Tablets

Trends in Pharmacy
Background: Herein, a simple UV–Vis spectrophotometric method coupled with che mometrics including principal component analysis (PCA) and partial least squares (PLS) regression/prediction analysis was utilized for the simultaneous determina tion of ...
Nilay Öncel, Sema Nur Dal, Selen Duygu Çeçen, Fatma Nur Arslan   +3 more
doaj   +5 more sources