Results 61 to 70 of about 3,638 (166)

Evaluation of pre-test counselling offered for non-invasive prenatal testing (NIPT) as a primary screening tool

Journal of Obstetrics and Gynaecology, 2023
The increasing popularity and expansion of non-invasive prenatal testing (NIPT) to screen for rare conditions beyond common trisomies prompts evaluation of pre-test counselling currently offered.
Ho Yin Diana Lee, Lin Wai Chan
doaj   +1 more source

Blood Speckle Imaging as a Novel Adjunct in the Prenatal Assessment of Congenital Heart Disease: Insights From Aortic Arch Pathology and Septal Defects

Clinical Case Reports, Volume 14, Issue 4, April 2026.
Blood Speckle Imaging (BSI) is an innovative fetal echocardiography technique that enables the acquisition of high frame rate images and tracks moving blood cells. In a case initially suspected of interrupted aortic arch, BSI provided crucial additional insights, leading to a revised diagnosis.
Sarah van den Wildenberg, Andrea Stoop‐Berends, Ingrid M. van Beynum, Bas R. Rebel, Attie T. J. I. Go, Eric A. P. Steegers, Jérôme M. J. Cornette   +6 more
wiley   +1 more source

An Unusual Case of Citrobacter koseri Infection During Pregnancy at 27 Weeks: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Early prenatal screening at 26 + 6 weeks detected Citrobacter koseri vaginal colonization in an asymptomatic high‐risk gravida. Culture‐guided IV ceftazidime (susceptible per CLSI testing) eradicated the pathogen without maternal/fetal compromise.
Mario Assenza, Michele Caramia, Jacopo Wabersich   +2 more
wiley   +1 more source

Finding out the “gender” sooner: Ethical tensions and parental motivation in discovering fetal sex and chromosomal anomaly risk using noninvasive prenatal testing (NIPT)

SSM: Qualitative Research in Health
Noninvasive prenatal testing (NIPT) has rapidly expanded in both utilization and scope since it became available in 2011. While NIPT screens for a limited number of chromosomal anomalies, it has become colloquially known as the “gender” test because of ...
Aleksa Owen, G. Allen Ratliff
doaj   +1 more source

Single‐cell‐based non‐invasive screening for fetal pathogenic microimbalances using maternal blood: comparison with invasive prenatal diagnosis

Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 4, Page 500-509, April 2026.
ABSTRACT Objective Pathogenic or likely pathogenic copy‐number variants (p/lpCNVs) are a significant cause of perinatal morbidity and mortality. Current prenatal screening based on cell‐free DNA (cfDNA) fails to detect the majority of microimbalances (microdeletions/microduplications), leaving a significant residual risk of undetected chromosomal ...
T. Stampalija, C. Forcato, F. R. Grati, P. Volpe, V. De Robertis, C. Izzi, E. Bertucci, I. Fabietti, A. Novelli, S. Ornaghi, L. Pasquini, E. Bevilacqua, D. Paladini, T. Ghi, D. Lattuada, M. Dori, D. Mercatelli, A. Dal Molin, G. Buson, C. Bolognesi, A. Doffini, T. J. Musci, E. Ferrazzi, Collaborators, Emilia Dora Giovannone, Chiara Mangano, Chiara Maranta, Camilla Amadesi, Antonio Brocco, Arianna Casadei, Melissa Garrì, Rebecca Maiocchi, Ilaria Molinaro, Elisa Ortolan, Angela Piano, Maria Chiara Iannitiello, Davide Lisi, Agnese Feresin, Paolo Gasparini, Camilla Fregona, Georgios Rembouskos, Franco Edoardo Odicino, Marino Signorelli, Alessandra Sponzilli, Fabio Facchinetti, Chiara Vassallo, Elena Nicastri, Maria Grazia Di Gregorio, Valeria Orlando, Sabrina Cozzolino, Maria Verderio, Giulia Masini, Chiara Franchi, Francesco Danilo Tiziano, Domizia Pasquetti, Giulia Biancotto, Francesca Della Sala, Nicola Volpe, Andrea Dall'Asta, Rosamaria Silipigni, Ilaria Catusi   +60 more
wiley   +1 more source

Placental insufficiency markers to assess the risk of non‐chromosomal genetic conditions in early‐onset fetal growth restriction

Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 4, Page 492-499, April 2026.
ABSTRACT Objectives To assess the value of placental insufficiency markers for estimating the risk of genetic anomalies in fetuses with isolated early‐onset fetal growth restriction (FGR), defined as an estimated fetal weight ≤ 3rd percentile diagnosed ≤ 28 + 6 weeks' gestation.
M. Armengol‐Alsina, E. Bonacina, M. Dalmau, J. Temprado, I. Valenzuela, M. Codina‐Solà, M. Viñas‐Jornet, C. Rodó, M. Mendoza, Collaborators, A. Casellas, E. Del Barco, A. Brox, M. San Jose, P. Diaz, E. Roldán, B. Serrano, N. Maiz   +17 more
wiley   +1 more source

Impact of National Screening Programs on Down syndrome prevalence and outcomes

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 4, Page 613-620, April 2026.
Over the past two decades, pregnancies with DS, prenatal diagnosis, and subsequent terminations have increased. Yet, the proportion continuing pregnancy after diagnosis and the prevalence of live‐ and stillbirths with DS have remained stable throughout the same period.
Cecilie Bryn Nordklev, Denise Reis Costa, Roy Miodini Nilsen, Nils‐Halvdan Morken, Siri Vangen, Vasilis Sitras   +5 more
wiley   +1 more source

Obstetric professionals’ perceptions of non-invasive prenatal testing for Down syndrome: clinical usefulness compared with existing tests and ethical implications

BMC Pregnancy and Childbirth, 2017
Background While non-invasive prenatal testing (NIPT) for fetal aneuploidy is commercially available in many countries, little is known about how obstetric professionals in non-Western populations perceive the clinical usefulness of NIPT in comparison ...
Olivia Miu Yung Ngan, Huso Yi, Samuel Yeung Shan Wong, Daljit Sahota, Shenaz Ahmed   +4 more
doaj   +1 more source

Cost-effectiveness of prenatal screening and diagnostic strategies for Down syndrome: A microsimulation modeling analysis.

PLoS ONE, 2019
OBJECTIVES:Down syndrome (DS) is the most frequently occurring fetal chromosomal abnormality and different prenatal screening strategies are used for determining risk of DS worldwide.
Wei Zhang, Tima Mohammadi, Julie Sou, Aslam H Anis   +3 more
doaj   +1 more source

Non-invasive prenatal testing to detect chromosome aneuploidies in 57,204 pregnancies

Molecular Cytogenetics, 2019
Background Non-invasive prenatal testing (NIPT) has been widely used to detect common fetal chromosome aneuploidies, such as trisomy 13, 18, and 21 (T13, T18, and T21), and has expanded to sex chromosome aneuploidies (SCAs) during recent years, but few ...
Ying Xue, Guodong Zhao, Hong Li, Qin Zhang, Jiafeng Lu, Bin Yu, Ting Wang   +6 more
doaj   +1 more source