Results 71 to 80 of about 3,827 (184)

Obstetric professionals’ perceptions of non-invasive prenatal testing for Down syndrome: clinical usefulness compared with existing tests and ethical implications

BMC Pregnancy and Childbirth, 2017
Background While non-invasive prenatal testing (NIPT) for fetal aneuploidy is commercially available in many countries, little is known about how obstetric professionals in non-Western populations perceive the clinical usefulness of NIPT in comparison ...
Olivia Miu Yung Ngan, Huso Yi, Samuel Yeung Shan Wong, Daljit Sahota, Shenaz Ahmed   +4 more
doaj   +1 more source

Cost-effectiveness of prenatal screening and diagnostic strategies for Down syndrome: A microsimulation modeling analysis.

PLoS ONE, 2019
OBJECTIVES:Down syndrome (DS) is the most frequently occurring fetal chromosomal abnormality and different prenatal screening strategies are used for determining risk of DS worldwide.
Wei Zhang, Tima Mohammadi, Julie Sou, Aslam H Anis   +3 more
doaj   +1 more source

Challenges and clinical implications of discordant non-invasive prenatal testing results: insights from two case studies [PDF]

Folia Medica
Non-invasive prenatal testing (NIPT) has transformed prenatal screening, offering high sensitivity and specificity in the detection of common fetal aneuploidies.
Slavyana Galeva, Boris Stoilov, Ekaterina Uchikova   +2 more
doaj   +3 more sources

The value of increasing sequencing depth for noninvasive prenatal screening for whole chromosomal aneuploidy

Scientific Reports
To evaluate the value of increasing sequencing depths of non-invasive prenatal testing (NIPT) for fetal chromosomal aneuploidies based on the semiconductor sequencing platform.
Dongmei Wang, Fangfang Guo, Yaping Hou, Haishan Peng, Tingting Hu, Jiexia Yang   +5 more
doaj   +1 more source

Introducing the non-invasive prenatal test for trisomy 21 in Belgium: a cost-consequences analysis

BMJ Open, 2014
Background The first- and second-trimester screening for trisomy 21 (T21) are reimbursed for all pregnant women in Belgium. Using a cut-off risk of 1:300 for T21, about 5% of all pregnant women are referred for definitive prenatal diagnosis using an ...
Mattias Neyt, Frank Hulstaert, Wilfried Gyselaers   +2 more
doaj   +1 more source

Non-invasive prenatal testing to detect chromosome aneuploidies in 57,204 pregnancies

Molecular Cytogenetics, 2019
Background Non-invasive prenatal testing (NIPT) has been widely used to detect common fetal chromosome aneuploidies, such as trisomy 13, 18, and 21 (T13, T18, and T21), and has expanded to sex chromosome aneuploidies (SCAs) during recent years, but few ...
Ying Xue, Guodong Zhao, Hong Li, Qin Zhang, Jiafeng Lu, Bin Yu, Ting Wang   +6 more
doaj   +1 more source

A new era in prenatal care: non-invasive prenatal testing in Switzerland

Swiss Medical Weekly, 2014
QUESTIONS UNDER STUDY: Prenatal care has been significantly influenced by the introduction of non-invasive prenatal testing (NIPT) for aneuploidies in 2012. The aim of this study was to describe the current impact of NIPT on prenatal care.
Gwendolin Manegold-Brauer, Anjeung Kang Bellin, Sinuhe Hahn, Christian De Geyter, Johanna Buechel, Irene Hoesli, Olav Lapaire   +6 more
doaj   +1 more source

Multiple pregnancies: Nordic perspective and challenges

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 6, Page 972-974, June 2026.
Vedran Stefanovic
wiley   +1 more source

The performance evaluation of NIPT for fetal chromosome microdeletion/microduplication detection: a retrospective analysis of 68,588 Chinese cases

Frontiers in Genetics
BackgroundChromosomal abnormalities are the main cause of birth defects in newborns. Since the inception of noninvasive prenatal testing (NIPT) technology, it has primarily been applied to the detection of common trisomy (T21, T18, T13).
Shichun Shen, Haimei Qi, Xianping Yuan, Jinhui Gan, Junkun Chen, Jungao Huang   +5 more
doaj   +1 more source

KF-NIPT: K-mer and fetal fraction-based estimation of chromosomal anomaly from NIPT data

BMC Bioinformatics
Non-Invasive Prenatal Testing (NIPT) is a technique that allows pregnant women to screen for chromosomal abnormalities in their developing fetus without the need for invasive procedures like amniocentesis or chorionic villus sampling. However, current methods to detect anomaly from maternal cell-free DNAs (cfDNAs) that are based on the sequence read ...
Dongin Kim, Ji Yeon Sohn, Jin Hee Cho, Ji-Hye Choi, Gwi-young Oh, Hyun Goo Woo   +5 more
openaire   +3 more sources