Results 61 to 70 of about 3,827 (184)

Detection of 21q11.2‐q22.11 deletions in a fetus by NIPT [PDF]

Journal of Clinical Laboratory Analysis, 2019
BackgroundNon‐invasive prenatal testing (NIPT) is extensively used in the detection of fetal trisomies 21, 18, and 13, which is promptly becoming a common clinical practice. Concerned about the clinical application of non‐invasive detection of the fetal autosomal duplications or deletion.Case PresentationA 34‐year‐old, healthy pregnant woman was ...
Yunyun Zheng, Biliang Chen, Shanning Wan, Hui Xu, Yinghui Dang, Tingting Song, Yu Li, Jianfang Zhang   +7 more
openaire   +2 more sources

Analysis of the accuracy of Z-scores of non-invasive prenatal testing for fetal Trisomies 13, 18, and 21 that employs the ion proton semiconductor sequencing platform

Molecular Cytogenetics, 2018
Background Non-invasive prenatal testing (NIPT) is frequently being used to screen for trisomies 13, 18 and 21 for prenatal diagnosis. However, NIPT performs poorly when compared with invasive testing and thus should not be used to diagnose trisomies ...
Yuan Tian, Linlin Zhang, Weifang Tian, Jinshuang Gao, Liting Jia, Shihong Cui   +5 more
doaj   +1 more source

Gendered and nongendered language in genetic counseling

Journal of Genetic Counseling, Volume 35, Issue 3, June 2026.
Abstract Language is essential to genetic counseling. Genetic counselors use language to accurately communicate complex medical phenomena and support patients' understanding and wellbeing. This qualitative descriptive study explored how practicing genetic counselors used gendered and non‐gendered language in patient interactions and the motivations ...
Helen Anderson, B. Ethan Coston, Tahnee Causey, Rachel Wood, John Quillin   +4 more
wiley   +1 more source

Finding out the “gender” sooner: Ethical tensions and parental motivation in discovering fetal sex and chromosomal anomaly risk using noninvasive prenatal testing (NIPT)

SSM: Qualitative Research in Health
Noninvasive prenatal testing (NIPT) has rapidly expanded in both utilization and scope since it became available in 2011. While NIPT screens for a limited number of chromosomal anomalies, it has become colloquially known as the “gender” test because of ...
Aleksa Owen, G. Allen Ratliff
doaj   +1 more source

Model-based analysis of costs and outcomes of non-invasive prenatal testing for Down's syndrome using cell free fetal DNA in the UK National Health Service.

PLoS ONE, 2014
BackgroundNon-invasive prenatal testing (NIPT) for Down's syndrome (DS) using cell free fetal DNA in maternal blood has the potential to dramatically alter the way prenatal screening and diagnosis is delivered. Before NIPT can be implemented into routine
Stephen Morris, Saffron Karlsen, Nancy Chung, Melissa Hill, Lyn S Chitty   +4 more
doaj   +1 more source

Free Fetal DNA Testing to Guide Early Intervention in the Management of the Kell Alloimmunized Pregnancy

Prenatal Diagnosis, EarlyView.
Kenneth J. Moise Jr, Thomas Trevett, Stephanie Moench, Erin Moise   +3 more
wiley   +1 more source

Semi‐Automated Platform for Early Prenatal Coelocentesis Testing Using Electrospun Nanofiber Technology

Macromolecular Materials and Engineering, Volume 311, Issue 6, June 2026.
A semi‐automated approach for early prenatal diagnosis is developed for low‐cellularity samples from coelocentesis by exploiting biotin/streptavidin interaction to functionalize electrospun mats with antibodies. With potential microfluidic integration, the resulting platform enables fetal cell capture, offering a strategy toward improved efficiency and
Emanuela Muscolino, Anna Barbara Di Stefano, Santina Acuto, Clelia Dispenza   +3 more
wiley   +1 more source

Multi‐Omics Reveals Early Pregnancy Placental Dysfunction Associated With Preterm and Term Preeclampsia

MedComm, Volume 7, Issue 6, June 2026.
Preeclampsia, a severe pregnancy‐induced disorder unique to humans, affects ∼5% of pregnancies globally. To understand the pathogenesis of preeclampsia, this study performed a comprehensive multi‐omics analysis of early pregnancy placental biopsies (chorionic villus samples) from pregnancies that later developed preterm/term preeclampsia, compared to ...
Ellen Menkhorst, Guannan Yang, Yimiao Yu, Leilani L. Santos, Wei Zhou, Argyro Syngelaki, Swati Varshney, Nicholas A. Williamson, Kaori Koga, Daniel Lorber Rolnik, Fabricio da Silva Costa, Kypros Nicolaides, Kim‐Anh Lê Cao, Evdokia Dimitriadis   +13 more
wiley   +1 more source

First‐Trimester Down Syndrome Screening in Renal‐Transplanted Pregnant Women: Blood Creatinine Levels Impact False‐Positive Rate

Prenatal Diagnosis, Volume 46, Issue 7, Page 993-999, June 2026.
ABSTRACT Objective Over the past few decades, several thousand pregnancies following kidney transplantation have been monitored but few studies have reported on first‐trimester Down syndrome screening. This study aimed to assess the performance of such screening and its relationship with renal function.
Clément Burgy, Lisa Chanourdie, Béatrice Guyard‐Boileau, Anne‐Laure Hebral, Annelise Genoux, Marie‐Sophie Combis, Paul Guerby, Christophe Vayssiere, Safouane M. Hamdi   +8 more
wiley   +1 more source

NIPT and the concerns regarding ‘routinisation’ [PDF]

European Journal of Human Genetics, 2022
openaire   +2 more sources