Results 51 to 60 of about 1,617 (165)
Effectiveness of nirsevimab immunization against RSV infection in preterm infants: a systematic review and meta-analysis
Frontiers in ImmunologyBackgroundRespiratory Syncytial Virus (RSV) is one of the primary pathogen responsible for severe lower respiratory tract infections in preterm infants, placing a significant burden on patients, their families, and society.Xiaopeng Wang, Xiaopeng Wang, Xiaopeng Wang, Li Kong, Li Kong, Li Kong, Xueou Liu, Panpan Wu, Panpan Wu, Panpan Wu, Lulu Zhang, Lulu Zhang, Lulu Zhang, Fangrui Ding, Fangrui Ding, Fangrui Ding +15 moredoaj +1 more sourceRespiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control
Medicinal Research Reviews, Volume 46, Issue 3, Page 672-712, May 2026.ABSTRACT
Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei +6 morewiley +1 more sourceIncidence of Respiratory Syncytial Virus Infection Among Patients Aged Less Than 2 Years: A Retrospective Study From an Italian Southern Region in Years 2018–2023
Influenza and Other Respiratory Viruses, Volume 20, Issue 5, May 2026.ABSTRACT Introduction
Respiratory syncytial virus (RSV) is one of the most common viruses infecting nearly all children worldwide within the first 2 years of life, requiring hospitalization for over 80% of cases in infants under the age of 1. The aim of this study was to evaluate the epidemiological impact of RSV infections on hospital admissions among Giuseppe Di Martino, Pamela Di Giovanni, Federica Vaccaro, Francesca Romana Cascavilla, Carla Di Marzio, Livia Tognaccini, Edoardo Trebbi, Teresa Aita, Ferdinando Romano, Tommaso Staniscia +9 morewiley +1 more sourceExpanded Genomic Surveillance and Seasonal Comparisons of Human Respiratory Syncytial Virus Infections in Minnesota, USA, 2023–2025
Influenza and Other Respiratory Viruses, Volume 20, Issue 5, May 2026.ABSTRACT Background
Human respiratory syncytial virus (HRSV) imposes a substantial burden in the United States. The use of whole‐genome sequencing (WGS) for public health surveillance of HRSV lags that for other viral pathogens. The objective of this study was to expand the scope and depth of WGS‐based surveillance of HRSV in Minnesota, USA.Daniel Evans, Henry Kunerth, Erica Mumm, Matthew Plumb, Laura Bohnker‐Voels, Sarah Bistodeau, Scott A. Cunningham, Jordan Davis, Karen Martin, Kathryn Como‐Sabetti, Sarah Namugenyi, Xiong Wang, Ruth Lynfield, Anna Strain, Sara Vetter +14 morewiley +1 more sourcePopulation Pharmacokinetics of Clesrovimab in Preterm and Full‐Term Infants
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1036-1046, April 2026.Clesrovimab is a half‐life extended monoclonal antibody targeting the respiratory syncytial virus fusion protein. Three studies (phase Ib/IIa [MK‐1654‐002], phase IIb/III [CLEVER], and phase III [SMART]) were conducted to evaluate the efficacy, safety, and pharmacokinetics (PK) of clesrovimab in infants.Ziheng Hu, Farina Hellmann, Xiaowei Zang, Nele Plock, Keyur Parmar, Radha A. Railkar, S. Y. Amy Cheung, Brian M. Maas, Ferdous Gheyas +8 morewiley +1 more sourceReal-world emergence of nirsevimab resistance in breakthrough infections with respiratory syncytial virus-B: a multicentre observational study in France
The Lancet MicrobeSummary: Background: Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection in infants. Nirsevimab, a long-acting monoclonal antibody targeting a conserved epitope on the prefusion F protein (site Φ), has shown high ...ProfPhD Slim Fourati, Alawiya Reslan, PhD, Jérôme Bourret, PhD, Jean-Sébastien Casalegno, PhD, Yannis Rahou, Laurent Softic, PhD, Lionel Chollet, MD, Pauline Trémeaux, PhD, ProfPhD Berthe-Marie Imbert-Marcille, PhD, Sylvie Pillet, PhD, Nicolas Veyrenche, PhD, Agathe Boudet, PhD, Luc Deroche, MD, ProfPhD Sonia Burrel, MD, Lina Mouna, PharmD, Theophile Cocherie, MD, Aurélie Schnuriger, PhD, Charlotte Pronier, PhD, Lynda Handala, PharmD, Véronique Brodard, PhD, Floriane Gallais, PhD, Sylvie Larrat, PhD, Alexandre Regueme, PharmD, Nefert Candace Dossou, PharmD, Amandine Henry, PharmD, ProfPhD Elyanne Gault, PharmD, Cédric Hartard, PhD, Ségolène Brichler, PhD, Alice Moisan, PhD, ProfPhD Véronique Avettand-Fenoel, PhD, Caroline Lefeuvre, PharmD, Ilka Engelmann, PhD, ProfPhD Sandrine Castelain, PhD, Audrey Mirand, PhD, Maud Salmona, PhD, Marie-Christine Jaffar-Bandjee, PhD, Mohamed Ader, Sarah Seng, Pierre Cappy, PhD, ProfPhD Christophe Rodriguez, PhD, Arnaud Ly, Georges Dos Santos, PhD, ProfPhD Olivier Schwartz, PhD, Chloé Petiot, Delphine Planas, PhD, Samar Berreira Ibraim, PhD, Kévin Da Silva, PhD, Amélie Recoing, MD, ProfPhD Jean-Michel Pawlotsky, MD, Frédéric Lemoine, PhD, ProfPhD Etienne Audureau, PhD, ProfPhD Marie-Anne Rameix-Welti, PhD, Naël Zemali, Sonia Burrel, Pantxika Bellecave, Alice Moisan, Zakasoa-Mbololona Zavaoarisaina, Romain Legros, Boris Derman, Vincent Pargny, Hortense Petat, Jean-Christophe Plantier, Véronique Avettand-Fenoel, Salim Ferrani, Jérome Guinard, Clémence Guillaume, Gilbert Mchantaf, Victoria Marie, Laurent Bret, Fabien Lesne, Anthony de Oliveira, Alexandre Regueme, Kazali Alidjinou, Lionel Chollet, Vincent Gardan, Ségolène Brichler, Loic de Pontual, Camille Aupiais, Stéphane Marot, Aurélie Schnuriger, Marine Perrier, Pierre Jatteau, Djeneba Fofana, Théophile Cocherie, Elisa Teyssou, Cathia Soulié, Vincent Calvez, Sylvie Larrat, Anne Faisant, Guillaume Mortamet, Caroline Tournegros, Mohamed Habib, Sylvie Pillet, Aymeric Cantais, Franck Zekre, Thomas Bourlet, Oulfa Boussetta-Charfi, Sara Chenafi-Adham, Eva Gleizes, Cédric Hartard, Caroline Lefeuvre, Elise Bouthry, Lina Mouna, Fairly Warnakulasuriya, Quentin Le Hingrat, Marie-Christine Jaffar-Bandjee, Diana Heaugwane, Benjamin Azemar, Nicolas Mnemosyme, Laurent Souply, Catherine François, Sandrine Castelain, Cinthia Rames, Arnaud Bécourt, Ilka Engelmann, Eric Jeziorski, Vincent Foulongne, Lynda Handala, Catherine Gaudy-Graffin, Agathe Crémadés, Amandine Henry, Alessandra Pennisi, Maud Salmona, Jérôme Le Goff, Audrey Gabassi, Marie-Laure Néré, Marine Minier, Audrey Baron, Stéphane Bonacorsi, Naim Ouldali, Abdeljalil Senhaji Rachik, Marie-Anne Rameix-Welti, Alawyia Reslan, Yannis Rahou, Banujaa Jeyarajah, Anne Huard de Verneuil, Jérome Bourret, Frédéric Lemoine, Kévin Da Silva, Samar Berreira Ibraim, Vincent Enouf, Danielle Perez-Bercoff, Lucy Mosscrop, Etienne Simon-Loriere, Nefert Candace Dossou, Astrid Vabret, Slim Fourati, Christophe Rodriguez, Jean-Michel Pawlotsky, Pierre Cappy, Alexandre Soulier, Mohamed Ader, Sarah Seng, Arnaud Ly, Amandine Caillault, Pierre-André Natella, Etienne Audureau, Georges Dos Santos, Laurence Fagour, Anne-Julie Schapira, Olivier Flechelles, Luc Deroche, Nicolas Lévêque, Claire Morton Fauche, Sarah Borel, Erwan Ripley, Juliette Aubin, Berthe-Marie Imbert, Louise Castain, Audreay Rodallec, Justine Sourice, Christele Gras-Le Guen, Anne Chauvire-Drouard, Elyanne Gault, Frédérique Moreau, Claire Deback, Floriane Gallais, Morgane Solis, Valentin Stephan, Léa Pilorgé, Sophie Vallet, Léa Gaitan, Sylvie Rogez, Audrey Mirand, Cecile Henquell, Charlotte Pronier, Claire Grolhier, Vincent Thibault, Pauline Trémeaux, Isabelle Claudet, Mélanie Pucelle, Laetitia Staes, Camille Vellas, Sofia Demmou, Romain Carcenac, Nicolas Veyrenche, Jean-sébastien Casalegno, Alexandre Gaymard, Jose Kombou, Antonin Bal, Stanislas Ogoudjobi, Agathe Boudet, Amélie Recoing +202 moredoaj +1 more sourceMaternal RSV vaccination for infant protection: A systematic review and meta‐analysis of phase 3 trials with an integrated economic evaluation
International Journal of Gynecology &Obstetrics, Volume 173, Issue 1, Page 63-73, April 2026.Abstract Background
Respiratory syncytial virus (RSV) is a leading cause of hospitalization and mortality in early infancy. Maternal immunization offers a preventive strategy, but uncertainties regarding safety and economic value have limited its implementation.Johnatan Torres‐Torres, Lourdes Rojas‐Zepeda, José Rafael Villafan‐Bernal, Raigam Martinez‐Portilla, Salvador Espino‐y‐Sosa, Pablo Cerda‐Flores, Elsa Romelia Moreno‐Verduzco, Irma Eloisa Monroy‐Muñoz, Ameyran Yolanda Gonzalez‐Guerrero, Juan Mario Solis‐Paredes, Javier Perez Duran +10 morewiley +1 more sourceSociodemographic Characteristics of Infants Receiving Nirsevimab
JAMA Network OpenThis cohort study investigates inequalities by sociodemographic group in the receipt of nirsevimab immunization by infants in France from 2023 to 2024.Boutin, Salomé, Bertrand, Marion, Cohen, Jérémie F., Zureik, Mahmoud, Chalumeau, Martin, Jabagi, Marie-Joëlle +5 moreopenaire +2 more sourcesLow‐value care and variation in practice in the care of children hospitalized with bronchiolitis in Canada (CareBEST): Protocol for a multi‐center prospective cohort study
Journal of Hospital Medicine, Volume 21, Issue 4, Page 458-468, April 2026.Abstract Introduction
Low‐value care refers to health services for which the potential harms or costs outweigh the benefits of use. Bronchiolitis is the most common and among the most costly causes of pediatric hospitalizations. Evidence consistently shows that many common tests and treatments used to manage bronchiolitis do not improve outcomes ...Branden Bonham, Tamara Perez, Michelle Bailey, Nick Barrowman, Christopher Bonafide, Ariane Boutin, Melanie Buba, Francine Buchanan, Matthew Carwana, Breanna A. Chen, Evelyn Constantin, Kim de Castris Garcia, Francesca del Giorgio, Zachary Dionisopoulos, Christine Fahim, Karen L. Forbes, Jeremy N. Friedman, Josée Anne Gagnon, Peter J. Gill, Mei Han, Nelly Huynh, Maria Karaceper, Terry P. Klassen, Isabelle Lahaie, Patricia Li, Myla Moretti, Sanjay Mahant, Sarah Manos, Hayat Mekhici, Chris Novak, Olivia Ostrow, Caroline Quach, Julie Quet, Mahmoud Sakran, Anupam Seghal, Alan R. Shroeder, Marc‐André Turcot, Gita Wahi, Olivier Drouin, The Canadian Pediatric Inpatient Research Network (PIRN) +39 morewiley +1 more source
