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Impact du nirsevimab sur les infections pédiatriques au VRS en Belgique en 2024-2025 : une analyse des données de surveillance sentinelle de routine de Sciensano
Nous estimons que 35 à 45 % des hospitalisations ont été évitées grâce à l’introduction du nirsevimab.
Nous estimons que l’introduction du nirsevimab a permis de diminuer de 35 à 45 % les hospitalisations liées à une infection au VRS chez les enfants de ...T. Braeye, A. Lajot, L. Cornelissen, L. De Mot, S. Hanoteaux, Y. Dockx, B.E.L.S.A.R.I.N.E.Tresearch group, S. Denayer, Y. Lafort, I. Van Evercooren, M. Fonnesu, Y. Dupont, K. Blot, M. Vandromme, P. Mpakaniye, M.U. Paz +15 morecore +1 more sourceImpact van nirsevimab op pediatrische RSV-infecties in België in 2024-2025. Een analyse van de routine sentinel-surveillancegegevens van Sciensano
We schatten dat 35 tot 45% van de ziekenhuisopnames is voorkomen door de introductie van nirsevimab.
We schatten dat de introductie van nirsevimab heeft geleid tot 35-45% minder ziekenhuisopnames voor een RSV-infectie bij kinderen jonger dan 5 jaar.T. Braeye, A. Lajot, L. Cornelissen, L. De Mot, S. Hanoteaux, Y. Dockx, B.E.L.S.A.R.I.N.E.Tresearch group, S. Denayer, Y. Lafort, I. Van Evercooren, M. Fonnesu, Y. Dupont, K. Blot, M. Vandromme, P. Mpakaniye, M.U. Paz +15 morecore +1 more sourceReal-world emergence of nirsevimab resistance in breakthrough infections with respiratory syncytial virus-B: a multicentre observational study in France
The Lancet MicrobeSummary: Background: Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection in infants. Nirsevimab, a long-acting monoclonal antibody targeting a conserved epitope on the prefusion F protein (site Φ), has shown high ...ProfPhD Slim Fourati, Alawiya Reslan, PhD, Jérôme Bourret, PhD, Jean-Sébastien Casalegno, PhD, Yannis Rahou, Laurent Softic, PhD, Lionel Chollet, MD, Pauline Trémeaux, PhD, ProfPhD Berthe-Marie Imbert-Marcille, PhD, Sylvie Pillet, PhD, Nicolas Veyrenche, PhD, Agathe Boudet, PhD, Luc Deroche, MD, ProfPhD Sonia Burrel, MD, Lina Mouna, PharmD, Theophile Cocherie, MD, Aurélie Schnuriger, PhD, Charlotte Pronier, PhD, Lynda Handala, PharmD, Véronique Brodard, PhD, Floriane Gallais, PhD, Sylvie Larrat, PhD, Alexandre Regueme, PharmD, Nefert Candace Dossou, PharmD, Amandine Henry, PharmD, ProfPhD Elyanne Gault, PharmD, Cédric Hartard, PhD, Ségolène Brichler, PhD, Alice Moisan, PhD, ProfPhD Véronique Avettand-Fenoel, PhD, Caroline Lefeuvre, PharmD, Ilka Engelmann, PhD, ProfPhD Sandrine Castelain, PhD, Audrey Mirand, PhD, Maud Salmona, PhD, Marie-Christine Jaffar-Bandjee, PhD, Mohamed Ader, Sarah Seng, Pierre Cappy, PhD, ProfPhD Christophe Rodriguez, PhD, Arnaud Ly, Georges Dos Santos, PhD, ProfPhD Olivier Schwartz, PhD, Chloé Petiot, Delphine Planas, PhD, Samar Berreira Ibraim, PhD, Kévin Da Silva, PhD, Amélie Recoing, MD, ProfPhD Jean-Michel Pawlotsky, MD, Frédéric Lemoine, PhD, ProfPhD Etienne Audureau, PhD, ProfPhD Marie-Anne Rameix-Welti, PhD, Naël Zemali, Sonia Burrel, Pantxika Bellecave, Alice Moisan, Zakasoa-Mbololona Zavaoarisaina, Romain Legros, Boris Derman, Vincent Pargny, Hortense Petat, Jean-Christophe Plantier, Véronique Avettand-Fenoel, Salim Ferrani, Jérome Guinard, Clémence Guillaume, Gilbert Mchantaf, Victoria Marie, Laurent Bret, Fabien Lesne, Anthony de Oliveira, Alexandre Regueme, Kazali Alidjinou, Lionel Chollet, Vincent Gardan, Ségolène Brichler, Loic de Pontual, Camille Aupiais, Stéphane Marot, Aurélie Schnuriger, Marine Perrier, Pierre Jatteau, Djeneba Fofana, Théophile Cocherie, Elisa Teyssou, Cathia Soulié, Vincent Calvez, Sylvie Larrat, Anne Faisant, Guillaume Mortamet, Caroline Tournegros, Mohamed Habib, Sylvie Pillet, Aymeric Cantais, Franck Zekre, Thomas Bourlet, Oulfa Boussetta-Charfi, Sara Chenafi-Adham, Eva Gleizes, Cédric Hartard, Caroline Lefeuvre, Elise Bouthry, Lina Mouna, Fairly Warnakulasuriya, Quentin Le Hingrat, Marie-Christine Jaffar-Bandjee, Diana Heaugwane, Benjamin Azemar, Nicolas Mnemosyme, Laurent Souply, Catherine François, Sandrine Castelain, Cinthia Rames, Arnaud Bécourt, Ilka Engelmann, Eric Jeziorski, Vincent Foulongne, Lynda Handala, Catherine Gaudy-Graffin, Agathe Crémadés, Amandine Henry, Alessandra Pennisi, Maud Salmona, Jérôme Le Goff, Audrey Gabassi, Marie-Laure Néré, Marine Minier, Audrey Baron, Stéphane Bonacorsi, Naim Ouldali, Abdeljalil Senhaji Rachik, Marie-Anne Rameix-Welti, Alawyia Reslan, Yannis Rahou, Banujaa Jeyarajah, Anne Huard de Verneuil, Jérome Bourret, Frédéric Lemoine, Kévin Da Silva, Samar Berreira Ibraim, Vincent Enouf, Danielle Perez-Bercoff, Lucy Mosscrop, Etienne Simon-Loriere, Nefert Candace Dossou, Astrid Vabret, Slim Fourati, Christophe Rodriguez, Jean-Michel Pawlotsky, Pierre Cappy, Alexandre Soulier, Mohamed Ader, Sarah Seng, Arnaud Ly, Amandine Caillault, Pierre-André Natella, Etienne Audureau, Georges Dos Santos, Laurence Fagour, Anne-Julie Schapira, Olivier Flechelles, Luc Deroche, Nicolas Lévêque, Claire Morton Fauche, Sarah Borel, Erwan Ripley, Juliette Aubin, Berthe-Marie Imbert, Louise Castain, Audreay Rodallec, Justine Sourice, Christele Gras-Le Guen, Anne Chauvire-Drouard, Elyanne Gault, Frédérique Moreau, Claire Deback, Floriane Gallais, Morgane Solis, Valentin Stephan, Léa Pilorgé, Sophie Vallet, Léa Gaitan, Sylvie Rogez, Audrey Mirand, Cecile Henquell, Charlotte Pronier, Claire Grolhier, Vincent Thibault, Pauline Trémeaux, Isabelle Claudet, Mélanie Pucelle, Laetitia Staes, Camille Vellas, Sofia Demmou, Romain Carcenac, Nicolas Veyrenche, Jean-sébastien Casalegno, Alexandre Gaymard, Jose Kombou, Antonin Bal, Stanislas Ogoudjobi, Agathe Boudet, Amélie Recoing +202 moredoaj +1 more sourceResults From the Third and Fourth WHO External Quality Assessments for the Molecular Detection of Respiratory Syncytial Virus
Influenza and Other Respiratory Viruses, Volume 20, Issue 8, August 2026.ABSTRACT Background
In 2016, the World Health Organization (WHO) initiated the global RSV surveillance programme, which aimed to strengthen laboratory diagnostic capacity and evaluate molecular detection test performance. External quality assessments (EQAs) are conducted regularly as part of this programme to ensure ongoing laboratory proficiency.Fernando do Couto Motta, Obadiah Kenji, Ian Barr, Shabana Bi, Anne von Gottberg, Jean‐Michel Heraud, Siddhi Hirve, Sanjiv Rughooputh, Nicole Wolter, Maria Zambon, Thomas C. Williams, Wenqing Zhang +11 morewiley +1 more sourceEvaluating Analytic Approaches to Determining Respiratory Syncytial Virus Seasonality—United States, 2014–2024
Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.ABSTRACT Background
Respiratory syncytial virus (RSV) is a major cause of hospitalizations among infants and older adults in the United States. Determining RSV seasonality, which varies geographically, is essential to the timely administration of prevention products.Sophia Chkonia, Sarah Hamid, Erica Billig Rose, Amber Winn, Erin Anderson, Benjamin J. Silk +5 morewiley +1 more sourceCorrelations and Timeliness of Respiratory Syncytial Virus Surveillance Indicators—United States, 2018–2024
Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.ABSTRACT Background
Respiratory syncytial virus (RSV) is a major cause of hospitalizations in young children and older adults in the United States. Monitoring seasonal RSV activity through national surveillance systems and understanding the relationships among RSV surveillance indicators can help ensure timely administration of prevention products and ...Erin L. Anderson, Erica Billig Rose, Amber Winn, Sophia Chkonia, Heidi Moline, Ariana Toepfer, Monica E. Patton, Christopher A. Taylor, Aaron Kite‐Powell, Stephanie Dietz, Michael Sheppard, Jourdan DeVies, Benjamin J. Silk +12 morewiley +1 more sourceGuideline for the Diagnosis and Management of Heritable IFNAR1 Deficiency in Oceania
Journal of Paediatrics and Child Health, Volume 62, Issue 7, Page 1113-1120, July 2026.ABSTRACT
Autosomal recessive interferon alpha and beta receptor subunit 1 (IFNAR1) deficiency is a rare and heritable inborn error of immunity (IEI) predisposing individuals to severe and life‐threatening viral infections. It is more common in people of Western Polynesian ancestry, with estimates of around one in six thousand live births affected, due ...Cecilia Verryt, Paul Gray, Peter McNaughton, Jane Peake, Melanie Wong, George Aho, Emma Best, Maia Brewerton, Flora Lutui, Litara Esera Tulifau, Rebecca Qin, Satupa‘itea Viali, Petine White, Andrew Wood, See‐Tarn Woon, Theresa Cole, Alberto Pinzon Charry, Kuang‐Chih Hsiao +17 morewiley +1 more sourceInfants needed to immunise with nirsevimab to prevent one RSV hospitalisation, Spain, 2023/24 season
The study was funded by the Institute of Health Carlos III (on its own budget) which, at the institutional level, had no role in the study design, data collection, analysis or interpretation.Using real-life data from Spain between October 2023 and March ...Nuñez, Olivier, Pastor-Barriuso, Roberto, Monge Corella, Susana, Nirsevimab Effectiveness Study Collaborators, Jarrin Vera, Inmaculada +4 morecore +1 more source
