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Nirsevimab for preventing respiratory syncytial virus lower respiratory tract infections in infants: a systematic review and meta-analysis
Frontiers in Public HealthBackgroundRespiratory syncytial virus (RSV) causes lower respiratory tract infections (LRTIs) in infants, leading to substantial morbidity and mortality. Nirsevimab, a long-lasting monoclonal antibody, has been demonstrated to reduce RSV-related outcomes Samira Soudani, Lorenzo Bertizzolo, Mehdi Ghemmouri, Mary Chappell, Rachael McCool, Katie Reddish, Paul Miller, Erin Barker, Harriet Fewster +8 moredoaj +1 more sourceGenotypic and phenotypic characterisation of respiratory syncytial virus after nirsevimab breakthrough infections: a large, multicentre, observational, real-world study
International audienceBackgroundNirsevimab, a long-acting monoclonal antibody, has been approved for the prevention of respiratory syncytial virus (RSV) infection in infants.Morton Fauche, Claire, Derman, Boris, Azemar, Benjamin, Guinard, Jérome, Yab, Emilie, Reslan, Alawyia, Mouna, Lina, Gras-Le Guen, Christele, Flechelles, Olivier, Dossou, Nefert Candace, Brichler, Ségolène, Jatteau, Pierre, Rahou, Yannis, Calvez, Vincent, dos Santos, Georges, Gabassi, Audrey, Fourati, Slim, Plantier, Jean-Christophe, Prot, Matthieu, Legros, Romain, Moreau, Frédérique, Cantais, Aymeric, Bouthry, Elise, Crémadés, Agathe, Gault, Elyanne, Francois, Catherine, Cocherie, Théophile, Boussetta-Charfi, Oulfa, da Silva, Kévin, Schnuriger, Aurélie, Salmona, Maud, Thibault, Vincent, Zemali, Nael, Gaymard, Alexandre, Mnemosyme, Nicolas, Mortamet, Guillaume, Pronier, Charlotte, Bal, Antonin, Bret, Laurent, Avettand-Fenoel, Véronique, Gaitan, Léa, Pawlotsky, Jean-Miichel, Soulié, Cathia, Gallais, Floriane, Bourlet, Thomas, Carcenac, Romain, Simon-Loriere, Etienne, Schwartz, Olivier, Le Goff, Jérôme, Natella, Pierre-André, Staes, Laetitia, Handala, Lynda, Lemoine, Frédéric, Fagour, Laurence, Moisan, Alice, Rogez, Sylvie, Lemoine, Frédérique, Fofana, Djeneba, Ly, Arnaud, Tournegros, Caroline, Rodallec, Audreay, Rachik Abdeljalil, Senhaji, Henry, Steven, Hartard, Cédric, Castain, Louise, Claudet, Isabelle, Audureau, Etienne, Ferrani, Salim, Vallet, Sophie, Castelain, Sandrine, Jeziorski, Eric, Lefeuvre, Caroline, Buchrieser, Julian, Pillet, Sylvie, Veyrenche, Nicolas, Henquell, Cecile, Burrel, Sonia, Mafi, Sarah, Lesne, Fabien, Warnakulasuriya, Fairly, Pilorgé, Léa, Guillaume, Clémence, Jaffar, Marie-Christine, de Pontual, Loic, Bonacorsi, Stéphane, Petat, Hortense, Domitien, Léa, Ader, Mohamed, Regueme, Alexandre, Teyssou, Elisa, Bourret, Jérome, Ouldali, Naim, Foulongne, Vincent, Berreira Ibraim, Samar, Marie, Victoria, Rames, Cinthia, Pawlotsky, Jean-Michel, Tremeaux, Pauline, Enouf, Vincent, Schapira, Anne-Julie, Henry, Amandine, Zekre, Franck, Leveque, Nicolas, Heaugwane, Diana, Rodriguez, Christophe, Zavaoarisaina, Zakasoa-Mbololona, Gaudy-Graffin, Catherine, Vellas, Camille, Perrier, Marine, Néré, Marie-Laure, Vabret, Astrid, Chenafi-Adham, Sara, Le Hingrat, Quentin, Ogoudjobi, Stanislas, Solis, Morgane, Alidjinou, Kazali, Engelmann, Ilka, Rameix-Welti, Marie-Anne, Habib, Mohamed, Marot, Stéphane, Mchantaf, Gilbert, de Oliveira, Anthony, Faisant, Anne, Imbert-Marcille, Berthe-Marie, Gleizes, Eva, Donati, Flora, Deback, Claire, Deroche, Luc, Jeyarajah, Banujaa, Pucelle, Mélanie, Sourice, Justine, Jaffar-Bandjee, Marie-Christine, Soulier, Alexandre, Seng, Sarah, Reslan, Alawiya, Larrat, Sylvie, Souply, Laurent, Pennisi, Alessandra, Kombou, Jose, Aupiais, Camille, Pargny, Vincent, Mirand, Audrey, Cappy, Pierre, Chollet, Lionel, Chauvire-Drouard, Anne, Gardan, Vincent, Bécourt, Arnaud, Casalegno, Jean-Sébastien, Stephan, Valentin, Imbert, Berthe-Marie +149 morecore +1 more sourceChanges in Respiratory Syncytial Virus‐Associated Hospitalisations Epidemiology After Nirsevimab Introduction in Lyon, France
International audienceBackground Respiratory Syncytial Virus (RSV) is a major health concern, particularly for infants. In France, Nirsevimab, a long‐acting monoclonal antibody to prevent RSV‐associated lower respiratory tract infections (LRTI) was ...Ploin, Dominique, Butin, Marine, Horvat, Côme, Javouhey, Etienne, Hassenboehler, Juliette, Casalegno, Jean‐sebastien, Gillet, Yves, Plaisant, Franck, Ragouilliaux, Corinne, Nunes, Marta C., Chauvel, Cécile, Chakra, Claire Nour Abou +11 morecore +1 more sourceAssessment of effectiveness and impact of universal prophylaxis with nirsevimab for prevention of hospitalizations due to respiratory syncytial virus in infants. The NIRSE-GAL study protocol
Human Vaccines & ImmunotherapeuticsNirsevimab has been recently licensed for universal RSV prophylaxis in infants. NIRSE-GAL is a three-year population-based study initiated in Galicia in September 2023.Narmeen Mallah, Sonia Ares-Gómez, Jacobo Pardo-Seco, Alberto Malvar-Pintos, María-Isolina Santiago-Pérez, Olaia Pérez-Martínez, María-Teresa Otero-Barrós, Nuria Suárez-Gaiche, Rolf Kramer, Jing Jin, Leticia Platero-Alonso, Rosa-María Alvárez-Gil, Olga-María Ces-Ozores, Victoria Nartallo-Penas, Susana Mirás-Carballal, Marta Piñeiro-Sotelo, Juan-Manuel González-Pérez, Carmen Rodríguez-Tenreiro, Irene Rivero-Calle, Antonio Salas, Carmen Durán-Parrondo, Federico Martinón-Torres +21 moredoaj +1 more source