Results 51 to 60 of about 242,031 (247)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Agronomy, 2021 Urea fertilizer as a nitrogen source is used widely and globally. However, N loss through ammonia volatilization from applied urea has become a major drawback to agriculture. A pot experiment was conducted to determine the effect of rice straw biochar on
Gunavathy Selvarajh, Huck Ywih Ch’ng
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Acta Crystallographica Section E Structure Reports Online, 2009 En el compuesto del título,C4H9N2O3 +·NO3−, alternativamente llamado nitrato de (1RS) -2-carbamoil-1-carboxietanaminio, la unidad asimétrica comprende un catión asparaginio y un anión nitrato. El enlace de hidrógeno O—HO catiónico más fuerte en la estructura, junto con otros enlaces de hidrógeno N—HO catiónicos fuertes, genera una sucesión de cadenas ...
Nabila Moussa Slimane +4 more
openaire +3 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Frontiers in Environmental ScienceMachine learning (ML) models have proven to be an efficient technique for better understanding and quantification of surface water quality, especially in agricultural watersheds where considerable anthropogenic activities occur.
Ahmed Elsayed +5 more
doaj +1 more source
2,4,6-Trimethylpyridinium nitrate [PDF]
Acta Crystallographica Section E Structure Reports Online, 2010 في مركب العنوان، C(8)H(12)N (+) ·NO(3) (-)، يقع الكاتيون على مستوى مرآة وتقع ذرة N و C واحدة على محور مزدوج. في البلورة، ترتبط الأنيونات والكاتيونات بتفاعلات N - HO على طول المحور b ويحدث أيضًا اتصال قصير n - o OP [3.2899 (5) Å].
Shahzad Sharif +4 more
openaire +4 more sources