Results 71 to 80 of about 857,936 (311)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

For a Better Understanding of the Effect of N Form on Growth and Chemical Composition of C₃ Vascular Plants under Elevated CO₂—A Case Study with the Leafy Vegetable Eruca sativa

Horticulturae, 2021
Plant responses to elevated atmospheric CO2 (eCO2) are well studied, but the interactions of the carbon and nitrogen metabolism in the process are still not fully revealed.
Lilian Schmidt, Jana Zinkernagel
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Atmospheric oxidation chemistry and ozone production: Results from SHARP 2009 in Houston, Texas [PDF]

, 2014
This study considers whether spikes in nitrate in snow sampled at Summit, Greenland, from August 2000 to August 2002 are related to solar proton events. After identifying tropospheric sources of nitrate on the basis of correlations with sulfate, ammonium,
Dibb, Jack E., Duderstadt, Katherine A., Jackman, Charles H., Mills, Michael J., Randall, Cora E., Schwadron, Nathan A., Solomon, Stanley C., Spence, Harlan E.   +7 more
core   +1 more source

Dentrification potential of different landuse types in an agricultural watershed, lower Mississippi valley. [PDF]

, 2006
Expansion of agricultural land and excessive nitrogen (N) fertilizer use in the Mississippi River watershed has resulted in a three-fold increase in the nitrate load of the river since the early 1950s.
Faulkner, Stephen, Ullah, Sami
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Simultaneous Determination of Nitrite and Nitrate in Milk Samples by Ion Chromatography Method and Estimation of Dietary Intake [PDF]

, 2016
The presence of nitrate and nitrite in foods may be considered hazardous after ingestion in the gastrointestinal tract due to their reaction with naturally occurred secondary amines to form potentially carcinogenic nitrosamines.
Chamandust, S., Hosseini, M.-J., Kamali, K., Mehrasebi, M.R., Nazari, F., Solgi, R., Taran, J.   +6 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

DL-Asparaginium nitrate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
En el compuesto del título,C4H9N2O3 +·NO3−, alternativamente llamado nitrato de (1RS) -2-carbamoil-1-carboxietanaminio, la unidad asimétrica comprende un catión asparaginio y un anión nitrato. El enlace de hidrógeno O—HO catiónico más fuerte en la estructura, junto con otros enlaces de hidrógeno N—HO catiónicos fuertes, genera una sucesión de cadenas ...
Nabila Moussa Slimane, Aouatef Cherouana, Lamia Bendjeddou, Slimane Dahaoui, Claude Lecomte   +4 more
openaire   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source