Results 81 to 90 of about 865,702 (313)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Regression-based machine learning models for nitrate and chloride prediction in surface water in a small agricultural sand plain sub-watershed in southwestern Ontario, Canada

Frontiers in Environmental Science
Machine learning (ML) models have proven to be an efficient technique for better understanding and quantification of surface water quality, especially in agricultural watersheds where considerable anthropogenic activities occur.
Ahmed Elsayed, Ahmed Elsayed, Jana Levison, Andrew Binns, Marie Larocque, Pradeep Goel   +5 more
doaj   +1 more source

Atmospheric oxidation chemistry and ozone production: Results from SHARP 2009 in Houston, Texas [PDF]

, 2014
This study considers whether spikes in nitrate in snow sampled at Summit, Greenland, from August 2000 to August 2002 are related to solar proton events. After identifying tropospheric sources of nitrate on the basis of correlations with sulfate, ammonium,
Dibb, Jack E., Duderstadt, Katherine A., Jackman, Charles H., Mills, Michael J., Randall, Cora E., Schwadron, Nathan A., Solomon, Stanley C., Spence, Harlan E.   +7 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Homogenous catalysis of peroxynitrite conversion to nitrate by diaryl selenide: a theoretical investigation of the reaction mechanism

Frontiers in Chemistry
Quenching peroxynitrite (a reactive oxidant species) is a vital process in biological systems and environmental chemistry as it maintains redox balance and mitigates damaging effects in living cells and the environment.
Yuan Xue, Yuan Xue, Carrie Salmon, Valentin Gogonea, Valentin Gogonea, Valentin Gogonea   +5 more
doaj   +1 more source

Isotope tracing of nitrate : lessons from Malta [PDF]

, 2010
Average concentrations of nitrate in Malta’s groundwaters are probably the highest among EU member states. This compromises the quality of an important resource -almost 60% of Malta’s water supply being provided by groundwater.
Heaton, Timothy, Micallef Sultana, M., Sapiano, M., Stuart, Marianne   +3 more
core  

The influence of nitrate leaching through unsaturated soil on groundwater pollution in an agricultural area of the Basque country: a case study [PDF]

, 2003
The average nitrate concentration in the groundwater of the Vitoria-Gasteiz (Basque Country) quaternary aquifer rose from 50 mg NO3−/l during 1986 to over 200 mg/l in 1995, which represents an increase of some 20 mg NO3−/l per year.
Antigüedad, Iñaki, Arrate, Iñaki, García-Linares, Cristina, Morell, Ignacio, Sanchez-Pérez, José-Miguel   +4 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Five-Day Supplementation with an Isotonic Beetroot Juice Drink Improves Sprint Interval Exercise and Muscle Oxygenation in Physically Active Individuals: A Randomized Crossover Trial

Beverages
This study investigated whether the addition of nitrate (from beetroot) to an isotonic drink provided over 5 days would affect sprint interval exercise (SIE) performance and muscle oxygenation. Twenty (seven female) physically active participants (mean ±
Tak Hiong Wong, Delicia Shu Qin Ooi, Stephen F. Burns   +2 more
doaj   +1 more source

Nitrate-Induced CLE Peptide Systemically Inhibits Nodulation in Medicago truncatula

Plants, 2020
Legume plants form nitrogen-fixing nodules in symbiosis with soil bacteria rhizobia. The number of symbiotic nodules is controlled at the whole-plant level with autoregulation of nodulation (AON), which includes a shoot-acting CLV1-like receptor kinase ...
Maria Lebedeva, Mahboobeh Azarakhsh, Yaroslavna Yashenkova, Lyudmila Lutova   +3 more
doaj   +1 more source