Results 71 to 80 of about 1,236,345 (391)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Subsurface biogeochemical cycling of nitrogen in the actively serpentinizing Samail Ophiolite, Oman

open access: yesFrontiers in Microbiology, 2023
Nitrogen (N) is an essential element for life. N compounds such as ammonium (NH4+) may act as electron donors, while nitrate (NO3-) and nitrite (NO2-) may serve as electron acceptors to support energy metabolism.
Kaitlin R. Rempfert   +9 more
doaj   +1 more source

The interpretation of spikes and trends in concentration of nitrate in polar ice cores, based on evidence from snow and atmospheric measurements [PDF]

open access: yes, 2008
Nitrate is frequently measured in ice cores, but its interpretation remains immature. Using daily snow surface concentrations of nitrate at Halley (Antarctica) for 2004 - 2005, we show that sharp spikes (> factor 2) in nitrate concentration can occur ...
Bauguitte, S.J.-B.   +3 more
core   +3 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Nitrate quantification: recent insights into enzyme-based methods

open access: yesReviews in Analytical Chemistry, 2016
Nitrate monitoring of environmental samples is essential to safeguard human and environmental health. Various non-enzymatic methods such as Griess reaction-based chemical method; Fourier transform infrared spectroscopy; chromatographic, electrochemical ...
Hooda Vinita   +2 more
doaj   +1 more source

Digestate is equal or a better alternative to mineral fertilization of kohlrabi

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2012
In a one-year vegetation pot experiment, we compared the effect of digestate from a biogas station and mineral fertilisers on yield and quality parameters of kohlrabi, variety Segura F1.
Tomáš Lošák   +9 more
doaj   +1 more source

Global perspective of nitrate flux in ice cores [PDF]

open access: yes, 1995
The relationships between the concentration and the flux of chemical species (Cl-, NO3 - , SO42-, Na +, K + , NH4 + , Mg 2+ , Ca 2+) versus snow accumulation rate were examined at GISP2 and 20D in Greenland, Mount Logan from the St.
Dibb, Jack E.   +7 more
core   +3 more sources

Solubility-mediated sustained release enabling nitrate additive in carbonate electrolytes for stable lithium metal anode

open access: yesNature Communications, 2018
The physiochemical properties of the solid-electrolyte interphase, primarily governed by electrolyte composition, have a profound impact on the electrochemical cycling of metallic lithium.
Yayuan Liu   +7 more
semanticscholar   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Is nitrate a good biomarker of the nitric oxide status? / Este ionul nitrat un bun biomarker al producţiei endogene de monoxid de azot?

open access: yesRomanian Journal of Laboratory Medicine, 2015
Determinarea concentraţiilor in vivo ale monoxidului de azot (NO) este necesară pentru identificarea condiţiilor patologice în care producţia endogenă a acestui compus este redusă sau pentru identificarea unor agenţi care pot genera in vivo acest compus.
Croitoru Mircea Dumitru   +3 more
doaj   +1 more source

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