Results 171 to 180 of about 36,622 (311)

Physiological Studies on Nodule-Nitrate Reductase [PDF]

, 1960
George M. Cheniae, Harold J. Evans
openalex   +1 more source

Isoniazid‐Dihydropyrimidinone Molecular Hybrids: Design, Synthesis, Antitubercular Activity, and Cytotoxicity Investigations with Computational Validation

ChemMedChem, EarlyView.
Antitubercular evaluation of a novel library of isoniazid‐dihydropyrimidinone molecular hybrids (8a–8n) discloses a potent compound with MIC = 0.39μg mL−1 against M. tuberculosis mc26230. Cytotoxicity, stability, and in silico studies, including molecular docking and ADME/T (absorption, distribution, metabolism, excretion, and toxicity) analysis ...
Gobind Kumar, Pule Seboletswe, Sahil Mishra, Neha Manhas, Safiyah Ghumran, Nagaraju Kerru, Françoise Roquet‐Banères, Maëlle Foubert, Laurent Kremer, Gaurav Bhargava, Parvesh Singh   +10 more
wiley   +1 more source

Comparison of in Vivo and in Vitro Assays of Nitrate Reductase in Wheat (Triticum aestivum L.) Seedlings [PDF]

, 1976
Nichola Brunetti, Richard H. Hageman
openalex   +1 more source

Systematic Review on 1,2,3‐Oxadiazoles, 1,2,4‐Oxadiazoles, and 1,2,5‐Oxadiazoles in the Antimycobacterial Drug Discovery

ChemMedChem, EarlyView.
The review focuses on relationships of oxadiazole derivative structures and their antimycobacterial activity including target structures in mycobacteria, in vitro or in vivo pharmacokinetic parameters, and toxicity. Apart from direct antimycobacterial activity, some 1,2,4‐oxadiazole derivatives can potentiate the antimycobacterial effect of ethionamide
Marta Kučerová‐Chlupáčová
wiley   +1 more source

Comparative Studies on the Induction and Inactivation of Nitrate Reductase in Corn Roots and Leaves [PDF]

, 1976
Muhammad Aslam, Ann Oaks
openalex   +1 more source

Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites

ChemMedChem, EarlyView.
Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert, Lucie Paloque, Jean‐Michel Augereau, Flore Nardella, Michel Nguyen, Bernard Meunier, Françoise Benoit‐Vical   +6 more
wiley   +1 more source

Effect of Light and Glucose on the Induction of Nitrate Reductase and on the Distribution of Nitrate in Etiolated Barley Leaves [PDF]

, 1976
Muhammad Aslam, Ann Oaks, Ray C. Huffaker   +2 more
openalex   +1 more source

Novel quinazolinones active against multidrug‐resistant Mycobacterium tuberculosis: synthesis, antimicrobial evaluation and in silico exploration of PonA1 as a potential target

ChemMedChem, Accepted Article.
Quinazolinone derivatives have emerged as promising scaffolds in antimicrobial drug discovery. This work focuses on the design, synthesis, and evaluation of novel quinazolinone‐based compounds and predicts their potential to interact with mycobacterial penicillin‐binding proteins (PBPs).
MAREK KERDA, Daria Nawrot, Petr Slechta, Mirek Domanský, Asal Askari, Hanieh Kamangar, Ondřej Janďourek, Klára Konečná, Pavla Paterová, Ingrid Hlbočanová, Miloslav Macháček, Matteo Mori, Fiorella Meneghetti, Martin Doležal, Jan Zitko, Ghada Bouz   +15 more
wiley   +1 more source

Inorganic Metal Nanoparticles in Reproductive Biology: Applications, Toxicities and Future Prospects

ChemPlusChem, EarlyView.
Metal nanoparticles (MNPs) have shown great promise in the livestock industry such as semen collection, nano‐purification, cryopreservation, sex sorting, bioimaging, drug and gene delivery. However, reproductive toxicity induced by MNP has adverse effects on various sexual functions including poor sperm parameters, testicular damage, ovary injury, and ...
Sangita Kundu, Wilfried A. Kues, Christoph Rehbock, Stephan Barcikowski   +3 more
wiley   +1 more source

Control of Nitrate Reductase Activity in Barley Aleurone Layers [PDF]

, 1970
Thomas E. Ferrari, Joseph E. Varner
openalex   +1 more source