Results 61 to 70 of about 579,869 (390)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The dependence of nitrate reductase activity on the level of soluble sugars in wheat and cucumber roots growing in the presence of simazine, in light or in darkness

Acta Societatis Botanicorum Poloniae, 2014
At concentrations of 25 and 5 µM, simazine inhibited nitrate reductase activity in wheat and cucumber roots, respectively. It also lowered the content of soluble sugars and decreased the activities of NADH malate dehydrogenase and NADP+ glucose-6 ...
Józef Buczek, Jacek Borkowski, Irena Jarzyńska   +2 more
doaj   +1 more source

Arabidopsis Growth-Promotion and Root Architecture Responses to the Beneficial Rhizobacterium Phyllobacterium brassicacearum Strain STM196 Are Independent of the Nitrate Assimilatory Pathway

Plants, 2022
Phyllobacterium brassicacearum STM196, a plant growth-promoting rhizobacterium isolated from roots of oilseed rape, stimulates Arabidopsis growth. We have previously shown that the NRT2.5 and NRT2.6 genes are required for this growth promotion response ...
Maya Kechid, Guilhem Desbrosses, Lydia Gamet, Loren Castaings, Fabrice Varoquaux, Abdelhamid Djekoun, Bruno Touraine   +6 more
doaj   +1 more source

Potassium Nitrate Priming Affects the Activity of Nitrate Reductase and Antioxidant Enzymes in Tomato Germination

, 2014
Priming has been used to improve the performance of germination at the field, and potassium nitrate (KNO 3 ) is a promising compound for this purpose. The nitrate (NO 3 ) could be absorbed, being used in the metabolism of the embryo, through the enzyme ...
T. S. Lara, J. Lira, A. C. Rodrigues, M. Rakočević, A. A. Alvarenga   +4 more
semanticscholar   +1 more source

Arabidopsis nitrate reductase activity is stimulated by the E3 SUMO ligase AtSIZ1

Nature Communications, 2011
Small ubiquitin-related modifier (SUMO) is a small polypeptide that modulates protein activity and regulates hormone signalling, abiotic and biotic responses in plants. Here we show that AtSIZ regulates nitrogen assimilation in Arabidopsis through its E3
B. Park, J. Song, H. Seo
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Physiological and genetic description of dissimilatory perchlorate reduction by the novel marine bacterium Arcobacter sp. strain CAB. [PDF]

, 2013
A novel dissimilatory perchlorate-reducing bacterium (DPRB), Arcobacter sp. strain CAB, was isolated from a marina in Berkeley, CA. Phylogenetically, this halophile was most closely related to Arcobacter defluvii strain SW30-2 and Arcobacter ellisii ...
Bauer, Stefan, Carlström, Charlotte, COATES, John, Engelbrektson, Anna, Lee, Joyce, Melnyk, Ryan, Wang, Ouwei   +6 more
core   +2 more sources

Protein Phosphatase 2A B55 and A Regulatory Subunits Interact with Nitrate Reductase and Are Essential for Nitrate Reductase Activation1[W][OA]

Plant Physiology, 2011
Posttranslational activation of nitrate reductase (NR) in Arabidopsis (Arabidopsis thaliana) and other higher plants is mediated by dephosphorylation at a specific Ser residue in the hinge between the molybdenum cofactor and heme-binding domains.
Behzad Heidari, Polina R Matre, Dugassa Nemie-Feyissa, C. Meyer, O. Rognli, S. Møller, C. Lillo   +6 more
semanticscholar   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Sulfide- and nitrite-dependent nitric oxide production in the intestinal tract [PDF]

, 2011
In the gut ecosystem, nitric oxide (NO) has been described to have damaging effects on the energy metabolism of colonocytes. Described mechanisms of NO production are microbial reduction of nitrate via nitrite to NO and conversion of l-arginine by NO ...
Boeckx, Pascal, Boon, Nico, Van de Wiele, Tom, Van Nieuwenhuyse, Glynn, Vermeiren, Joan, Verstraete, Willy   +5 more
core   +1 more source