Results 101 to 110 of about 149,344 (340)
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy+14 more
wiley +1 more source
Nucleation kinetics in drying sodium nitrate aerosols [PDF]
A quantitative understanding of the evaporative drying kinetics and nucleation rates of aqueous based aerosol droplets is important for a wide range of applications, from atmospheric aerosols to industrial processes such as spray drying. Here, we introduce a numerical model for interpreting measurements of the evaporation rate and phase change of ...
arxiv
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang+7 more
wiley +1 more source
Nitrate reduction in the rumen of the grazing sheep [PDF]
N. D. Jamieson
openalex +1 more source
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria
The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao+4 more
wiley +1 more source
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu+4 more
wiley +1 more source
The influence of irrigation on nitrates movement in soil and risk of subsoil contamination
This paper presents the results of the nitrates movement monitoring under the conditions of field experiment, with different fertilisation doses applications, with and without irrigation and, for different crops.
Katarína NOVÁKOVÁ, Dušan NÁGEL
doaj +1 more source
Abstract Introduction The use of radioactive materials in the United States has been tightly regulated by the Nuclear Regulatory Commission and other entities for many decades. In 2015, however, the Joint Commission began to require hospital‐based nuclear medicine departments to conduct shielding designs and evaluations for radioactive material areas ...
Michael Oumano+12 more
wiley +1 more source