Results 101 to 110 of about 265,215 (357)

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Possible Detection of Nitrates on Mars by the Sample Analysis at Mars (SAM) Instrument [PDF]

, 2013
Planetary models suggest that nitrogen was abundant in the early Martian atmosphere as dinitrogen (N2). However, it has been lost by sputtering and photochemical loss to space [1, 2], impact erosion [3], and chemical oxidation to nitrates [4].
Archer, D., Atreya, S., Brunner, A. E., Buch, A., Cabane, M., Coll, P., Conrad, P., Eigenbrode, J. L., Franz, H. B., Freissinet, C., Glavin, D., Jones, J. H., Leshin, L., Mahaffy, P., McAdam, A., McKay, C. P., Ming, D. W., Navarro-Gonzalez, R., Prats, B. D., Steele, A., Stern, J., Sutter, B., Szopa, C., Wong, M., Wray, J. J.   +24 more
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Investigation of the reactivity of AlCl3 and CoCl2 toward molten alkali-metal nitrates in order to synthesize CoAl2O4 [PDF]

, 2004
Cobalt aluminate CoAl2O4 powder, constituted of nano-sized crystallites, is prepared, involving the reactivity of AlCl3 and CoCl2 with molten alkali-metal nitrates.
A. Samdi, Aboujalil, B. Durand, Baraton, Bernardi, Bolt, Bondioli, Buxbaum, Chemlal, Chen, Cho, Chokkram, Descemond, Durand, Durand, Eric-Antonic, Frouzanfar, Gadsden Aric, Hamon, Harle, J.J. Demai, Ji, Kerridge, Kerridge, Kulikova, L. Er Rakho, Lakhlifi, Lux, Melo, Merikhi, Meyer, N. Ouahdi, Otero Areán, R. Moussa, S. Guillemet, Singh, Strangar, Topol   +37 more
core   +1 more source

Forskolin Enhances Urokinase Plasminogen Activator Secretion and Angiogenic Activity of Xeno‐Free Cultures of Human Adipose Tissue‐Derived Stem Cells

Advanced Biology, EarlyView.
The regenerative potential of adipose tissue‐derived stem cells can be enhanced through chemical stimulation in vitro. A short stimulation protocol using forskolin, either alone or in combination with other growth factors, under xeno‐free conditions enhanced the pro‐angiogenic responses in human ASCs.
Maria Vittoria Giraudo, Anne Therese Lauvrud, Rebecca Wiberg, Maria Brohlin, Gustav Andersson, Paul J Kingham   +5 more
wiley   +1 more source

Estimating the Self-depuration Capacity of a Reach of the Luján River [PDF]

, 2015
A 3-km reach of the Luján River was studied by establishing 6 sampling stations, which were from 300 to 500 m apart. The first station was the control reading for river nutrients and particulate material.
Giorgi, Adonis David Nazareno, Gultermiriam, M.L., Piccinini, Mauricio, Sánchez Caro, Anibal   +3 more
core   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Antarctic polar stratospheric aerosols: The roles of nitrates, chlorides and sulfates [PDF]

Nitric and hydrochloric acids have been postulated to condense in the winter polar stratosphere to become an important component of polar stratospheric clouds.
Ferry, G. V., Fong, W., Goodman, J. K., Oberbeck, V. R., Pueschel, R. F., Snetsinger, K. G., Verma, S.   +6 more
core   +1 more source

Gearing of nitrate ions in ammonium nitrate

The Journal of Chemical Physics
Reorienting polyatomic ions such as NH4+ and NO3− exhibit weak magnetic fields because the ions at the extremities trace out current loops; if the periodic reorientations become long-range ordered (i.e., gearing of neighboring NO3−), then the magnetic susceptibility should exhibit a unique signature along the different crystallographic axes.
Na Du, Xintian Wang, Yu Ying Zhu, Chanreingam Long, Peng Ren, Fei Yen   +5 more
openaire   +2 more sources