Results 111 to 120 of about 265,215 (357)
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li+10 more
wiley +1 more source
Nitrates in the treatment of patients with coronary artery disease. The role of aerosol formulations
Nitrates have been commonly used in the treatment of patients with cardiovascular disease (CVD) for about 150 years. However, the feasibility and safety of nitrates in cardiology remains a matter of debate till today. Among CVDs, coronary artery disease (
AG Evdokimova, VV Evdokimov, NA Kozhina
doaj +1 more source
On the occurrence of degenerative changes in the liver in animals intoxicated by mercuric chloride and by uranium nitrate. [PDF]
William deB. MacNider
openalex +1 more source
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen+4 more
wiley +1 more source
For many years, coronary heart disease (CHD) has been the main cause of death in many developed countries. At present, cardiovascular diseases (CVD) play a crucial role in the evolution of total mortality in Russia.
MV Kuznetsova
doaj +1 more source
AISI 304L stainless steel powder is mixed with silicon nitride (Si3N4) powder and processed by PBF‐LB/M, allowing partial retention of Si3N4. The numerical approach effectively predicts the Si3N4 powder homogeneity and N content distribution on the powder bed. Recent studies have focused on the alloying of nitrogen (N) in high‐alloy stainless steels by
Yuanbin Deng+7 more
wiley +1 more source
Impact of cattle stocking rate, under grazing, during autumn on potential nitrogen leaching: reference values established in the south-east of Belgium.
Hennart, S., Lambert, A., Stilmant, D.
doaj
Farm-gate N and P balances and use efficiencies across specialist dairy farms in the Republic Ireland [PDF]
working paperThis study establishes farm gate N and P balances and use efficiencies based on the average of 2 years of Teagasc National Farm Survey data in 2009 and 2010.
Buckley, Cathal+2 more
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