Results 111 to 120 of about 265,215 (357)

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

open access: yesAdvanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li   +10 more
wiley   +1 more source

Nitrates in the treatment of patients with coronary artery disease. The role of aerosol formulations

open access: yesМедицинский совет, 2014
Nitrates have been commonly used in the treatment of patients with cardiovascular disease (CVD) for about 150 years. However, the feasibility and safety of nitrates in cardiology remains a matter of debate till today. Among CVDs, coronary artery disease (
AG Evdokimova, VV Evdokimov, NA Kozhina
doaj   +1 more source

Nitrate of Pilocarpine [PDF]

open access: yesThe Boston Medical and Surgical Journal, 1877
n ...
openaire   +2 more sources

Modelling Atherosclerotic Plaque Cap Mechanics: Microcalcifications Reduce Mechanical Properties in Mesenchymal Stromal Cell‐Based Model

open access: yesAdvanced Biology, EarlyView.
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen   +4 more
wiley   +1 more source

Pain in angina attack

open access: yesМедицинский совет, 2014
For many years, coronary heart disease (CHD) has been the main cause of death in many developed countries. At present, cardiovascular diseases (CVD) play a crucial role in the evolution of total mortality in Russia.
MV Kuznetsova
doaj   +1 more source

Numerical Studies of Influencing Factors on the Homogeneity of the Powder Mixture during the Powder Spreading Process of Powder Bed Fusion–Laser Beam/Metal

open access: yesAdvanced Engineering Materials, Volume 27, Issue 14, July 2025.
AISI 304L stainless steel powder is mixed with silicon nitride (Si3N4) powder and processed by PBF‐LB/M, allowing partial retention of Si3N4. The numerical approach effectively predicts the Si3N4 powder homogeneity and N content distribution on the powder bed. Recent studies have focused on the alloying of nitrogen (N) in high‐alloy stainless steels by
Yuanbin Deng   +7 more
wiley   +1 more source

Impact du chargement d'arrière-saison sur les teneurs en azote potentiellement lessivable en prairie : références établies dans le sud-est de la Belgique

open access: yesBiotechnologie, Agronomie, Société et Environnement, 2013
Impact of cattle stocking rate, under grazing, during autumn on potential nitrogen leaching: reference values established in the south-east of Belgium.
Hennart, S., Lambert, A., Stilmant, D.
doaj  

Farm-gate N and P balances and use efficiencies across specialist dairy farms in the Republic Ireland [PDF]

open access: yes, 2013
working paperThis study establishes farm gate N and P balances and use efficiencies based on the average of 2 years of Teagasc National Farm Survey data in 2009 and 2010.
Buckley, Cathal   +2 more
core  

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