Results 61 to 70 of about 598,249 (382)
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
FEBS Letters, EarlyView.The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
Earth, 2023 Protecting groundwater from contamination is today’s most current environmental protection topic. What can man do in his environment to reduce the harmful impact of contamination on the environment, and thus the immediate effect on groundwater ...
Marko Šrajbek +3 more
doaj +1 more source
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2013 In 2010 and 2011 two experiments on gimmers of Šumava mountain sheep were performed. The first experiment was carried out on 12 animals (experimental period was 11 months); control group was fed with 3 mg I*kg−1 in dry matter per day and experimental ...
Zdeněk Peksa +9 more
doaj +1 more source
Nitrates, Nitrites and Nitrosamines from Processed Meat Intake and ColorectalCancer Risk
, 2017 The International Agency for Research on Cancer reported that eating processed meat can increase a person’s risk for colorectal cancer and classified processed meat as carcinogenic to humans.
M. Cantwell, C. Elliott
semanticscholar +1 more source
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
The influence of irrigation on nitrates movement in soil and risk of subsoil contamination
Soil and Water Research, 2009 This paper presents the results of the nitrates movement monitoring under the conditions of field experiment, with different fertilisation doses applications, with and without irrigation and, for different crops.
Katarína NOVÁKOVÁ, Dušan NÁGEL
doaj +1 more source
Observations of total RONO2 over the boreal forest: NO x sinks and HNO3 sources [PDF]
, 2013 In contrast with the textbook view of remote chemistry where HNO 3 formation is the primary sink of nitrogen oxides, recent theoretical analyses show that formation of RONO2 (ΣANs) from isoprene and other terpene precursors is the primary net chemical ...
Apel, E +13 more
core +1 more source
WETWALL - an innovative design concept for the treatment of wastewater at an urban scale [PDF]
, 2018 Rising temperatures, increasing food demand and scarcity of water and land resources highlight the importance of promoting the sustainable expansion of agriculture to our urban environment, while preserving water resources.
Arias, Carlos Alberto +7 more
core +4 more sources
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source