Results 71 to 80 of about 165,176 (291)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Impact of Vermicompost as Component of Growing Medium on Phytomass Formation of Radish (Raphanus Sativus L.)

Agriculture, 2018
In Slovakia more than a half of the landfill‘s waste consist of the biodegradable waste (BDW). Therefore the BDW composting can decrease significantly the production of the landfill gas as well as the financial and space requirements for landfills ...
Kováčik Peter, Šalamun Peter, Smoleń Sylwester, Renčo Marek   +3 more
doaj   +1 more source

Increase in the biomass of some green algae species in nitrate and ammonium mediums depending on auto-, mixo- or heterotrophic conditions

Acta Societatis Botanicorum Poloniae, 2014
The increase in total dry mass and protein in cultures of Chlorella pyrenoidosa, Scenedesmus quadricauda and Ankistrodesmus acicularis was studied. Under autotrophic conditions, increases in dry mass were, as a rule, larger in the nitrate medium than in ...
Stefan Gumiński, Krystyna Jurajda, Ewa Tatkowska   +2 more
doaj   +1 more source

DL-Asparaginium nitrate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
En el compuesto del título,C4H9N2O3 +·NO3−, alternativamente llamado nitrato de (1RS) -2-carbamoil-1-carboxietanaminio, la unidad asimétrica comprende un catión asparaginio y un anión nitrato. El enlace de hidrógeno O—HO catiónico más fuerte en la estructura, junto con otros enlaces de hidrógeno N—HO catiónicos fuertes, genera una sucesión de cadenas ...
Nabila Moussa Slimane, Aouatef Cherouana, Lamia Bendjeddou, Slimane Dahaoui, Claude Lecomte   +4 more
openaire   +3 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Beetroot Juice as a Natural Ergogenic Supplement: A Literature Review of Its Effects on Physical Performance and Training Adaptation

Quality in Sport
Purpose: This study aims to review the current literature on the effects of beetroot juice supplementation on physical performance, training adaptation, and safety.
Julia Głowacz, Michal Popiel, Kamil Dziekoński, Jakub Rybowski, Sylwia Krzyśkowska, Aneta Redner, Iga Kwiecień, Patrycja Zwierzchlewska, Bartosz Rusin, Dominik Stanibuła, Kacper Buczek   +10 more
doaj   +1 more source

2,4,6-Trimethylpyridinium nitrate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2010
في مركب العنوان، C(8)H(12)N (+) ·NO(3) (-)، يقع الكاتيون على مستوى مرآة وتقع ذرة N و C واحدة على محور مزدوج. في البلورة، ترتبط الأنيونات والكاتيونات بتفاعلات N - HO على طول المحور b ويحدث أيضًا اتصال قصير n - o OP [3.2899 (5) Å].
Shahzad Sharif, Mehmet Akkurt, Islam Ullah Khan, Abdur Rauf, Irfana Mariam   +4 more
openaire   +4 more sources

Manure Incorporation and Reduced Tillage Corn Trial [PDF]

, 2015
Timely manure incorporation can reduce nutrient losses to the atmosphere and surface runoff. Keeping valuable nutrients, like nitrogen, in the soil can help reduce the purchase of expensive commercial fertilizers.
Calderwood, Lily, Cubins, Julija, Cummings, Erica, Darby, Heather, Gupta, Abha, Post, Julian, Ziegler, Sara   +6 more
core   +1 more source