Results 71 to 80 of about 265,215 (357)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Ocena zawartości azotanów w wodach rzeki Dunajec

open access: yesAgronomy Science, 2006
Human activities transform the natural environment and cause an extreme biogen inflow to surface waters. The current investigation was aimed to estimate the effect of agricultural and domestic human activities at lowland area of the Dunajec watershed on ...
Barbara Wiśniowska-Kielian   +1 more
doaj  

Presence of nitrates in baby foods marketed in Portugal

open access: yesCogent Food & Agriculture, 2015
This study was carried out to determine the current levels of nitrates in baby foods marketed in Lisbon, Portugal to estimate the toxicological risk associated with their intake. The nitrate content was determined in bottled baby foods of four varieties:
João Sebastião Rebelo   +3 more
doaj   +1 more source

Nitrites, Nitrates, and Cardiovascular Outcomes: Are We Living “La Vie en Rose” With Pink Processed Meats?

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Nitrates and nitrites are used as food additives in processed meats. They are also commonly ingested from water and several foods. Several short‐term clinical studies suggested beneficial effects of dietary nitrates on blood pressure, while ...
Bernard Srour   +9 more
doaj   +1 more source

Selection of medication in hospitalised elderly patients with Angina Pectoris [PDF]

open access: yes, 2004
Objective: To evaluate medication changes in hospitalised elderly patients diagnosed with angina pectoris and to compare the selection of medication with evidence-based treatment guidelines. Design: Review of medical notes and patient interview. Setting:
Cacciottolo, Joseph M.   +2 more
core  

Impact of nitrogen fertilizers on the natural weathering-erosion processes and fluvial transport in the Garonne basin [PDF]

open access: yes, 2000
Knowledge of the impact of N-fertilizers on the weathering-erosion processes of soils in intensively cultivated regions is of prime importance. Nitrification of NH4− fertilizers produces HNO3 in the basin of the Garonne river, enhancing soil degradation.
Amiotte Suchet, Philippe   +3 more
core   +2 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Effect of biostimulant raw materials on soybean (Glycine max) crop, when applied alone or in combination with herbicides

open access: yesFrontiers in Agronomy, 2023
IntroductionBiostimulants exert positive functions in plants, improving yield and quality, and alleviating the negative effects of abiotic stresses. Among them, the application of herbicides may cause damage to nontarget plants.
Giulia Franzoni   +6 more
doaj   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

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