Results 81 to 90 of about 165,485 (291)

2,4,6-Trimethylpyridinium nitrate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2010
في مركب العنوان، C(8)H(12)N (+) ·NO(3) (-)، يقع الكاتيون على مستوى مرآة وتقع ذرة N و C واحدة على محور مزدوج. في البلورة، ترتبط الأنيونات والكاتيونات بتفاعلات N - HO على طول المحور b ويحدث أيضًا اتصال قصير n - o OP [3.2899 (5) Å].
Shahzad Sharif, Mehmet Akkurt, Islam Ullah Khan, Abdur Rauf, Irfana Mariam   +4 more
openaire   +4 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Nitrate-Dependent Iron Oxidation: A Potential Mars Metabolism [PDF]

, 2018
This work considers the hypothetical viability of microbial nitrate-dependent Fe2+ oxidation (NDFO) for supporting simple life in the context of the early Mars environment.
Abramov, Amils, Anand, Arevalo, Arnold, Arvidson, Bauermeister, Benz, Bibring, Bridges, Bridges, Bruce, Busigny, Byrne-Bailey, Cabrol, Canfield, Carlson, Carlson, Carr, Chakraborty, Chakraborty, Changela, Charlou, Chassefière, Chastain, Chaudhuri, Chevrier, Cockell, Cockell, Cockell, Comeau, Czaja, Dartnell, Edwards, Edwards, Edwards, Ehlmann, Ehlmann, Ehlmann, Ehrenreich, Emerson, Emerson, Emerson, Etique, Ettwig, Fassett, Filiberto, Fisk, Formisano, Fowler, Fox, Fox, Fox-Powell, Frydenvang, Gauger, Gendrin, Glavin, Grady, Gronstal, Grotzinger, Grotzinger, Hafenbradl, Hecht, Hedrich, Hicks, Hoefen, Hoehler, Hoppert, Hurowitz, Ilbert, Ionescu, Irwin, Jakosky, Jepsen, Johnson, Kappler, Kappler, Kappler, King, Kish, Klueglein, Klueglein, Konhauser, Konn, Kounaves, Kumaraswamy, Lack, Lalonde, Lanza, Laufer, Lopez-Reyes, Lovley, Lovley, Madigan, Mahaffy, Malin, Mangold, Manning, Martin, Martín-Torres, Marzo, McSween, McSween, Michalski, Millero, Ming, Ming, Miot, Miot, Miot, Miot, Miot, Miot, Miot, Miot, Mirvaux, Montoya, Morgan, Morris, Morris, Morris, Muehe, Myers, Nachon, Navarro-González, Nealson, Nie, Nixon, Nixon, Nixon, Oren, Osinski, Palucis, Pantke, Parnell, Pirajno, Popa, Raghoebarsing, Raiswell, Ramirez, Rampe, Rampe, Reimers, Revsbech, Roden, Santelli, Schieber, Schuerger, Schwenzer, Schwenzer, Schädler, Sephton, Sholes, Smith, Smith, Squyres, Squyres, Squyres, Steele, Stern, Stern, Stevens, Straub, Straub, Straub, Strohm, Summers, Summers, Summers, Sutter, Toporski, Tosca, Tosca, Tuff, Vaniman, Visscher, Wacey, Weber, Weber, Weber, Webster, Welhan, Wheat, Williams, Yen, Yen   +185 more
core   +4 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Quantifying the impact of BOReal forest fires on Tropospheric oxidants over the Atlantic using Aircraft and Satellites (BORTAS) experiment: design, execution and science overview [PDF]

, 2013
We describe the design and execution of the BORTAS (Quantifying the impact of BOReal forest fires on Tropospheric oxidants over the Atlantic using Aircraft and Satellites) experiment, which has the overarching objective of understanding the chemical ...
Andrews, S., Aruffo, E., Bailey, L. J., Barrett, E., Bauguitte, S. J.-b., Bernath, P. F., Chisholm, L., Curry, K. R., Da Silva, A. M., Dan, L., Di Carlo, P., Duck, T. J., Forster, G., Franklin, J. E., Gibson, M. D., Griffin, D., Helmig, D., Hopkins, J. R., Hopper, J. T., Jenkin, M. E., Kindred, D., Kliever, J., Le Breton, M., Lee, J. D., Lewis, A. C., Matthiesen, S., Maurice, M., Moller, S., Moore, D. P., O'shea, S. J., Oram, D. E., Owen, R. C., Pagniello, C. M. L. S., Palmer, P. I., Parrington, M., Pawson, S., Percival, C. J., Pierce, J. R., Punjabi, S., Purvis, R. M., Remedios, J. J., Rickard, A. R., Rotermund, K. M., Sakamoto, K. M., Strawbridge, K. B., Strong, K., Tarasick, D. W., Taylor, J., Tereszchuk, K. A., Trigwell, R., Walker, K. A., Waugh, D. L., Weaver, D., Whaley, C., Young, J. C.   +54 more
core   +2 more sources

Aminoethyl nitrate – the novel super nitrate? [PDF]

British Journal of Pharmacology, 2009
Long‐term use of most organic nitrates is limited by development of tolerance, induction of oxidative stress and endothelial dysfunction. In this issue of the BJP, Schuhmacher et al. characterized a novel class of organic nitrates with amino moieties (aminoalkyl nitrates).
openaire   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Impact du chargement d'arrière-saison sur les teneurs en azote potentiellement lessivable en prairie : références établies dans le sud-est de la Belgique

Biotechnologie, Agronomie, Société et Environnement, 2013
Impact of cattle stocking rate, under grazing, during autumn on potential nitrogen leaching: reference values established in the south-east of Belgium.
Hennart, S., Lambert, A., Stilmant, D.
doaj  

Nitrates in the treatment of patients with coronary artery disease. The role of aerosol formulations

Медицинский совет, 2014
Nitrates have been commonly used in the treatment of patients with cardiovascular disease (CVD) for about 150 years. However, the feasibility and safety of nitrates in cardiology remains a matter of debate till today. Among CVDs, coronary artery disease (
AG Evdokimova, VV Evdokimov, NA Kozhina
doaj   +1 more source

Manure Incorporation and Reduced Tillage Corn Trial [PDF]

, 2015
Timely manure incorporation can reduce nutrient losses to the atmosphere and surface runoff. Keeping valuable nutrients, like nitrogen, in the soil can help reduce the purchase of expensive commercial fertilizers.
Calderwood, Lily, Cubins, Julija, Cummings, Erica, Darby, Heather, Gupta, Abha, Post, Julian, Ziegler, Sara   +6 more
core   +1 more source