Results 81 to 90 of about 165,176 (291)
Nitrification amplifies the decreasing trends of atmospheric oxygen and implies a larger land carbon uptake [PDF]
, 2007 [1] Atmospheric O-2 trend measurements are used to partition global oceanic and land biotic carbon sinks on a multiannual basis. The underlying principle is that a terrestrial uptake or release of CO2 is accompanied by an opposite flux of O-2.
Bopp, L +4 more
core +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Observations of total RONO2 over the boreal forest: NO x sinks and HNO3 sources [PDF]
, 2013 In contrast with the textbook view of remote chemistry where HNO 3 formation is the primary sink of nitrogen oxides, recent theoretical analyses show that formation of RONO2 (ΣANs) from isoprene and other terpene precursors is the primary net chemical ...
Apel, E +13 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Aminoethyl nitrate – the novel super nitrate? [PDF]
British Journal of Pharmacology, 2009 Long‐term use of most organic nitrates is limited by development of tolerance, induction of oxidative stress and endothelial dysfunction. In this issue of the BJP, Schuhmacher et al. characterized a novel class of organic nitrates with amino moieties (aminoalkyl nitrates).
openaire +2 more sources
Simultaneous Determination of Nitrite and Nitrate in Milk Samples by Ion Chromatography Method and Estimation of Dietary Intake [PDF]
, 2016 The presence of nitrate and nitrite in foods may be considered hazardous after ingestion in the gastrointestinal tract due to their reaction with naturally occurred secondary amines to form potentially carcinogenic nitrosamines.
Chamandust, S. +6 more
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Biotechnologie, Agronomie, Société et Environnement, 2013 Impact of cattle stocking rate, under grazing, during autumn on potential nitrogen leaching: reference values established in the south-east of Belgium.
Hennart, S., Lambert, A., Stilmant, D.
doaj
Nitrates in the treatment of patients with coronary artery disease. The role of aerosol formulations
Медицинский совет, 2014 Nitrates have been commonly used in the treatment of patients with cardiovascular disease (CVD) for about 150 years. However, the feasibility and safety of nitrates in cardiology remains a matter of debate till today. Among CVDs, coronary artery disease (
AG Evdokimova, VV Evdokimov, NA Kozhina
doaj +1 more source
WETWALL - an innovative design concept for the treatment of wastewater at an urban scale [PDF]
, 2018 Rising temperatures, increasing food demand and scarcity of water and land resources highlight the importance of promoting the sustainable expansion of agriculture to our urban environment, while preserving water resources.
Arias, Carlos Alberto +7 more
core +4 more sources