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Effect of chronic benzodiazepine and benzodiazepine receptor agonist use on sleep architecture and brain oscillations in older adults with chronic insomnia. [PDF]

open access: yesSleep
Barbaux L   +20 more
europepmc   +1 more source

Seizure characteristics and neurological outcomes in pediatric anti-NMDAR encephalitis: a cohort study from Southern China. [PDF]

open access: yesNeurol Sci
Zhu H   +15 more
europepmc   +1 more source
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Nitrazepam (Mogadon) Dependence

British Journal of Psychiatry, 1975
Evidences suggest that the predisposed individual can develop dependence to various tranquillizers even to the extent of physical dependence similar to that seen with the barbiturates. Dependence can develop to benzodiazepine derivatives, and cases have been reported mainly for chlordiazepoxide, diazepam and oxazepam.
openaire   +2 more sources

Clinical Pharmacokinetics of Nitrazepam

Clinical Pharmacokinetics, 1981
Nitrazepam is one of the oldest benzodiazepines and is widely used as an hypnotic throughout the world, except North America, where it is not available. It is a safe hypnotic, with low acute toxicity and minor side effects. Development of tolerance or dependence and withdrawal symptoms are rare and very few known interactions with other drugs exist ...
L, Kangas, D D, Breimer
openaire   +2 more sources

Cimetidine impairs nitrazepam clearance

Clinical Pharmacology and Therapeutics, 1983
The effect of cimetidine on hepatic clearance of the benzodiazepine derivative nitrazepam was evaluated in healthy subjects. Six received a single 5- or 10-mg oral nitrazepam dose in the drug-free state and again with therapeutic cimetidine doses. Nitrazepam kinetics were determined from multiple serum concentrations measured during the 72 hr after ...
H R, Ochs   +5 more
openaire   +2 more sources

Nitrazepam in Myoclonic Epilepsies

Archives of Pediatrics & Adolescent Medicine, 1966
MYOCLONIC seizures of infancy and early childhood are generally resistant to conventional anticonvulsant drugs although their treatment has been facilitated in part by the use of corticotropin. 1,2 Corticotropin is advocated particularly in young infants with hypsarhythmia in the electroencephalogram; a beneficial response is unrelated to the apparent ...
J G, Millichap, W R, Ortiz
openaire   +2 more sources

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