Results 51 to 60 of about 2,926 (168)

The Number of Newly Dispensed Hypnotic Drugs During the First COVID‐19 Lockdown Period in The Netherlands

open access: yesJournal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT The 2019 coronavirus (COVID‐19) pandemic and associated lockdowns significantly disrupted healthcare systems, including access to pharmacological treatments such as sleep medication. This study investigated the number of first‐time dispensed hypnotic drugs during the first COVID‐19 lockdown in the Netherlands, using data from the Dutch ...
Dana M. Dijkgraaf   +5 more
wiley   +1 more source

Pharmacokinetics of Perampanel in Danish Paediatric Patients With Epilepsy Based on Therapeutic Drug Monitoring

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT We aimed to quantify inter‐ and intra‐patient variability in serum perampanel concentrations and assess whether concentrations predict efficacy or tolerability. We conducted a retrospective cohort study of 68 children and adolescents (< 18 years) treated at the Danish Epilepsy Centre (2017–2024), analysing 311 TDM samples.
Sara Angelucci   +5 more
wiley   +1 more source

A multi‐feature method for real‐time seizure detection in pediatric intensive care unit

open access: yesEpilepsia Open, Volume 11, Issue 1, Page 112-122, February 2026.
Abstract Purpose Continuous electroencephalogram (cEEG) monitoring is an important technique used in detecting electroclinical seizures in the pediatric intensive care unit (PICU). This study developed an artificial intelligence method for the real‐time automatic detection of seizures in the PICU.
Tian Sang   +10 more
wiley   +1 more source

A case report of microcephaly and refractory West syndrome associated with WDR62 mutation

open access: yesActa Epileptologica, 2020
The autosomal recessive form of primary microcephaly (MCPH) is a rare disorder characterized by microcephaly with variable degree of intellectual disability. WDR62 has been reported as the second causative gene of MCPH2.
Ping Zhou   +5 more
doaj   +1 more source

Real‐World Use of Cenobamate in Paediatric Drug‐Resistant Epilepsy: Long‐Term Efficacy, Safety, and Co‐Medication Adjustment

open access: yesEuropean Journal of Neurology, Volume 33, Issue 2, February 2026.
Cenobamate demonstrated high efficacy and long‐term retention in 78 children with drug‐resistant epilepsy. A ≥ 50% reduction in seizure frequency was achieved in 67.9% of patients, including 6.4% who became seizure‐free. Treatment was well tolerated and associated with a reduced overall drug load, supporting further prospective validation and ...
Tiziana Pisano   +10 more
wiley   +1 more source

Crises tônicas axiais e crises acinéticas: estudo clínico longitudinal de pacientes tratados com derivados benzodiazepinicos

open access: yesArquivos de Neuro-Psiquiatria, 1970
Com o uso de Nitrazepam notou-se rápida redução de freqüência das crises tônicas axiais. Os melhores resultados foram obtidos em um paciente que apresentava crises tônicas axiais isoladas, estado seqüela de encefalopatia mioclônica infantil com ...
Michel Pierre Lison
doaj   +1 more source

Syndromic and etiological classification predicts seizure freedom in childhood and youth onset epilepsy: A population‐based study from the Norwegian Mother, Father, and Child Cohort Study

open access: yesEpilepsia, Volume 67, Issue 2, Page 726-740, February 2026.
Abstract Objective This study was undertaken to determine the proportion of individuals with childhood and youth onset epilepsy who attain seizure freedom across seizure types, epilepsy types, etiologies, and syndromes using the latest International League Against Epilepsy (ILAE) classifications.
Truls Vikin   +5 more
wiley   +1 more source

Espasmos em flexão: estudo clínico longitudinal de pacientes tratados com Nitrazepam (mogadon) Massive spams: clinical study in patients treated by Nitrazepam

open access: yesArquivos de Neuro-Psiquiatria, 1970
O tratamento foi satisfatório em 11 dos 12 pacientes com espasmos em flexão. Em dois pacientes as crises foram controladas desde o primeiro dia. Em 9 houve redução rápida e significativa da intensidade e da freqüência dos surtos de espasmos em flexão ...
Michel Pierre Lison
doaj  

Technological Stress Prevention to Nutria (Myocastor coypus)

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Animal grouping, groups restructure, changing the docks and various technological operations causes disorders to the nutria manifested by aggressive behaviour. Tranquilizers prevent the stress and lower the catecholamine’s levels.
Cornel Igna   +5 more
doaj  

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