Results 51 to 60 of about 5,028 (210)

Clinical Study on Combining Traditional Chinese Medicine With Acupuncture for Treating Insomnia Accompanied by Anxiety

Brain and Behavior, Volume 16, Issue 6, June 2026.
In treating Qi stagnation type insomnia, the combination of traditional Chinese medicine and acupuncture can improve sleep quality, alleviate anxiety and depression, and improve physical fitness. Compared to using traditional Chinese medicine decoction alone for treatment, the combination of traditional Chinese medicine decoction and acupuncture has ...
Xue‐Wen Mao, Peng Bai
wiley   +1 more source

Efeito de medicamentos sobre tipos eletroclínicos de crises epilépticas na síndrome de Lennox-Gastaut

Arquivos de Neuro-Psiquiatria, 1977
Analisamos os resultados terapêuticos obtidos com o uso de diferentes drogas (diazepam, nitrazepam, clonazepam, difenilhidantoina, barbitúricos - fenobarbital e primidona -, dipropilacetato de sódio e ACTH) em 29 pacientes com síndrome de Lennox-Gastaut.
José Geraldo Speciali, Michel Pierre Lison   +1 more
doaj   +1 more source

Differential Functional Changes of Nav1.2 Channel Causing SCN2A-Related Epilepsy and Status Epilepticus During Slow Sleep

Frontiers in Neurology, 2021
Background: Nav1.2 encoded by the SCN2A gene is a brain-expressed voltage-gated sodium channel known to be associated with neurodevelopment disorders ranging from benign familial neonatal infantile seizures (BFIS) to developmental and epileptic ...
Pu Miao, Siyang Tang, Jia Ye, Jihong Tang, Jianda Wang, Chaoguang Zheng, Yuezhou Li, Jianhua Feng   +7 more
doaj   +1 more source

Use of Interval Therapy with Benzodiazepines to Prevent Seizure Recurrence in Stressful Situations

Brain Sciences, 2022
Introduction: Antiseizure medications (ASMs) control 70–75% of seizures. Accepting stress as a trigger for seizures, intervention, at the time of predictable stress, should offer a therapeutic option.
Roy G. Beran
doaj   +1 more source

Single‐nucleus RNA sequencing reveals ferroptosis as a potential contributor to the pathogenesis of focal cortical dysplasia

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
1. A single‐cell analysis was conducted to investigate the transcriptomic changes in cells within focal cortical dysplasia (FCD). 2. Ferroptosis may play a significant role in the pathogenesis of FCD, potentially contributing to cellular damage and epileptogenesis. 3.
Qingyang Zeng, Fengjun Zhu, Dezhi Cao, Yang Sun, Lin Li, Zeshi Tan, Cong Li, Xiaofan Ren, Yidi Liu, Zhiqiang Lin, Dongfang Zou   +10 more
wiley   +1 more source

The role of pharmacotherapy, rehabilitation and nutrition in the treatment of children with West syndrome

Journal of Education, Health and Sport, 2018
West syndrome is classified as an epileptic encephalopathy. This syndrome is diagnosed in children aged 4-6 months. Its unsuccessful prognosis and complicated aetiology affects the delay of psychomotor development and cognitive functions of children ...
Paulina Smyk, Ewa Barczykowska, Aneta Zreda-Pikies, Agata Ulenberg, Andrzej Kurylak   +4 more
doaj   +3 more sources

Ausências mioclônicas: estudo comparativo da potência anticonvulsivante do nitrazepam (Mogadon) e do diazepam (Valium) Myoclonic absences: a comparative study of the anticonvulsant potency of nitrazepan and diazepam

Arquivos de Neuro-Psiquiatria, 1969
Foi comparada a potência anticonvulsivamente do nitrazepam, do diazepam e da trimetadiona em 5 pacientes com ausências mioclônicas. Os doentes receberam, além das medicações anticonculsivantes, um placebo.
Michel Pierre Lison
doaj  

Effect of Cyclodextrin Complexation on the Aqueous Solubility of Diazepam and Nitrazepam: Phase-Solubility Analysis, Thermodynamic Properties

, 2012
The solubility enhancement of diazepam and nitrazepam in water was analyzed depending on temperature and amount of α-cyclodextrin ( α-CD), β-cyclodextrin (β-CD) and 2-hydroxypropyl-β-cyclodextrin (2-HP-β-CD).
J. Hadžiabdić, A. Elezović, O. Rahić, Indira Mujezin   +3 more
semanticscholar   +1 more source

Mechanisms of SCN2A loss of function do not predict presence or phenotype of epilepsy

Epilepsia, Volume 67, Issue 5, Page 2628-2653, May 2026.
Abstract Objective SCN2A loss‐of‐function (LoF) variants are associated with epilepsy (onset age ≥ 3 months), intellectual disability (ID), and autism spectrum disorder (ASD). Despite numerous identified variants and the description of phenotypic subgroups, relationships between Nav1.2 channel dysfunction and clinical phenotypes remain unclear.
Marsha Tan, Beatrice Southby Goad, Meagan Allen, Jill Rodda, Kay L. Richards, Simone L. Ardern‐Holmes, Daniel Bamborschke, Daniel Fritzen, Inna Hughes, Kate Riney, Ana Roche Martinez, Angelo Russo, Adriane Sinclair, Stefano Sartori, Marina Trivisano, Angela De Dominicis, Nicola Specchio, Rikke S. Møller, Ingrid E. Scheffer, Walid Fazeli, Markus Wolff, Steven Petrou, Katherine B. Howell, Géza Berecki   +23 more
wiley   +1 more source

The Mechanism Underlying the Abnormal Expression of α‐Synuclein in the Cortical Lesions of Patients With FCD Type IIb and TSC

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
The mTOR/GLT‐1 pathway abnormality induces α‐synucleinopathy, contributing to seizures in FCD lesions, which were rescued by treatment with the mTOR inhibitor Rapa or the GLT‐1 enhancer Cef. Intracerebroventricular α‐syn administration attenuated PTZ‐induced seizures in FCD models.
Li Zhang, Jian‐Ping Song, Jun Huang, Ping Liang, Hui Yang, Chun‐Qing Zhang, Kai‐Feng Shen   +6 more
wiley   +1 more source