Results 61 to 70 of about 5,028 (210)
Journal of Sleep Research, Volume 35, Issue 2, April 2026.ABSTRACT The 2019 coronavirus (COVID‐19) pandemic and associated lockdowns significantly disrupted healthcare systems, including access to pharmacological treatments such as sleep medication. This study investigated the number of first‐time dispensed hypnotic drugs during the first COVID‐19 lockdown in the Netherlands, using data from the Dutch ...
Dana M. Dijkgraaf +5 more
wiley +1 more source
Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.ABSTRACT We aimed to quantify inter‐ and intra‐patient variability in serum perampanel concentrations and assess whether concentrations predict efficacy or tolerability. We conducted a retrospective cohort study of 68 children and adolescents (< 18 years) treated at the Danish Epilepsy Centre (2017–2024), analysing 311 TDM samples.
Sara Angelucci +5 more
wiley +1 more source
Results in ChemistryWe report a docking-guided design, synthesis, and in vitro evaluation of nitrazepam-pyridinium aldoxime conjugates as bifunctional antidotes for organophosphate (paraoxon) poisoning that aim to combine acetylcholinesterase (AChE) reactivation with ...
Hamid Zangeneh +5 more
doaj +1 more source
A case report of microcephaly and refractory West syndrome associated with WDR62 mutation
Acta Epileptologica, 2020 The autosomal recessive form of primary microcephaly (MCPH) is a rare disorder characterized by microcephaly with variable degree of intellectual disability. WDR62 has been reported as the second causative gene of MCPH2.
Ping Zhou +5 more
doaj +1 more source
A multi‐feature method for real‐time seizure detection in pediatric intensive care unit
Epilepsia Open, Volume 11, Issue 1, Page 112-122, February 2026.Abstract Purpose Continuous electroencephalogram (cEEG) monitoring is an important technique used in detecting electroclinical seizures in the pediatric intensive care unit (PICU). This study developed an artificial intelligence method for the real‐time automatic detection of seizures in the PICU.
Tian Sang +10 more
wiley +1 more source
Arquivos de Neuro-Psiquiatria, 1970 Com o uso de Nitrazepam notou-se rápida redução de freqüência das crises tônicas axiais. Os melhores resultados foram obtidos em um paciente que apresentava crises tônicas axiais isoladas, estado seqüela de encefalopatia mioclônica infantil com ...
Michel Pierre Lison
doaj +1 more source
Arquivos de Neuro-Psiquiatria, 1970 O tratamento foi satisfatório em 11 dos 12 pacientes com espasmos em flexão. Em dois pacientes as crises foram controladas desde o primeiro dia. Em 9 houve redução rápida e significativa da intensidade e da freqüência dos surtos de espasmos em flexão ...
Michel Pierre Lison
doaj
Technological Stress Prevention to Nutria (Myocastor coypus)
Scientific Papers Animal Science and Biotechnologies, 2023 Animal grouping, groups restructure, changing the docks and various technological operations causes disorders to the nutria manifested by aggressive behaviour. Tranquilizers prevent the stress and lower the catecholamine’s levels.
Cornel Igna +5 more
doaj
EFICACIA DEL EXTRACTO FLUIDO DE PASSIFLORA INCARNATA L. EN LOS TRASTORNOS DE LA ANSIEDAD
Medicentro, 2011 Los pacientes aquejados de trastornos de ansiedad recurren frecuentemente a fármacos ansiolíticos, y son las benzodiazepinas las más usadas, entre ellas, el clorodiazepóxido, el diazepam y el nitrazepam, por su mayor disponibilidad.
Francisco Hernández Acosta +2 more
doaj