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Inducible nitric oxide synthase: Regulation, structure, and inhibition
A considerable number of human diseases have an inflammatory component, and a key mediator of immune activation and inflammation is inducible nitric oxide synthase (iNOS), which produces nitric oxide (NO) from l‐arginine.
Maris A Cinelli+2 more
exaly +2 more sources
Nitric oxide (NO) is a gas that is involved in many biologic processes. It is synthesized, by the NO synthases. The synthesis of NO by vascular endothelium is responsible for the vasodilator tone. In the central nervous system, it is a neurotransmitter, involved in the formation of memory; in the periphery, some nerves operate through NO-dependent ...
Xiomara, Garcia, Fernando, Stein
europepmc +3 more sources
Nitrated Fatty-Acids Distribution in Storage Biomolecules during Arabidopsis thaliana Development
The non-enzymatic interaction of polyunsaturated fatty acids with nitric oxide (NO) and derived species results in the formation of nitrated fatty acids (NO2-FAs).
Lorena Aranda-Caño+5 more
doaj +1 more source
In higher plants, hydrogen sulfide (H2S) is a recognized signaling molecule that performs multiple regulatory functions. The enzyme L-cysteine desulfhydrase (LCD) catalyzes the conversion of L-cysteine (L-Cys) to pyruvate and ammonium with the ...
Jorge De La O-Sánchez+3 more
doaj +1 more source
Endogenous Biosynthesis of S-Nitrosoglutathione From Nitro-Fatty Acids in Plants
Nitro-fatty acids (NO2-FAs) are novel molecules resulting from the interaction of unsaturated fatty acids and nitric oxide (NO) or NO-related molecules. In plants, it has recently been described that NO2-FAs trigger an antioxidant and a defence response ...
Capilla Mata-Pérez+9 more
doaj +1 more source
NADPH is an indispensable cofactor in a wide range of physiological processes that is generated by a family of NADPH dehydrogenases, of which the NADP-dependent malic enzyme (NADP-ME) is a member.
Jorge Taboada+4 more
doaj +1 more source
Nitric oxide (NO) is a free radical which modulates protein function and gene expression throughout all stages of plant development. Fruit ripening involves a complex scenario where drastic phenotypical and metabolic changes take place. Pepper fruits are
Salvador González-Gordo+5 more
doaj +1 more source
The Modus Operandi of Hydrogen Sulfide(H2S)-Dependent Protein Persulfidation in Higher Plants
Protein persulfidation is a post-translational modification (PTM) mediated by hydrogen sulfide (H2S), which affects the thiol group of cysteine residues from target proteins and can have a positive, negative or zero impact on protein function.
Francisco J. Corpas+4 more
doaj +1 more source
The class III peroxidases (PODs) catalyze the oxidation of several substrates coupled to the reduction of H2O2 to water, and play important roles in diverse plant processes.
Salvador González-Gordo+3 more
doaj +1 more source
Nitric oxide signalling in kidney regulation and cardiometabolic health
The prevalence of cardiovascular and metabolic disease coupled with kidney dysfunction is increasing worldwide. This triad of disorders is associated with considerable morbidity and mortality as well as a substantial economic burden.
M. Carlström
semanticscholar +1 more source