Results 41 to 50 of about 4,902,264 (349)

Nitric oxide-mediated modulation of the murine locomotor network [PDF]

, 2014
CD was supported by a BBSRC studentshipSpinal motor control networks are regulated by neuromodulatory systems to allow adaptability of movements. The present study aimed to elucidate the role of nitric oxide (NO) in the modulation of mammalian spinal ...
Miles, Gareth Brian, Foster, Joshua David, Sillar, Keith Thomas, Dunford, Catherine   +3 more
core   +1 more source

The utility of the nitric oxide electrochemical sensor in biomedical research [PDF]

, 2003
In recent years World Precision Instruments Inc. (WPI) produced for commercial use a selective and sensitive electrochemical sensor for the detection of the important biological free radical nitric oxide (NO).
John B. Clark, Clark, JB, Roger D. Hurst, Hurst, RD   +3 more
core   +1 more source

Nitric Oxide in Hypertension [PDF]

The Journal of Clinical Hypertension, 2006
Hypertension is a major risk factor for cardiovascular disease, and reduction of elevated blood pressure significantly reduces the risk of cardiovascular events. Endothelial dysfunction, which is characterized by impairment of nitric oxide (NO) bioavailability, is an important risk factor for both hypertension and cardiovascular disease and may ...
Hermann M, Flammer A, Lüscher TF
openaire   +3 more sources

The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway

Pharmacological Reviews, 2020
In contrast to nitric oxide, which has well established and important roles in the regulation of blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary system, and the inflammation response and host defense, its ...
V. Kapil, R. Khambata, Daniel A. Jones, K. Rathod, C. Primus, G. Massimo, J. Fukuto, A. Ahluwalia   +7 more
semanticscholar   +1 more source

Effects of nitric oxide synthase inhibitor - Nitro-L-Arginine Methyl Ester, on silica-inducated inflammatory reaction and apoptosis [PDF]

, 2006
BACKGROUND: Although nitric oxide is overproduced by macrophages and neutrophils after exposure to silica, its role in silica-induced inflammatory reaction and apoptosis needs further clarification.
He Wang, Wang, He, Leigh, James, Leigh James, James Leigh, Wang He   +5 more
core   +1 more source

Insulin-stimulated phosphorylation of endothelial nitric oxide synthase at serine-615 contributes to nitric oxide synthesis [PDF]

, 2009
Insulin stimulates endothelial NO (nitric oxide) synthesis via PKB (protein kinase B)/Akt-mediated phosphorylation and activation of eNOS (endothelial NO synthase) at Ser-1177.
Boyd, Alasdair R., Stuart A. Ritchie, Ian P. Salt, Salt, Ian P., Kohlhaas, Christine F, Yalla, Krishna C, Kohlhaas, Christine F., Boyd, Alasdair R, Krishna C. Yalla, Walsh, Kenneth, Ritchie, Stuart A, John M. C. Connell, Christine F. Kohlhaas, Kenneth Walsh, Ritchie, Stuart A., Connell, John M.C., Connell, John Mc, Salt, Ian P, Alasdair R. Boyd, Yalla, Krishna C.   +19 more
core   +1 more source

Differential sensitivity of basal and acetylcholine-induced activity of nitric oxide to blockade by asymmetric dimethylarginine (ADMA) in the rat aorta [PDF]

, 2010
<b>Background and purpose</b>: Previous work has shown that NG-monomethyl-l-arginine (l-NMMA) paradoxically inhibits basal, but not ACh-stimulated activity of nitric oxide in rat aorta.
Craig, J., AL-Zobaidy, M.J., John Craig, William Martin, Martin, W., Mohammed J AL-Zobaidy   +5 more
core   +1 more source

The gaseous messenger molecule, nitric oxide : a modulator of locomotor movements during early amphibian development [PDF]

, 2012
1. The free radical gas nitric oxide (NO) is now recognised as a ubiquitous and versatile signalling molecule and the investigation of its biological roles has involved a wide range of scientific disciplines in many different species. Yet despite this,
McLean, David L.
core   +2 more sources

Evaluation of the Binding Affinity of Nitrosylcobalamin to Intrinsic Factor as a Predictive Model for Cobalamin Binding Protein Interactions: A Comparative Study with Hydroxocobalamin

Frontiers in Bioscience-Elite
Background: Intrinsic factor (IF) is a glycoprotein crucial for cobalamin (vitamin B12) absorption in the human body. This study aimed to evaluate the binding affinity of nitrosylcobalamin (NO-Cbl), a cobalamin analog, to recombinant ...
Annette M. Sysel, Joseph A. Bauer
doaj   +1 more source

Biochemistry of Nitric Oxide [PDF]

Indian Journal of Clinical Biochemistry, 2011
Nitric oxide (NO) a free radical having both cytoprotective as well as tumor promoting agent is formed from l-arginine by converting it to l-citrulline via nitric oxide synthase enzymes. The reaction product of nitric oxide with superoxide generates potent oxidizing agent, peroxynitrite which is the main mediator of tissue and cellular injury ...
Safia, Habib, Asif, Ali
openaire   +2 more sources