Results 51 to 60 of about 4,902,264 (349)

The key role of nitric oxide in hypoxia: hypoxic vasodilation and energy supply-demand matching [PDF]

Significance: a mismatch between energy supply and demand induces tissue hypoxia with the potential to cause cell death and organ failure. Whenever arterial oxygen concentration is reduced, increases in blood flow - 'hypoxic vasodilation' - occur in an ...
Feelisch, Martin, Umbrello, Michele, Dyson, Alex, Singer, Mervyn   +3 more
core   +1 more source

Hypoxic transcription gene profiles under the modulation of nitric oxide in nuclear run on-microarray and proteomics [PDF]

, 2009
Background: Microarray analysis still remains a powerful tool to identify new components of the transcriptosome and it has helped to increase the knowledge of targets triggered by stress conditions such as hypoxia and nitric oxide.
Nathalie Dehne, Bernhard Brüne, Essler, Silke, Igwe, Emeka I., Silke Essler, Natalie Al-Furoukh, Igwe, Emeka I, Igwe Emeka I, Dehne, Nathalie, Essler Silke, Dehne Nathalie, Emeka I Igwe, Brüne, Bernhard, Al-Furoukh Natalie, Al-Furoukh, Natalie, Al-Furoukh, Natalie,, Brüne Bernhard   +16 more
core   +1 more source

Nitrosylcobalamin Selectively Targets Tumors via Cobalamin Uptake and Lysosomal Processing

Frontiers in Bioscience-Elite
Background: Nitrosylcobalamin (NO-Cbl) is a vitamin B12 analog designed to exploit the “Trojan horse” vulnerability created by the heightened need of cancer cells for cobalamin and one-carbon metabolism.
Joseph A. Bauer, Annette M. Sysel
doaj   +1 more source

Inducible Nitric Oxide Synthase: Regulation, Structure, and Inhibition

Medicinal research reviews (Print), 2019
A considerable number of human diseases have an inflammatory component, and a key mediator of immune activation and inflammation is inducible nitric oxide synthase (iNOS), which produces nitric oxide (NO) from l‐arginine.
Maris A. Cinelli, H. Do, Galen P. Miley, R. Silverman   +3 more
semanticscholar   +1 more source

Association of Vitamin D Receptor Gene Polymorphisms and Hypovitaminosis D with Reduced Bone Mineral Density in Survivors of Childhood Leukemia: A Study in Algerian Patients

Current Issues in Molecular Biology
Survivors of childhood leukemia are at increased risk of long-term skeletal complications, including reduced bone mineral density (BMD). Vitamin D deficiency and genetic variations in the vitamin D receptor (VDR) gene are important factors influencing ...
Wafa Khelaifia, Ines Gouaref, Fatma Zohra Djaballah-Ider, Nabila Bouterfas, Chafia Touil-Boukoffa, Assia Galleze   +5 more
doaj   +1 more source

Short-Term Low Temperature Induces Nitro-Oxidative Stress that Deregulates the NADP-Malic Enzyme Function by Tyrosine Nitration in Arabidopsis thaliana

Antioxidants, 2019
Low temperature (LT) negatively affects plant growth and development via the alteration of the metabolism of reactive oxygen and nitrogen species (ROS and RNS).
Juan C. Begara-Morales, Beatriz Sánchez-Calvo, María V. Gómez-Rodríguez, Mounira Chaki, Raquel Valderrama, Capilla Mata-Pérez, Javier López-Jaramillo, Francisco J. Corpas, Juan B. Barroso   +8 more
doaj   +1 more source

Oxidative Stress in Plants

Antioxidants, 2020
Environmental stresses negatively affect plant growth, development and crop productivity [...]
Mounira Chaki, Juan C. Begara-Morales, Juan B. Barroso   +2 more
doaj   +1 more source

Nitric oxide sensing in plants is mediated by proteolytic control of group VII ERF transcription factors [PDF]

, 2014
Nitric oxide (NO) is an important signaling compound in prokaryotes and eukaryotes. In plants, NO regulates critical developmental transitions and stress responses.
Coego, Alberto, Gray, Julie E., Pearce, S. P., Theodoulou, F. L., Marin-De La Rosa, N., Pearce, Simon P, Gibbs, Daniel J., Mendiondo, G. M., Lozano-Juste, J., Bachmair, A., Movahedi, Mahsa, Lozano-Juste, Jorge, Hamali, B., Movahedi, M., Sousa Correia, Cristina, Gray, Julie E, Theodoulou, Frederica L, Talloji, P., Gibbs, D. J., Le�n, Jos�, Marín-De La Rosa, Nora Alicia, Pearce, Simon P., Correia, Cristina Sousa, Talloji, Prabhavathi, Tome, D. F. A., Bachmair, Andreas, Alabadí, David, Tomé, Daniel F.A., Holdsworth, Michael J, Alabadi, D., Bassel, George W., Vicente Conde, J. V., Md Isa, Nurulhikma, Tomé, Daniel F A, Tomé, Daniel F. A., Marín-de la Rosa, Nora, Bassel, George, Alabad�, David, Hamali, Bulut, Mar�n-de la Rosa, Nora, Mendiondo, Guillermina M, Vicente Conde, Jorge, Berckhan, S., Beynon, Jim, Berckhan, Sophie, León, José, Tom�, Daniel F.A., Coego, A., Holdsworth, M. J., Isa, N. M., Isa, Nurulhikma M. D., Sousa Correia, C., Mendiondo, Guillermina M., Conde, Jorge Vicente, Coego González, Alberto, Leon, J., Bassel, G. W., Holdsworth, Michael J., Theodoulou, Frederica L., Gibbs, Daniel J; id_orcid, Bassel, George W, Beynon, J., ALABADÍ DIEGO, DAVID, Gray, J. E.   +63 more
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Nitric Oxide Therapy for Diabetic Wound Healing

Advanced Healthcare Materials, 2019
Nitric oxide (NO) represents a potential wound therapeutic agent due to its ability to regulate inflammation and eradicate bacterial infections. Two broad strategies exist to utilize NO for wound healing; liberating NO from endogenous reservoirs, and ...
Maggie J. Malone-Povolny, Sara E. Maloney, M. Schoenfisch   +2 more
semanticscholar   +1 more source

Nitric oxide and nitric oxide synthase in Huntington's disease [PDF]

Journal of Neuroscience Research, 2001
AbstractNitric oxide (NO) is a biologically active inorganic molecule produced when the semiessential amino acid l‐arginine is converted to l‐citrulline and NO via the enzyme nitric oxide synthase (NOS). NO is known to be involved in the regulation of many physiological processes, such as control of blood flow, platelet adhesion, endocrine function ...
openaire   +2 more sources